Xylometazoline
Medication
topical nasal decongestant
cold & flu
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
SG label: stuffy nose and blocked mucus in colds
When to take
SG label: up to 3 applications a day in each nostril
Take with
NHS: not alongside another blocked-nose medicine
Pros & cons
Pros
- SG label: starts to decongest within 2 minutes
- SG label: the effect lasts several hours
- HSA: general sale list — off the shelf in SG
Cons
- SG label: not for more than 7 consecutive days
- SG label: the 0.1% spray is for 12 years and over
- Prolonged use may make stuffiness return or worsen
Sources
- HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (never re-fetched), 3 xylometazoline rows, 27 Aug 2026 · read 2026-08-27
what it says
“OTRIVIN NASAL SPRAY 0.1% (SIN11624P), OTRIVIN NASAL DROPS 0.05% (SIN11622P) and SNUP STADA SPRAY 0.1% (SIN15198P) all read "General Sale List", ATC R01AA07”
- MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], Product information block · read 2026-08-27
what it says
“XYLOMETAZOLINE HCL - 1 MG/ML … Forensic Classification: GENERAL SALE LIST · Anatomical Therapeutic Chemical (ATC) code R01AA07 · Prescription-only Medicines with Exemptions for Supply without Prescription: NA”
- MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], What is Otrivin 0.1% and when is it used · read 2026-08-27
what it says
“It quickly decongests your stuffy nose and helps clear blocked mucus secretions … starts to decongest within 2 minutes and lasts for several hours … indicated in adults and in adolescents over 12 years of age.”
- MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], How should Otrivin 0.1% be used · read 2026-08-27
what it says
“Do not exceed 3 applications daily into each nostril … should not be used for more than 7 consecutive days. If symptoms persist, consult your doctor. Prolonged or excessive use may cause stuffiness in the nose to return or worsen.”
- MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], When must Otrivin 0.1% not be used · read 2026-08-27
what it says
“you have undergone recent trans-nasal surgery … you have narrow angle glaucoma … chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis); the child is below 12 years of age”
- NHS — Decongestants (conditions A–Z), what they are · read 2026-08-27
what it says
“Decongestants are a type of medicine that can provide short-term relief for a blocked or stuffy nose (nasal congestion) … They work by reducing the swelling of the blood vessels in your nose, which helps to open the airways.”
- NHS — Decongestants: who can take decongestants · read 2026-08-27
what it says
“They should not be used … without getting advice from a pharmacist or GP first: people with diabetes; people with high blood pressure; people with an overactive thyroid gland (hyperthyroidism); men with an enlarged prostate”
- NHS — Decongestants: how to use decongestants · read 2026-08-27
what it says
“Most decongestants should only be used between 1 and 4 times a day … Decongestant nasal sprays and drops should not be used for more than 5 days at a time”
- NHS — Decongestants: taking decongestants with other medicines · read 2026-08-27
what it says
“taking decongestants alongside some antidepressants can cause a dangerous rise in blood pressure. Do not use more than one medicine to treat a blocked nose at the same time. This includes using nasal sprays together or combining them with tablets”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.