{"ok":true,"entry":{"slug":"white-mulberry-leaf","kind":"supplement","name":"white mulberry leaf","aliases":["Morus alba","DNJ","1-deoxynojirimycin"],"brands_sg":["Navitas Organics","Swanson Vitamins","Natural Factors","Life Extension","Foods Alive"],"class":"botanical","tags":["general"],"use_for":"post-meal glucose — the overall effect is still unsettled","use_after":null,"use_duration":null,"take_with":null,"pros":["12-trial meta-analysis: fasting glucose −0.47 mmol/l","same analysis: hba1c and fasting insulin also fell","second review: post-meal glucose and insulin lower"],"cons":["second review: not enough to call it effective","effect was larger in people with high fasting glucose","leaf extract differs from the dried mulberry fruit"],"dose_note":"the 2023 meta-analysis pooled 12 randomised trials of mulberry leaf or leaf extract in 615 adults and reports no single dose, noting only that supplementation of 8 weeks or longer worked better in people whose fasting glucose was above 6.1 mmol/l — as directed on the label or by your pharmacist or doctor","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["on glucose-lowering treatment — reviews report glucose falling","leaf, not fruit — sg.iherb lists dried berries alongside leaf","healthy adults — the gain was mainly above 6.1 mmol/l fasting","hsa's prohibited list is not exhaustive; morus alba is absent"],"clashes":[],"sources":[{"id":"cui2023","url":"https://europepmc.org/article/MED/36644880","label":"Effect of mulberry leaf or mulberry leaf extract on glycemic traits: a systematic review and meta-analysis (Cui et al., Food Funct 2023)","quote":"Meta-analysis showed that ML/MLE supplementation resulted in a significant reduction in FBG by -0.47 mmol L-1, HbA1c by -2.92 mmol mol-1, and FPI by -0.58 μIU mL-1.","accessed":"2026-08-27"},{"id":"cui2023_scope","url":"https://europepmc.org/article/MED/36644880","label":"Cui et al. 2023 — trials and participants pooled","quote":"Twelve clinical trials (615 participants) fulfilled the eligibility criteria for the present meta-analysis, which included sensitivity analysis and GRADE certainty.","accessed":"2026-08-27"},{"id":"cui2023_subgroup","url":"https://europepmc.org/article/MED/36644880","label":"Cui et al. 2023 — who and how long the effect showed in","quote":"subgroup analysis indicated that long-term supplementation of ML/MLE (≥8 weeks) was more effective for regulation of the glycemic traits in the non-healthy and baseline FPG >6.1 mmol L-1 subgroups","accessed":"2026-08-27"},{"id":"jeong2022","url":"https://europepmc.org/article/MED/35656460","label":"Morus alba L. for Blood Sugar Management: A Systematic Review and Meta-Analysis (Jeong et al., Evid Based Complement Alternat Med 2022)","quote":"Our results showed that Morus alba can reduce postprandial glucose and insulin levels.","accessed":"2026-08-27"},{"id":"jeong2022_limits","url":"https://europepmc.org/article/MED/35656460","label":"Jeong et al. 2022 — stated limits of that conclusion","quote":"However, it is insufficient to conclude that Morus alba is an effective intervention for lowering blood glucose levels. Therefore, more rigorous studies are needed to reveal the effect of MA on blood glucose levels.","accessed":"2026-08-27"},{"id":"hsa_prohibited_2025","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025) — white mulberry / Morus alba / 1-deoxynojirimycin not listed in Annex A or B (PDF full text searched)","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/mulberry","label":"iHerb Singapore — “Mulberries” category page (no /c/mulberry-leaf page exists; that URL 404s), default (best-selling) order; no Singapore shipping-restriction notice shown","quote":"Navitas Organics, Organic Mulberry Berries, 8 oz (227 g) … Swanson Vitamins, Mulberry Leaf Extract, 500 mg … Swanson Vitamins, Full Spectrum Mulberry Leaf, 500 mg … Natural Factors, WellBetX, Mulberry Extract, 100 mg … Life Extension … Foods Alive","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:34.039038+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}