{"ok":true,"entry":{"slug":"simethicone","kind":"medication","name":"simethicone","aliases":["simeticone","dimethicone"],"brands_sg":["Simcone","Mylom","Gascoal","Hydrosil","Macgel"],"class":"antiflatulent","tags":["digestive"],"use_for":"trapped wind, bloating and colic — evidence is weak","use_after":"nhs: usually after meals and at bedtime","use_duration":null,"take_with":"water · chewable tablets chewed, bottles shaken first","pros":["nhs: works in the gut only; safe in pregnancy","nhs: a very safe medicine, generally no side effects","sg register: 14 of 18 products are general sale list"],"cons":["nhs: we cannot be certain it really works","nhs: not much evidence it works for colic in babies","nhs: may stop levothyroxine being absorbed properly"],"dose_note":"no singapore package insert for a single-ingredient simethicone product is published on the national drug formulary, so the nearest stated ceiling read was nhs guidance for simeticone: “for wind, the usual dose for adults is between 100mg and 250mg. you can take the medicine as needed, up to 3 or 4 times a day” and, “for babies with colic, the usual dose is between 20mg and 40mg, up to 6 times a day”. nhs also notes doses “vary depending on the type of medicine, the brand and the amount of simeticone in it”, and suggests “talk to a doctor if you've been taking simeticone regularly for more than 14 days”. the sg colimix syrup insert (dicyclomine plus simethicone 50 mg/5 ml) adds “do not exceed the stated dose”. sg strengths range from 20 mg to 100 mg/ml. as directed on the label or by your pharmacist.","dosage":null,"ul_status":null,"sg_class":"general-sale","cautions":["having treatment for a thyroid problem — nhs: tell a pharmacist or doctor","allergy to any ingredient it is combined with — nhs: tell a pharmacist","regular use beyond 14 days — nhs: talk to a doctor","a baby whose colic does not improve — nhs: talk to a doctor or health visitor"],"clashes":[{"src":["nhs_simeti_inter"],"note":"nhs: simeticone might stop levothyroxine being absorbed properly, meaning it will not work as well","with":"levothyroxine"},{"src":["nhs_simeti_herbal"],"note":"nhs: there's not enough information to say they are safe to take with simeticone","with":"herbal remedies and supplements"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered locally, not re-fetched)","quote":"18 registered products contain simethicone/simeticone/dimethylpolysiloxane: 14 'General Sale List', 4 'Pharmacy Only'. All 4 single-ingredient rows are General Sale List — SIN11621P SIMCONE 80 mg · SIN02382P MYLOM DROPS · SIN07758P GASCOAL 50 mg · SIN09136P RIDWIND BABY DROP","accessed":"2026-08-27"},{"id":"ndf_colimix_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin03333p/","label":"Singapore National Drug Formulary — COLIMIX SYRUP [SIN03333P] (dicyclomine HCl 5 mg/5 ml + simethicone 50 mg/5 ml), Dosage","quote":"Adults: 10 ml 3 to 4 times daily and at bedtime … Children 4 to 12 years: 5 to 10 ml 4 times daily … Do not exceed the stated dose.","accessed":"2026-08-27"},{"id":"nhs_simeti_about","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: about simeticone","quote":"used to treat farting (flatulence), trapped wind and bloating, although we cannot be certain if it really works for these symptoms … It may also help with colic in babies, although there's not much scientific evidence","accessed":"2026-08-27"},{"id":"nhs_simeti_dose","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: dosage and how to take it","quote":"For wind, the usual dose for adults is between 100mg and 250mg. You can take the medicine as needed, up to 3 or 4 times a day. You'll usually take it after meals and at bedtime.","accessed":"2026-08-27"},{"id":"nhs_simeti_dose_baby","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: dosage for babies, and doses varying by product","quote":"Doses of simeticone vary depending on the type of medicine, the brand and the amount of simeticone in it … For babies with colic, the usual dose is between 20mg and 40mg, up to 6 times a day.","accessed":"2026-08-27"},{"id":"nhs_simeti_how","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: how to take it","quote":"Shake the bottle. Measure the correct dose using a syringe, medicine spoon, or small measuring cup … Tablets, capsules and gel capsules Swallow these whole with some water. Chewable tablets Chew the tablets before swallowing.","accessed":"2026-08-27"},{"id":"nhs_simeti_long","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: how long to take it for","quote":"Simeticone is generally a safe medicine, so there's no strict limit on how long you or your baby can take it for … Talk to a doctor if you've been taking simeticone regularly for more than 14 days.","accessed":"2026-08-27"},{"id":"nhs_simeti_who","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: who can take simeticone","quote":"tell a pharmacist or doctor if you (or your child): have ever had an allergic reaction to simeticone or any ingredients it is combined with … are having treatment for a thyroid problem","accessed":"2026-08-27"},{"id":"nhs_simeti_se","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: side effects","quote":"Simeticone is a very safe medicine and is generally not known to cause any side effects … In rare cases it's possible to have a serious allergic reaction (anaphylaxis) to simeticone.","accessed":"2026-08-27"},{"id":"nhs_simeti_preg","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone and pregnancy, breastfeeding and fertility","quote":"Simeticone only works in your gut and does not get into your blood. It's safe to take if you are pregnant … Simeticone is OK to take while breastfeeding. It does not get into breast milk.","accessed":"2026-08-27"},{"id":"nhs_simeti_inter","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: cautions with other medicines","quote":"talk to a doctor or pharmacist before you take simeticone if you are taking levothyroxine for thyroid problems. Simeticone might stop levothyroxine being absorbed properly, meaning it will not work as well.","accessed":"2026-08-27"},{"id":"nhs_simeti_herbal","url":"https://www.nhs.uk/medicines/simeticone/","label":"NHS — Simeticone: mixing simeticone with herbal remedies and supplements","quote":"There's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with simeticone. They're not tested in the same way as pharmacy and prescription medicines.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:31.341231+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}