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Rosuvastatin

Medication statin heart & blood pressure
Aka: Crestor, rosuvastatin calcium
Brands seen in Singapore: Crestor, Rosuvor, Celmantin, Rovalux, Roswera
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for high cholesterol — a doctor decides
When to take
NHS: once a day, SAMe time each day, with or without food
Take with
Water · FDA: at least 2 h before al/mg antacids
Pros & cons
Pros
  • NHS: once a day, with or without food
  • HealthHub: may reduce heart attack and stroke risk
  • NHS: you can eat as normal while taking it
Cons
  • NHS: headache, dizziness, nausea, muscle aches
  • NHS: rare liver, pancreas or muscle damage
  • NHS: not recommended during pregnancy
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, filtered locally for rosuvastatin) · read 2026-08-27
    what it says
    “All 52 registered rosuvastatin products (44 single-ingredient, 8 with ezetimibe) carry Forensicclassification 'Prescription Only' — SIN12157P CRESTOR TABLET 20 mg; SIN16836P ROSUVOR; SIN16098P CELMANTIN; SIN16230P ROVALUX; SIN16659P ROSWERA”
  2. NHS Medicines A-Z — Rosuvastatin: what rosuvastatin is for · read 2026-08-27
    what it says
    “Rosuvastatin is a medicine used to treat high cholesterol and prevent heart attacks and strokes. You can only get it with a prescription.”
  3. NHS Medicines A-Z — Rosuvastatin: how to take it · read 2026-08-27
    what it says
    “swallow tablets or capsules whole with a drink of water ... take it once a day - try to take it at the same time each day ... you can take it with or without food”
  4. NHS Medicines A-Z — Rosuvastatin: common side effects · read 2026-08-27
    what it says
    “Common side effects of rosuvastatin include: a headache; dizziness; feeling sick (nausea); digestive problems, such as constipation, diarrhoea, indigestion or farting; muscle aches; sleep problems”
  5. NHS Medicines A-Z — Rosuvastatin: serious side effects · read 2026-08-27
    what it says
    “Possible serious side effects of rosuvastatin include: inflammation of the liver (hepatitis) ... inflammation of the pancreas (pancreatitis) ... inflammation and damage to the muscles”
  6. NHS Medicines A-Z — Rosuvastatin: who can and cannot take it · read 2026-08-27
    what it says
    “you have liver or kidney problems, or an underactive thyroid (hypothyroidism); you or a close family member have a condition that affects the muscles, such as myasthenia gravis; you regularly drink a lot of alcohol”
  7. NHS Medicines A-Z — Rosuvastatin: pregnancy · read 2026-08-27
    what it says
    “Rosuvastatin is not recommended during pregnancy because it can affect how your baby develops. If you're planning to get pregnant, stop taking rosuvastatin 3 months before you start trying to conceive.”
  8. NHS Medicines A-Z — Rosuvastatin: taking it with other medicines · read 2026-08-27
    what it says
    “other medicines for lowering cholesterol, such as fibrates ... antibiotics such as fusidic acid or erythromycin ... medicines to prevent blood clots such as warfarin or clopidogrel ... ciclosporin, a medicine given after an organ transplant”
  9. NHS Medicines A-Z — Rosuvastatin: food, drink and alcohol · read 2026-08-27
    what it says
    “You can eat as normal while taking rosuvastatin. It's best not to drink too much alcohol while taking rosuvastatin, as it can increase the risk of side effects like liver problems.”
  10. HealthHub (Pharmaceutical Society of Singapore) — Rosuvastatin: what is this medication for · read 2026-08-27
    what it says
    “High 'bad cholesterol' levels can cause your blood vessels to clog up and lead to chest pain (angina), heart attack or stroke. Hence, statins may reduce your risk for heart attack and stroke.”
  11. HealthHub — Rosuvastatin: what food or medication should I avoid · read 2026-08-27
    what it says
    “Avoid taking a supplement called red yeast rice as this supplement may increase the risk of side-effects ... Warfarin, a blood thinning medication; Medications for bacterial infections (e.g. clarithromycin, erythromycin)”
  12. US FDA label for CRESTOR (rosuvastatin calcium), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2026-04-29) · read 2026-08-27
    what it says
    “The dosage range for CRESTOR is 5 to 40 mg orally once daily ... Recommended Dosage in Asian Patients Initiate CRESTOR at 5 mg orally once daily due to increased rosuvastatin plasma concentrations”
  13. US FDA label for CRESTOR, section 2.1 General Dosage and Administration Information · read 2026-08-27
    what it says
    “When taking CRESTOR with an aluminum and magnesium hydroxide combination antacid, administer CRESTOR at least 2 hours before the antacid”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.