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Solifenacin

Medication antimuscarinic other
Aka: Vesicare
Brands seen in Singapore: Vesicare, Synerrv, Solicin-5, Bladiton, Dalisoon
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Overactive bladder — urgency, frequency and leaks
When to take
SG label: 5 mg once daily, with or without food
Take with
Water — the SG label says tablets are swallowed whole
Pros & cons
Pros
  • SG label: one tablet a day, food makes no difference
  • SG label: the dose can be stepped up to 10 mg if needed
  • HSA: five generic brands registered besides vesicare
Cons
  • HealthHub: dry mouth, dry eyes and constipation
  • HealthHub: drowsiness and dizziness can affect driving
  • HealthHub: the body can overheat in hot weather
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; 5,511 rows cached at /tmp/hsa_all.json and filtered locally, never re-fetched — 8 solifenacin rows · read 2026-08-27
    what it says
    “All 8 registered solifenacin succinate products read "Prescription Only", ATC G04BD08, oral film-coated tablets 5 mg or 10 mg — Vesicare SIN13702P/SIN13703P, SYNERRV, SOLICIN-5, BLADITON, DALISOON and RENAXIN.”
  2. MOH National Drug Formulary — VESICARE TABLET 5MG [SIN13702P], Indications (SG package insert) · read 2026-08-27
    what it says
    “Vesicare is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency or increased urinary frequency.”
  3. MOH National Drug Formulary — VESICARE TABLET 5MG [SIN13702P], Dosage and Administration · read 2026-08-27
    what it says
    “The recommended dose is 5 mg solifenacin succinate once daily. If needed, the dose may be increased to a maximum of 10 mg solifenacin succinate once daily … swallowed whole with liquids … with or without food.”
  4. MOH National Drug Formulary — VESICARE TABLET 5MG [SIN13702P], Contraindications · read 2026-08-27
    what it says
    “patients with urinary retention … uncontrolled narrow-angle glaucoma … severe gastro-intestinal condition (including toxic megacolon and gastric retention) … myasthenia gravis … patients undergoing haemodialysis … severe hepatic impairment”
  5. MOH National Drug Formulary — VESICARE TABLET 5MG [SIN13702P], product information block · read 2026-08-27
    what it says
    “Forensic Classification: PRESCRIPTION ONLY MEDICINES · Anatomical Therapeutic Chemical (ATC) code G04BD08 · Prescription-only Medicines with Exemptions for Supply without Prescription: NA”
  6. HealthHub (National Medication Information workgroup / Pharmaceutical Society of Singapore) — Solifenacin: what is this medication for · read 2026-08-27
    what it says
    “Solifenacin is used to treat a condition called overactive bladder … a strong need to urinate with leaking or wetting incidence (urinary incontinence); a strong need to urinate right away (urgency); urinating often (frequency)”
  7. HealthHub — Solifenacin: how should I take or use this medication · read 2026-08-27
    what it says
    “This medication is usually taken once a day. You may take this medication with or without food.”
  8. HealthHub — Solifenacin: what precautions should I take · read 2026-08-27
    what it says
    “You are not able to empty your bladder (urinary retention) … delayed or slow emptying of your stomach … uncontrolled narrow angle glaucoma … liver, kidney or heart problems … dementia and is taking … Galantamine, Donepezil, Rivastigmine”
  9. HealthHub — Solifenacin: common side effects · read 2026-08-27
    what it says
    “Drowsiness — May affect your ability to drive and use machinery … Dizziness … Dry Mouth … Dry Eyes … Constipation … Overheating of the body — Monitor your body temperature, especially if you are in hot climates.”
  10. HealthHub — Solifenacin: what food or medication should I avoid · read 2026-08-27
    what it says
    “Avoid taking grapefruit, or grapefruit juice as they may interact with your medication and increase the risk of side-effects. Avoid drinking alcohol as it may increase the risk of dizziness, light-headedness or drowsiness.”
  11. NHS — Solifenacin: a medicine to treat symptoms of an overactive bladder (brand name Vesicare) · read 2026-08-27
    what it says
    “Solifenacin - Brand name: Vesicare. Find out how solifenacin treats symptoms of an overactive bladder, such as needing to pee more often, and how to take it.”
  12. NHS — Taking solifenacin with other medicines and herbal supplements · read 2026-08-27
    what it says
    “any medicine that makes you drowsy, gives you a dry mouth, or makes it difficult for you to pee – taking solifenacin might make these side effects worse; itraconazole … ritonavir”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.