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Ticagrelor

Medication P2Y12 antiplatelet heart & blood pressure
Aka: Brilinta
Brands seen in Singapore: Ticaspan, Brilinta, Reclovac
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Preventing clots after acute coronary syndrome — SG label
When to take
Ndf: at least 12 months is the recommended duration
Take with
With or without food · grapefruit is to be avoided
Pros & cons
Pros
  • HealthHub: makes the blood less sticky to stop clots
  • Ndf: no dose change for age or kidney function
  • Brilinta, ticaspan and reclovac are the SG brands
Cons
  • Bleeding — nosebleeds, gums, cuts, heavier periods
  • HealthHub: feeling breathless easily is common
  • May need stopping before surgery or dental work
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; read from the cached copy at /tmp/hsa_all.json and filtered locally, not re-fetched · read 2026-08-27
    what it says
    “TICASPAN 90 FILM-COATED TABLETS 90MG SIN17211P; BRILINTA TABLET 60 MG SIN15294P; RECLOVAC 90 FILM COATED TABLETS 90MG SIN17266P; Brilinta Tablet 90 mg SIN14120P — all 4 ticagrelor rows read Prescription Only, ATC B01AC24”
  2. MOH National Drug Formulary (Singapore) — BRILINTA TABLET 90 MG [SIN14120P], product information · read 2026-08-27
    what it says
    “TICAGRELOR - 90 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code B01AC24 … Prescription-only Medicines with Exemptions for Supply without Prescription NA”
  3. MOH National Drug Formulary (Singapore) — BRILINTA [SIN14120P], section 4.1 Therapeutic indications · read 2026-08-27
    what it says
    “BRILINTA, co-administered with acetylsalicylic acid (ASA), is indicated for the prevention of thrombotic events (cardiovascular death, myocardial infarction and stroke) in patients with Acute Coronary Syndromes (ACS)”
  4. MOH National Drug Formulary (Singapore) — BRILINTA [SIN14120P], section 4.2 Posology and method of administration · read 2026-08-27
    what it says
    “BRILINTA treatment should be initiated with a single 180 mg loading dose (two tablets of 90 mg) and then continued at 90 mg twice daily. Treatment is recommended for at least 12 months”
  5. MOH National Drug Formulary (Singapore) — BRILINTA [SIN14120P], section 4.3 Contraindications · read 2026-08-27
    what it says
    “Active pathological bleeding. History of intracranial haemorrhage … Severe hepatic impairment … Co-administration of ticagrelor with strong CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, nefazodone, ritonavir, and atazanavir) is contraindicated”
  6. HealthHub (MOH Singapore) — Ticagrelor, medication information leaflet, uses (article last reviewed 22 May 2026) · read 2026-08-27
    what it says
    “Ticagrelor belongs to the class of medications called antiplatelets. Antiplatelets are used to prevent blood clots from forming by making the blood less “sticky”. By preventing blood clots, this reduces the risk of you having a heart attack or stroke.”
  7. HealthHub (MOH Singapore) — Ticagrelor, administration · read 2026-08-27
    what it says
    “Do not stop taking your medication without checking with your healthcare professional. You may take this medication with or without food.”
  8. HealthHub (MOH Singapore) — Ticagrelor, precautions · read 2026-08-27
    what it says
    “You have kidney or liver problems. You have a history of stomach or intestinal ulcers or bleeds, bleeding in the brain or other bleeding problems. You are planned for any medical procedures, surgeries or dental procedures”
  9. HealthHub (MOH Singapore) — Ticagrelor, common side effects · read 2026-08-27
    what it says
    “Feeling breathless easily … Mild bleeding such as: Unexplained nosebleed. Bleeding from gums when brushing teeth … Bleeding from small cuts for 10-15 minutes … Menstrual bleeding that is heavier than normal.”
  10. HealthHub (MOH Singapore) — Ticagrelor, food and medication to avoid · read 2026-08-27
    what it says
    “Avoid taking grapefruit when you are taking this medication … Examples include: Medications for bacterial infections (e.g. clarithromycin, erythromycin) … fungal infections (e.g. itraconazole, ketoconazole) … viral infections (e.g. atazanavir, darunavir, ritonavir)”
  11. MOH National Drug Formulary (Singapore) — BRILINTA [SIN14120P], section 4.2 Posology: continuation and companion aspirin dose · read 2026-08-27
    what it says
    “After one year, patients with MI initiated on 90 mg may continue treatment with 60 mg … Patients taking BRILINTA should also take a daily low maintenance dose of acetylsalicylic acid (ASA) of 75–150 mg”
  12. MOH National Drug Formulary (Singapore) — BRILINTA [SIN14120P], section 4.2 Posology: special populations · read 2026-08-27
    what it says
    “Elderly patients: No dose adjustment is required. Patients with renal impairment: No dose adjustment is necessary for patients with renal impairment”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.