{"ok":true,"entry":{"slug":"rosuvastatin","kind":"medication","name":"rosuvastatin","aliases":["Crestor","rosuvastatin calcium"],"brands_sg":["Crestor","Rosuvor","Celmantin","Rovalux","Roswera"],"class":"statin","tags":["heart-bp"],"use_for":"prescribed for high cholesterol — a doctor decides","use_after":"nhs: once a day, same time each day, with or without food","use_duration":null,"take_with":"water · fda: at least 2 h before al/mg antacids","pros":["nhs: once a day, with or without food","healthhub: may reduce heart attack and stroke risk","nhs: you can eat as normal while taking it"],"cons":["nhs: headache, dizziness, nausea, muscle aches","nhs: rare liver, pancreas or muscle damage","nhs: not recommended during pregnancy"],"dose_note":"the us fda label for crestor states 'The dosage range for CRESTOR is 5 to 40 mg orally once daily' — 40 mg once daily is the adult label maximum; the same label says to initiate asian patients at 5 mg once daily and to 'consider risks and benefits' if not controlled at dosages up to 20 mg once daily. sg-registered tablets run 5, 10, 20 and 40 mg. in singapore the prescriber sets the dose, as directed on the label or by your pharmacist or doctor.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["liver or kidney problems, or an underactive thyroid (nhs)","pregnancy or planning one — nhs: not recommended, stop 3 months before trying","a muscle condition such as myasthenia gravis, in you or close family (nhs)","asian ancestry — fda label starts dosing at 5 mg once daily"],"clashes":[{"src":["hh_rosu_food"],"note":"healthhub: this supplement may increase the risk of side-effects","with":"red yeast rice"},{"src":["fda_crestor_antacid"],"note":"fda label: rosuvastatin is given at least 2 hours before the antacid","with":"aluminium/magnesium antacids"},{"src":["nhs_rosu_mix","hh_rosu_food"],"note":"nhs lists blood-clot medicines among those that may not mix well; healthhub names warfarin","with":"warfarin, clopidogrel"},{"src":["nhs_rosu_mix","hh_rosu_food"],"note":"nhs and healthhub both flag these antibiotics with statins","with":"erythromycin, clarithromycin, fusidic acid"},{"src":["nhs_rosu_mix"],"note":"nhs lists all of these among medicines that may not mix well with rosuvastatin","with":"fibrates, ciclosporin, hiv or hepatitis c medicines, the combined pill"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, filtered locally for rosuvastatin)","quote":"All 52 registered rosuvastatin products (44 single-ingredient, 8 with ezetimibe) carry Forensicclassification 'Prescription Only' — SIN12157P CRESTOR TABLET 20 mg; SIN16836P ROSUVOR; SIN16098P CELMANTIN; SIN16230P ROVALUX; SIN16659P ROSWERA","accessed":"2026-08-27"},{"id":"nhs_rosu_about","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: what rosuvastatin is for","quote":"Rosuvastatin is a medicine used to treat high cholesterol and prevent heart attacks and strokes. You can only get it with a prescription.","accessed":"2026-08-27"},{"id":"nhs_rosu_howto","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: how to take it","quote":"swallow tablets or capsules whole with a drink of water ... take it once a day - try to take it at the same time each day ... you can take it with or without food","accessed":"2026-08-27"},{"id":"nhs_rosu_side","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: common side effects","quote":"Common side effects of rosuvastatin include: a headache; dizziness; feeling sick (nausea); digestive problems, such as constipation, diarrhoea, indigestion or farting; muscle aches; sleep problems","accessed":"2026-08-27"},{"id":"nhs_rosu_serious","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: serious side effects","quote":"Possible serious side effects of rosuvastatin include: inflammation of the liver (hepatitis) ... inflammation of the pancreas (pancreatitis) ... inflammation and damage to the muscles","accessed":"2026-08-27"},{"id":"nhs_rosu_who","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: who can and cannot take it","quote":"you have liver or kidney problems, or an underactive thyroid (hypothyroidism); you or a close family member have a condition that affects the muscles, such as myasthenia gravis; you regularly drink a lot of alcohol","accessed":"2026-08-27"},{"id":"nhs_rosu_preg","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: pregnancy","quote":"Rosuvastatin is not recommended during pregnancy because it can affect how your baby develops. If you're planning to get pregnant, stop taking rosuvastatin 3 months before you start trying to conceive.","accessed":"2026-08-27"},{"id":"nhs_rosu_mix","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: taking it with other medicines","quote":"other medicines for lowering cholesterol, such as fibrates ... antibiotics such as fusidic acid or erythromycin ... medicines to prevent blood clots such as warfarin or clopidogrel ... ciclosporin, a medicine given after an organ transplant","accessed":"2026-08-27"},{"id":"nhs_rosu_food","url":"https://www.nhs.uk/medicines/rosuvastatin/","label":"NHS Medicines A-Z — Rosuvastatin: food, drink and alcohol","quote":"You can eat as normal while taking rosuvastatin. It's best not to drink too much alcohol while taking rosuvastatin, as it can increase the risk of side effects like liver problems.","accessed":"2026-08-27"},{"id":"hh_rosu_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/rosuvastatin","label":"HealthHub (Pharmaceutical Society of Singapore) — Rosuvastatin: what is this medication for","quote":"High 'bad cholesterol' levels can cause your blood vessels to clog up and lead to chest pain (angina), heart attack or stroke. Hence, statins may reduce your risk for heart attack and stroke.","accessed":"2026-08-27"},{"id":"hh_rosu_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/rosuvastatin","label":"HealthHub — Rosuvastatin: what food or medication should I avoid","quote":"Avoid taking a supplement called red yeast rice as this supplement may increase the risk of side-effects ... Warfarin, a blood thinning medication; Medications for bacterial infections (e.g. clarithromycin, erythromycin)","accessed":"2026-08-27"},{"id":"fda_crestor_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22CRESTOR%22&limit=1","label":"US FDA label for CRESTOR (rosuvastatin calcium), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2026-04-29)","quote":"The dosage range for CRESTOR is 5 to 40 mg orally once daily ... Recommended Dosage in Asian Patients Initiate CRESTOR at 5 mg orally once daily due to increased rosuvastatin plasma concentrations","accessed":"2026-08-27"},{"id":"fda_crestor_antacid","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22CRESTOR%22&limit=1","label":"US FDA label for CRESTOR, section 2.1 General Dosage and Administration Information","quote":"When taking CRESTOR with an aluminum and magnesium hydroxide combination antacid, administer CRESTOR at least 2 hours before the antacid","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}