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Sitagliptin

Medication DPP-4 inhibitor diabetes
Aka: Januvia
Brands seen in Singapore: Januvia, Pansiptin, Sitavitae, Jimandin, Instadip
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for type 2 diabetes, with diet and exercise
When to take
NHS: once a day, at the SAMe time each day
Take with
HealthHub: before or after food · NHS: swallowed whole
Pros & cons
Pros
  • NHS: one tablet a day, with or without food
  • HealthHub: raises insulin release after a meal
  • SG register lists 25, 50 and 100 mg tablets
Cons
  • NHS: with other diabetes medicines it can cause hypos
  • HealthHub: pancreatitis is a rare but serious risk
  • NHS: rare rash or blisters — stevens-johnson syndrome
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), sitagliptin rows, 27 Aug 2026 · read 2026-08-27
    what it says
    “JANUVIA 25/50/100 mg SIN13259P/SIN13258P/SIN13257P · PANSIPTIN SIN17192P · SITAVITAE SIN17161P · JIMANDIN SIN17267P · INSTADIP SIN17476P — ATC A10BH01; all 39 sitagliptin rows read Forensicclassification "Prescription Only"”
  2. NHS medicines A–Z — Sitagliptin: what sitagliptin is for (reviewed 19 August 2026) · read 2026-08-27
    what it says
    “Sitagliptin is a medicine used to treat type 2 diabetes. It's only available with a prescription … Sitagliptin works by increasing insulin in your body to lower your blood sugar level.”
  3. NHS medicines A–Z — Sitagliptin: how to take sitagliptin · read 2026-08-27
    what it says
    “Sitagliptin comes as tablets you take once a day … take it at the same time each day; swallow your tablets whole with a glass of water; you can take it with or without food”
  4. NHS medicines A–Z — Sitagliptin: side effects · read 2026-08-27
    what it says
    “A common side effect of sitagliptin is headaches … If you take sitagliptin alongside other diabetes medicines, it may cause low blood sugar (hypoglycaemia, or a hypo) … an itchy or painful rash, mouth ulcers or blisters … Stevens-Johnson syndrome”
  5. NHS medicines A–Z — Sitagliptin: taking sitagliptin with other medicines · read 2026-08-27
    what it says
    “You may not be able to take: medicines for high blood sugar, such as insulin, metformin and gliclazide; digoxin, a medicine for heart problems. If you take any of these medicines, your doctor may want to change your dose.”
  6. HealthHub (Pharmaceutical Society of Singapore / MOH) — Sitagliptin: what is this medication for · read 2026-08-27
    what it says
    “Sitagliptin is used in the treatment of diabetes by helping to increase the insulin release after a meal and decrease the amount of sugar made by the liver. It works together with lifestyle changes”
  7. HealthHub — Sitagliptin: how should I take or use this medication · read 2026-08-27
    what it says
    “This medication is taken once a day. You may take this medication before food or after food.”
  8. HealthHub — Sitagliptin: what precautions should I take · read 2026-08-27
    what it says
    “Have pancreas problems such as pancreatitis … Have gallstones, drink alcohol very often or have very high levels of triglycerides … Have kidney problems … do not take your medication until your blood has been taken”
  9. HealthHub — Sitagliptin: rare but serious side effects · read 2026-08-27
    what it says
    “Pancreatitis (inflammation of the pancreas) is a rare but serious side effect of this medication. Symptoms of pancreatitis include: Severe pain in the stomach, abdomen or back area”
  10. HealthHub — Sitagliptin: what food or medication should I avoid · read 2026-08-27
    what it says
    “Avoid taking alcohol with this medication as this increases your chances of developing pancreatitis.”
  11. JANUVIA (sitagliptin) tablets — US prescribing information (Merck, effective 2026-07-08) via openFDA drug/label.json, section 2 Dosage and Administration · read 2026-08-27
    what it says
    “The recommended dose of JANUVIA is 100 mg once daily. JANUVIA can be taken with or without food … eGFR 30 to less than 45: 50 mg once daily; eGFR less than 30: 25 mg once daily”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.