← All medications

Progesterone

Medication progestogen hormonal
Aka: micronised progesterone, Utrogestan
Brands seen in Singapore: Crinone, Cyclogest, Utrogestan, Endometrin, Injesta
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
SG label: progesterone-deficit disorders; hrt with estrogen
When to take
NHS (hrt): often days 15–26 of a 28-day cycle
Take with
NHS: at bedtime, at least 2 hours after food, with water
Pros & cons
Pros
  • SG label: 100 mg and 200 mg capsules registered in SG
  • SG label: vaginal route is an alternative to oral
  • NHS: one extra dose is unlikely to harm you
Cons
  • SG label: contraindicated in thromboembolic disorders
  • SG label: not for undiagnosed vaginal bleeding
  • NHS: st john's wort may stop it working as well
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 27 Aug 2026 · read 2026-08-27
    what it says
    “CRINONE VAGINAL GEL 8% SIN10884P; CYCLOGEST PESSARY 400 mg SIN03626P; UTROGESTAN CAPSULE 200mg SIN15475P; UTROGESTAN 100 mg SIN11437P; ENDOMETRIN 100 MG SIN15005P; INJESTA 100/200MG — ATC G03DA04, all 7 progesterone rows Prescription Only”
  2. MOH National Drug Formulary (Singapore) — UTROGESTAN CAPSULE 200MG [SIN15475P], product information · read 2026-08-27
    what it says
    “MICRONISED PROGESTERONE - 200 MG … Registration Number SIN15475P … Forensic Classification PRESCRIPTION ONLY MEDICINES … ATC code G03DA04 … Prescription-only Medicines with Exemptions for Supply without Prescription NA”
  3. MOH National Drug Formulary (Singapore) — UTROGESTAN [SIN15475P], Indication · read 2026-08-27
    what it says
    “Disorders related to progesterone deficit … therapy of menopause (adjunctive use with estrogen in post-menopausal women for prevention of endometrial hyperplasia) … the vaginal route represents an alternative to the oral route”
  4. MOH National Drug Formulary (Singapore) — UTROGESTAN [SIN15475P], Recommended Dosage · read 2026-08-27
    what it says
    “the daily dose is 200mg to 300 mg divided into one or two intakes … In some cases, notably to help pregnancy, the doctor may increase the dose to 600 mg per day, divided into three intakes”
  5. MOH National Drug Formulary (Singapore) — UTROGESTAN [SIN15475P], Contraindications · read 2026-08-27
    what it says
    “Severe hepatic dysfunction. Undiagnosed vaginal bleeding. Known missed abortion or ectopic pregnancy. Mammary or genital tract carcinoma. Thromboembolic or thrombophlebitis disorders. Cerebral haemorrhage. Porphyria”
  6. NHS medicines A–Z — Utrogestan (micronised progesterone), how and when to take it (reviewed 2026) · read 2026-08-27
    what it says
    “The usual dose of Utrogestan is 2 capsules (200mg) taken once a day, on days 15 to 26 of your 28-day HRT cycle … Take Utrogestan at bedtime, at least 2 hours after food”
  7. NHS medicines A–Z — Utrogestan (micronised progesterone), if you take too much · read 2026-08-27
    what it says
    “Taking an extra dose of Utrogestan is unlikely to harm you. You may feel drowsy, dizzy, sleepy or tired”
  8. NHS medicines A–Z — Taking Utrogestan with other medicines and herbal supplements · read 2026-08-27
    what it says
    “epilepsy medicines such as phenytoin or carbamazepine … medicines for HIV, such as ritonavir … rifampicin … ciclosporin … antifungal medicines such as ketoconazole or terbinafine … warfarin … St John's wort may stop Utrogestan from working as well”
Report a correction View as JSON

Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.