{"ok":true,"entry":{"slug":"xylometazoline","kind":"medication","name":"xylometazoline","aliases":["Otrivin"],"brands_sg":["Otrivin","Snup Stada"],"class":"topical nasal decongestant","tags":["cold-flu"],"use_for":"sg label: stuffy nose and blocked mucus in colds","use_after":"sg label: up to 3 applications a day in each nostril","use_duration":null,"take_with":"nhs: not alongside another blocked-nose medicine","pros":["sg label: starts to decongest within 2 minutes","sg label: the effect lasts several hours","hsa: general sale list — off the shelf in sg"],"cons":["sg label: not for more than 7 consecutive days","sg label: the 0.1% spray is for 12 years and over","prolonged use may make stuffiness return or worsen"],"dose_note":"the singapore label maximum, from the moh national drug formulary page for OTRIVIN NASAL SPRAY 0.1% [SIN11624P], reads \"Do not exceed 3 applications daily into each nostril\", for a product \"indicated in adults and in adolescents over 12 years of age\", together with \"Like other nasal decongestants, Otrivin 0.1% should not be used for more than 7 consecutive days\" and \"Prolonged or excessive use may cause stuffiness in the nose to return or worsen.\" the sg register also lists OTRIVIN NASAL DROPS 0.05%, the lower strength. the nhs puts the general limit for decongestant sprays and drops at \"more than 5 days at a time\", and says most decongestants should only be used between 1 and 4 times a day. the pharmacist or doctor sets the dose.","dosage":null,"ul_status":null,"sg_class":"general-sale","cautions":["narrow-angle glaucoma — an sg label contraindication","rhinitis sicca or atrophic rhinitis — an sg label contraindication","recent trans-nasal surgery — an sg label contraindication","diabetes, high blood pressure, an overactive thyroid or an enlarged prostate — nhs advises asking first"],"clashes":[{"src":["nhs_dec_mix"],"note":"nhs: taken with decongestants they can cause a dangerous rise in blood pressure","with":"some antidepressants"},{"src":["nhs_dec_mix"],"note":"nhs: sprays should not be combined with each other or with tablets and capsules for congestion","with":"any second blocked-nose medicine"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (never re-fetched), 3 xylometazoline rows, 27 Aug 2026","quote":"OTRIVIN NASAL SPRAY 0.1% (SIN11624P), OTRIVIN NASAL DROPS 0.05% (SIN11622P) and SNUP STADA SPRAY 0.1% (SIN15198P) all read \"General Sale List\", ATC R01AA07","accessed":"2026-08-27"},{"id":"ndf_otrivin_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin11624p/","label":"MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], Product information block","quote":"XYLOMETAZOLINE HCL - 1 MG/ML … Forensic Classification: GENERAL SALE LIST · Anatomical Therapeutic Chemical (ATC) code R01AA07 · Prescription-only Medicines with Exemptions for Supply without Prescription: NA","accessed":"2026-08-27"},{"id":"ndf_otrivin_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin11624p/","label":"MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], What is Otrivin 0.1% and when is it used","quote":"It quickly decongests your stuffy nose and helps clear blocked mucus secretions … starts to decongest within 2 minutes and lasts for several hours … indicated in adults and in adolescents over 12 years of age.","accessed":"2026-08-27"},{"id":"ndf_otrivin_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin11624p/","label":"MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], How should Otrivin 0.1% be used","quote":"Do not exceed 3 applications daily into each nostril … should not be used for more than 7 consecutive days. If symptoms persist, consult your doctor. Prolonged or excessive use may cause stuffiness in the nose to return or worsen.","accessed":"2026-08-27"},{"id":"ndf_otrivin_contra","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin11624p/","label":"MOH National Drug Formulary — OTRIVIN NASAL SPRAY 0.1% [SIN11624P], When must Otrivin 0.1% not be used","quote":"you have undergone recent trans-nasal surgery … you have narrow angle glaucoma … chronic nasal inflammation with very dry nasal passages (rhinitis sicca or atrophic rhinitis); the child is below 12 years of age","accessed":"2026-08-27"},{"id":"nhs_dec_about","url":"https://www.nhs.uk/conditions/decongestants/","label":"NHS — Decongestants (conditions A–Z), what they are","quote":"Decongestants are a type of medicine that can provide short-term relief for a blocked or stuffy nose (nasal congestion) … They work by reducing the swelling of the blood vessels in your nose, which helps to open the airways.","accessed":"2026-08-27"},{"id":"nhs_dec_who","url":"https://www.nhs.uk/conditions/decongestants/","label":"NHS — Decongestants: who can take decongestants","quote":"They should not be used … without getting advice from a pharmacist or GP first: people with diabetes; people with high blood pressure; people with an overactive thyroid gland (hyperthyroidism); men with an enlarged prostate","accessed":"2026-08-27"},{"id":"nhs_dec_how","url":"https://www.nhs.uk/conditions/decongestants/","label":"NHS — Decongestants: how to use decongestants","quote":"Most decongestants should only be used between 1 and 4 times a day … Decongestant nasal sprays and drops should not be used for more than 5 days at a time","accessed":"2026-08-27"},{"id":"nhs_dec_mix","url":"https://www.nhs.uk/conditions/decongestants/","label":"NHS — Decongestants: taking decongestants with other medicines","quote":"taking decongestants alongside some antidepressants can cause a dangerous rise in blood pressure. Do not use more than one medicine to treat a blocked nose at the same time. This includes using nasal sprays together or combining them with tablets","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:34.039038+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}