Semaglutide
Medication
GLP-1 receptor agonist
diabetes
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for type 2 diabetes or obesity — a doctor decides
When to take
NHS: the injection is weekly; the tablets are daily
Take with
NHS tablets: water only, then 30 minutes before food
Pros & cons
Pros
- NHS: the injection is once a week, any time of day
- HSA: injection and tablet forms both registered in SG
- NHS: reduces appetite alongside diet and exercise
Cons
- NHS: nausea, vomiting, constipation, diarrhoea
- NHS: rare pancreatitis and worsening eye disease
- NHS: not used in pregnancy or while breastfeeding
Sources
- HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered offline) · read 2026-08-27
what it says
“All 15 registered semaglutide products carry Forensicclassification 'Prescription Only' (ATC A10BJ06) — 10 WEGOVY rows to 2.4 mg/dose, 3 RYBELSUS tablet rows (3, 7, 14 mg) and 2 OZEMPIC injection rows (0.25/0.5 mg and 1 mg per dose).”
- NHS Medicines A-Z — Semaglutide: what semaglutide is for · read 2026-08-27
what it says
“Semaglutide is a GLP-1 agonist medicine that can be used to treat type 2 diabetes, heart disease or obesity. It's only available with a prescription … works for weight loss by reducing your appetite”
- NHS Medicines A-Z — Semaglutide: how to use semaglutide · read 2026-08-27
what it says
“Semaglutide comes as an injection that you give yourself once a week or tablets that you take once a day … wait at least 30 minutes before eating, drinking or taking other medicines … swallow tablets whole”
- NHS Medicines A-Z — Semaglutide: side effects · read 2026-08-27
what it says
“Common side effects of semaglutide include: feeling sick (nausea) and being sick (vomiting); constipation; diarrhoea; feeling tired … Possible serious side effects … diabetic retinopathy getting worse … an inflamed pancreas (acute pancreatitis) … low blood sugar”
- NHS Medicines A-Z — Semaglutide: who can and cannot use it, pregnancy and breastfeeding · read 2026-08-27
what it says
“it may not be suitable if: … you have or have had an inflamed pancreas (acute pancreatitis) … not used while breastfeeding … not used during pregnancy … stop at least 2 months before you start trying”
- NHS Medicines A-Z — Semaglutide: using it with other medicines, food and drink · read 2026-08-27
what it says
“some medicines to reduce blood clots such as warfarin; levothyroxine, for an underactive thyroid; insulin – your doctor or specialist nurse may need to adjust your dose; other type 2 diabetes medicines … a general anaesthetic”
- US FDA label for OZEMPIC (semaglutide) injection, section 2.2 Recommended Dosage, via openFDA drug/label.json (effective 2026-07-30) · read 2026-08-27
what it says
“The recommended maintenance dosage is 0.5 mg, 1 mg, or 2 mg, injected subcutaneously once weekly, based on glycemic control.”
- US FDA label for WEGOVY (semaglutide) injection, section 2.2 Recommended Dosage in Adults, via openFDA drug/label.json (effective 2024-04-23) · read 2026-08-27
what it says
“The maintenance dosage of WEGOVY in adults is either 2.4 mg (recommended) or 1.7 mg once weekly. The maintenance dosage of WEGOVY in pediatric patients aged 12 years and older is 2.4 mg once weekly.”
- US FDA label for RYBELSUS (semaglutide) tablets, section 2.2 Recommended Dosage, via openFDA drug/label.json (effective 2026-01-30) · read 2026-08-27
what it says
“On Day 61 or thereafter, if: … Additional glycemic control is needed, increase the dosage to 14 mg orally once daily … Do not take more than one tablet per day.”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.