Quetiapine
Medication
atypical antipsychotic
mental health
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
HealthHub: schizophrenia, bipolar or depression symptoms
When to take
HealthHub: with or without food; xr swallowed whole
Take with
Water · HealthHub: alcohol and grapefruit are avoided
Pros & cons
Pros
- HealthHub: for schizophrenia and bipolar symptoms
- HealthHub: may be taken with or without food
- Hh: also used with other medicines for low mood
Cons
- Hh: drowsiness, dizziness, dry mouth, weight gain
- HealthHub: can worsen blood sugar control in diabetes
- Hh: rare movement, heart-rhythm and blood problems
Sources
- HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
what it says
“All 26 registered quetiapine products carry 'Prescription Only' — SEROQUEL TABLET 25/100/200/300 mg · Seroquel XR 50–400 mg · Ketipinor · Quetiapine Sandoz · APO-QUETIAPINE · SQURO XR · SAQUIN SR · EVIPSYZED”
- HealthHub (National Medication Information workgroup, SG) — Quetiapine: what is this medication for · read 2026-08-27
what it says
“Quetiapine belongs to a class of medications known as atypical (second-generation) antipsychotics. It is used to treat and prevent the return of symptoms in Schizophrenia and other mental health related conditions … bipolar disorder … symptoms of depression”
- HealthHub — Quetiapine: how should I take this medication · read 2026-08-27
what it says
“Quetiapine may be taken with or without food. If you are taking Quetiapine XR (extended-release) tablet, swallow the tablet whole. Do not split, crush or chew the tablet.”
- HealthHub — Quetiapine: common side effects · read 2026-08-27
what it says
“Drowsiness or feeling tired … Nausea, vomiting … Constipation … Dizziness … Dry mouth … Increase in appetite, weight gain. Most of the side effects listed here will improve with time.”
- HealthHub — Quetiapine: what precautions should I take · read 2026-08-27
what it says
“You have diabetes. Quetiapine may sometimes worsen blood sugar control in diabetes … Blood disorders, irregular heartbeat or heart problems; kidney, liver or thyroid disease, breast cancer, stroke … seizures (fits), dementia, history of blood clots, Parkinson's disease”
- HealthHub — Quetiapine: rare but serious side effects · read 2026-08-27
what it says
“Confusion, high fever, severe muscle stiffness, irregular blood pressure (signs and symptoms of neuroleptic malignant syndrome) … Uncontrollable movements … (tardive dyskinesia) … prolonged QTc interval … symptoms of blood dyscrasias”
- HealthHub — Quetiapine: what food or medication should I avoid · read 2026-08-27
what it says
“Avoid drinking alcohol while taking Quetiapine as it can cause excessive sleepiness. Avoid grapefruit juice/products while taking Quetiapine, as the amount of Quetiapine in the body may be increased”
- HealthHub — Quetiapine: important warning for people under 25 · read 2026-08-27
what it says
“In some cases, particularly in young people below the age of 25 years, this medication may cause … New or worsening thoughts of harming yourself or ending your life; Worsening agitation, restlessness, violent behaviour”
- US FDA label for SEROQUEL (quetiapine fumarate), Table 1 Recommended Dosing, via openFDA (AstraZeneca, effective 2025-01-22) · read 2026-08-27
what it says
“Indication Initial Dose Recommended Dose Maximum Dose Schizophrenia - Adults 25 mg twice daily 150-750 mg/day 750 mg/day Schizophrenia - Adolescents (13-17 years) 25 mg twice daily 400-800 mg/day 800 mg/day”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.