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Tranexamic acid

Medication antifibrinolytic other
Aka: Transamin, Cyklokapron
Brands seen in Singapore: Cyklokapron, Tranexamic Acid Mevon, Xamilux, Haemostop, Medsamic
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed to reduce heavy bleeding, e.g. heavy periods
When to take
HealthHub: for periods, not started before menses begin
Take with
Water · HealthHub: with or without food
Pros & cons
Pros
  • HealthHub: slows the breakdown of blood clots
  • NHS: 500 mg tablets; usual dose 2–3, 3 times a day
  • NHS: usually taken about 4 days for heavy periods
Cons
  • FDA: contraindicated with combined contraceptive pills
  • FDA: clots and retinal vein or artery occlusion seen
  • HealthHub: eyesight changes need urgent medical advice
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows; cached at /tmp/hsa_all.json and filtered locally, not re-fetched) · read 2026-08-27
    what it says
    “All 7 registered tranexamic acid products read Forensicclassification 'Prescription Only' — SIN02487P CYKLOKAPRON TABLET 500 mg · SIN17452P TRANEXAMIC ACID MEVON 500 MG · plus CYKLOKAPRON, XAMILUX, HAEMOSTOP, MEDSAMIC and TAFIXYL injections 100 mg/ml (B02AA02)”
  2. HealthHub (Pharmaceutical Society of Singapore) — Tranexamic acid: what is this medication for · read 2026-08-27
    what it says
    “Tranexamic acid is used to prevent or reduce excessive bleeding … known as an anti-fibrinolytic, which prevents blood clots from breaking down and hence, reduces the amount of blood lost.”
  3. HealthHub — Tranexamic acid: how should I take or use this medication · read 2026-08-27
    what it says
    “You may take this medication with or without food. If you are taking tranexamic acid for heavy menstrual bleeding, do not start taking the medicine until your menses have started.”
  4. HealthHub — Tranexamic acid: what precautions should I take · read 2026-08-27
    what it says
    “You have a history of or current medical conditions such as blood clots in your legs, lungs or anywhere else in your body, stroke, seizures (fits), or kidney problems.”
  5. HealthHub — Tranexamic acid: rare but serious side effects · read 2026-08-27
    what it says
    “Changes in eyesight e.g. blurred vision, changes in colour vision. Blood clot in the blood vessel (thrombosis) … you should stop your medication and see your healthcare professional immediately.”
  6. NHS — Tranexamic acid: how and when to take it (brand names: Cyklokapron, Evana Heavy Period Relief) · read 2026-08-27
    what it says
    “Tranexamic acid comes as 500mg tablets. For adults the usual dose is 2 or 3 tablets, taken 3 times a day … You'll usually take this medicine for 4 days for heavy periods”
  7. US FDA label for tranexamic acid tablets (Nordic Pharma), Indications and Usage, via openFDA (effective 2025-09-29) · read 2026-08-27
    what it says
    “Tranexamic acid USP tablets are indicated for the treatment of cyclic heavy menstrual bleeding in females of reproductive potential … an antifibrinolytic”
  8. US FDA label for tranexamic acid tablets (Nordic Pharma), section 2 Dosage and Administration, via openFDA · read 2026-08-27
    what it says
    “1,300 mg three times a day (3,900 mg/day) for a maximum of 5 days during monthly menstruation … Renal impairment: Lower dosage is needed … if serum creatinine concentration (Cr) is higher than 1.4 mg/dL”
  9. US FDA label for tranexamic acid tablets (Nordic Pharma), section 4 Contraindications, via openFDA · read 2026-08-27
    what it says
    “Concomitant use of combined hormonal contraceptives … Active thromboembolic disease or a history or intrinsic risk of thrombosis or thromboembolism, including retinal vein or artery occlusion … Hypersensitivity to tranexamic acid”
  10. US FDA label for tranexamic acid tablets (Nordic Pharma), section 5 Warnings and Precautions, via openFDA · read 2026-08-27
    what it says
    “Thromboembolism, including retinal occlusion, has been reported … Visual or ocular adverse reactions may occur … Cerebral edema and cerebral infarction may be caused by use … in patients with subarachnoid hemorrhage.”
  11. US FDA label for tranexamic acid tablets (Nordic Pharma), section 7 Drug Interactions, via openFDA · read 2026-08-27
    what it says
    “Concomitant therapy with tissue plasminogen activators may decrease the efficacy of both … not recommended in patients taking either Factor IX complex concentrates or anti-inhibitor coagulant concentrates … all-trans retinoic acid”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.