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White mulberry leaf

Supplement botanical general nutrition
Aka: Morus alba, DNJ, 1-deoxynojirimycin
Brands seen in Singapore: Navitas Organics, Swanson Vitamins, Natural Factors, Life Extension, Foods Alive
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Post-meal glucose — the overall effect is still unsettled
Pros & cons
Pros
  • 12-trial meta-analysis: fasting glucose −0.47 mmol/l
  • SAMe analysis: hba1c and fasting insulin also fell
  • Second review: post-meal glucose and insulin lower
Cons
  • Second review: not enough to call it effective
  • Effect was larger in people with high fasting glucose
  • Leaf extract differs from the dried mulberry fruit
Sources
  1. Effect of mulberry leaf or mulberry leaf extract on glycemic traits: a systematic review and meta-analysis (Cui et al., Food Funct 2023) · read 2026-08-27
    what it says
    “Meta-analysis showed that ML/MLE supplementation resulted in a significant reduction in FBG by -0.47 mmol L-1, HbA1c by -2.92 mmol mol-1, and FPI by -0.58 μIU mL-1.”
  2. Cui et al. 2023 — trials and participants pooled · read 2026-08-27
    what it says
    “Twelve clinical trials (615 participants) fulfilled the eligibility criteria for the present meta-analysis, which included sensitivity analysis and GRADE certainty.”
  3. Cui et al. 2023 — who and how long the effect showed in · read 2026-08-27
    what it says
    “subgroup analysis indicated that long-term supplementation of ML/MLE (≥8 weeks) was more effective for regulation of the glycemic traits in the non-healthy and baseline FPG >6.1 mmol L-1 subgroups”
  4. Morus alba L. for Blood Sugar Management: A Systematic Review and Meta-Analysis (Jeong et al., Evid Based Complement Alternat Med 2022) · read 2026-08-27
    what it says
    “Our results showed that Morus alba can reduce postprandial glucose and insulin levels.”
  5. Jeong et al. 2022 — stated limits of that conclusion · read 2026-08-27
    what it says
    “However, it is insufficient to conclude that Morus alba is an effective intervention for lowering blood glucose levels. Therefore, more rigorous studies are needed to reveal the effect of MA on blood glucose levels.”
  6. HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025) — white mulberry / Morus alba / 1-deoxynojirimycin not listed in Annex A or B (PDF full text searched) · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  7. iHerb Singapore — “Mulberries” category page (no /c/mulberry-leaf page exists; that URL 404s), default (best-selling) order; no Singapore shipping-restriction notice shown · read 2026-08-27
    what it says
    “Navitas Organics, Organic Mulberry Berries, 8 oz (227 g) … Swanson Vitamins, Mulberry Leaf Extract, 500 mg … Swanson Vitamins, Full Spectrum Mulberry Leaf, 500 mg … Natural Factors, WellBetX, Mulberry Extract, 100 mg … Life Extension … Foods Alive”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.