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Sulforaphane

Supplement isothiocyanate general nutrition
Aka: broccoli sprout extract, glucoraphanin
Brands seen in Singapore: Swanson Vitamins, Jarrow Formulas, NOW Foods, Life Extension, Best Naturals
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Limited human evidence — trials are in clinical groups
Pros & cons
Pros
  • 6 ASD trials (n = 333) lowered a social-response score
  • Adverse-event rates matched placebo in the ASD trials
  • Not named in HSA's prohibited or restricted annexes
Cons
  • No cognitive benefit in the schizophrenia meta-analysis
  • PANSS total and positive symptoms did not improve
  • No RDA, no upper limit, no SG cap set
Sources
  1. Efficacy and safety of sulforaphane in schizophrenia: systematic review and meta-analysis of RCTs (BMC Psychiatry 2025) · read 2026-08-27
    what it says
    “Four RCTs with 369 schizophrenia patients were included. Sulforaphane did not significantly improve PANSS total or positive symptom scores … No cognitive benefits were observed.”
  2. Clinical efficacy, safety and molecular mechanism of sulforaphane in autism spectrum disorder: meta-analysis and network pharmacology (BMC Pharmacol Toxicol 2025) · read 2026-08-27
    what it says
    “Six trials involving 333 participants were included … 4-5 weeks and 8-10 weeks of sulforaphane supplementation significantly decreased the scores on the Social Responsiveness Scale … No significant difference … in the incidence of adverse events”
  3. HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annexes A and B · read 2026-08-27
    what it says
    “Annex A: List of substances which are prohibited or restricted for use with conditions … Annex B: List of substances with potential safety issues [sulforaphane appears in neither annex]”
  4. HSA — Health Supplements Guidelines (Jan 2026), Tables 4–5 vitamin and mineral limits · read 2026-08-27
    what it says
    “Table 4: Vitamins Limits … Table 5: Minerals Limits [neither table names sulforaphane]”
  5. iHerb Singapore — Broccoli category page (Supplements > Greens & Superfoods > Super Greens), default order · read 2026-08-27
    what it says
    “Swanson Vitamins, Sulforaphane from Broccoli Sprout Extract, 400 mcg … Jarrow Formulas, Vegan BroccoMax, 120 Veggie Capsules … NOW Foods, Real Food, Broccoli Seeds … Life Extension, Optimized Broccoli and Myrosinase … Best Naturals, Broccoli Sprout Extract”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.