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Resveratrol

Supplement polyphenol heart & metabolicgeneral nutrition
Aka: trans-resveratrol, Japanese knotweed extract
Brands seen in Singapore: California Gold Nutrition, Thorne, Life Extension, ProHealth Longevity, Doctor's Best
Third-party tested: Thorne certifies other products with NSF Certified for Sport, but nothing for resveratrol.Certification is granted per product, so check the tub you actually own. Not being listed is not the same as failing.
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Limited human evidence — 4 of 129 outcomes rated high
Pros & cons
Pros
  • 45 systematic reviews, rated moderate-to-high quality
  • 4 outcomes reached high-certainty grade evidence
  • 129 human associations have been graded, not guessed
Cons
  • 125 of 129 outcomes fell short of high certainty
  • The high-certainty findings sit in patient groups
  • No NIH ODS or NCCIH fact sheet exists to check it
Sources
  1. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of RCTs (Nutrition Journal, Apr 2026; PMC13196030) · read 2026-08-27
    what it says
    “Forty-five systematic reviews with 129 associations between resveratrol supplementation and human health were included, which consists of 68 outcomes. Using the AMSTAR measurement tool, all articles were categorized as moderate-to-high quality.”
  2. Nutrition Journal 2026 umbrella review — GRADE certainty of the significant associations · read 2026-08-27
    what it says
    “Among 35 significant associations, four were supported by high-certainty evidence according to GRADE, including positive effects of resveratrol supplementation on reducing waist circumference … total cholesterol among overweight adults … blood pressure … among patients with type 2 diabetes”
  3. Nutrition Journal 2026 umbrella review — what sits at moderate certainty · read 2026-08-27
    what it says
    “moderate-certainty evidence indicated that resveratrol supplementation may promote glucose metabolism, improve renal function, protect endothelial health, enhance working memory, improve hepatic steatosis, lower hormones, and reduce inflammation”
  4. HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in HS and TM, GL-CHPB-1-012 Rev. No. 001 (October 2025), clause 1.3 + Annexes A and B · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list [resveratrol, Polygonum/Reynoutria/Fallopia japonica and Vitis vinifera not listed in Annex A or B]”
  5. iHerb Singapore — Resveratrol category, default order (1 - 48 of 145 results) · read 2026-08-27
    what it says
    “California Gold Nutrition, Resveratrol Complex with Grape Seed Extract … trans-Resveratrol, 200 mg … Thorne, ResveraCel® … Life Extension, Optimized Resveratrol Elite™ … ProHealth Longevity, Trans-Resveratrol Plus … Doctor's Best, Trans-Resveratrol 600, 600 mg”
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Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.