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Simethicone

Medication antiflatulent digestive
Aka: simeticone, dimethicone
Brands seen in Singapore: Simcone, Mylom, Gascoal, Hydrosil, Macgel
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Trapped wind, bloating and colic — evidence is weak
When to take
NHS: usually after meals and at bedtime
Take with
Water · chewable tablets chewed, bottles shaken first
Pros & cons
Pros
  • NHS: works in the gut only; safe in pregnancy
  • NHS: a very safe medicine, generally no side effects
  • SG register: 14 of 18 products are general sale list
Cons
  • NHS: we cannot be certain it really works
  • NHS: not much evidence it works for colic in babies
  • NHS: may stop levothyroxine being absorbed properly
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered locally, not re-fetched) · read 2026-08-27
    what it says
    “18 registered products contain simethicone/simeticone/dimethylpolysiloxane: 14 'General Sale List', 4 'Pharmacy Only'. All 4 single-ingredient rows are General Sale List — SIN11621P SIMCONE 80 mg · SIN02382P MYLOM DROPS · SIN07758P GASCOAL 50 mg · SIN09136P RIDWIND BABY DROP”
  2. Singapore National Drug Formulary — COLIMIX SYRUP [SIN03333P] (dicyclomine HCl 5 mg/5 ml + simethicone 50 mg/5 ml), Dosage · read 2026-08-27
    what it says
    “Adults: 10 ml 3 to 4 times daily and at bedtime … Children 4 to 12 years: 5 to 10 ml 4 times daily … Do not exceed the stated dose.”
  3. NHS — Simeticone: about simeticone · read 2026-08-27
    what it says
    “used to treat farting (flatulence), trapped wind and bloating, although we cannot be certain if it really works for these symptoms … It may also help with colic in babies, although there's not much scientific evidence”
  4. NHS — Simeticone: dosage and how to take it · read 2026-08-27
    what it says
    “For wind, the usual dose for adults is between 100mg and 250mg. You can take the medicine as needed, up to 3 or 4 times a day. You'll usually take it after meals and at bedtime.”
  5. NHS — Simeticone: dosage for babies, and doses varying by product · read 2026-08-27
    what it says
    “Doses of simeticone vary depending on the type of medicine, the brand and the amount of simeticone in it … For babies with colic, the usual dose is between 20mg and 40mg, up to 6 times a day.”
  6. NHS — Simeticone: how to take it · read 2026-08-27
    what it says
    “Shake the bottle. Measure the correct dose using a syringe, medicine spoon, or small measuring cup … Tablets, capsules and gel capsules Swallow these whole with some water. Chewable tablets Chew the tablets before swallowing.”
  7. NHS — Simeticone: how long to take it for · read 2026-08-27
    what it says
    “Simeticone is generally a safe medicine, so there's no strict limit on how long you or your baby can take it for … Talk to a doctor if you've been taking simeticone regularly for more than 14 days.”
  8. NHS — Simeticone: who can take simeticone · read 2026-08-27
    what it says
    “tell a pharmacist or doctor if you (or your child): have ever had an allergic reaction to simeticone or any ingredients it is combined with … are having treatment for a thyroid problem”
  9. NHS — Simeticone: side effects · read 2026-08-27
    what it says
    “Simeticone is a very safe medicine and is generally not known to cause any side effects … In rare cases it's possible to have a serious allergic reaction (anaphylaxis) to simeticone.”
  10. NHS — Simeticone and pregnancy, breastfeeding and fertility · read 2026-08-27
    what it says
    “Simeticone only works in your gut and does not get into your blood. It's safe to take if you are pregnant … Simeticone is OK to take while breastfeeding. It does not get into breast milk.”
  11. NHS — Simeticone: cautions with other medicines · read 2026-08-27
    what it says
    “talk to a doctor or pharmacist before you take simeticone if you are taking levothyroxine for thyroid problems. Simeticone might stop levothyroxine being absorbed properly, meaning it will not work as well.”
  12. NHS — Simeticone: mixing simeticone with herbal remedies and supplements · read 2026-08-27
    what it says
    “There's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with simeticone. They're not tested in the same way as pharmacy and prescription medicines.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.