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Pregabalin

Medication anticonvulsant / neuropathic agent otherpain & fever
Aka: Lyrica
Brands seen in Singapore: Lyrica, Regadex, Epibalin, Prega, Rewisca
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for seizures, nerve pain or anxiety
When to take
HealthHub: with or without food, capsule swallowed whole
Take with
Water · HealthHub: alcohol can cause excessive drowsiness
Pros & cons
Pros
  • HealthHub: for nerve pain as well as seizures
  • HealthHub: with or without food
  • NHS: usually safe with other medicines
Cons
  • HealthHub: dizziness, drowsiness, unsteady walking
  • HealthHub: rare mood or behaviour changes early on
  • HealthHub: abrupt stopping may worsen the condition
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 63 registered pregabalin products carry Forensicclassification 'Prescription Only' — SIN13094P Lyrica Capsule 25mg · SIN15775P REGADEX · SIN15724P EPIBALIN · SIN16317P PREGA · SIN15655P REWISCA; strengths 25 mg to 300 mg”
  2. HealthHub (National Medication Information workgroup, SG) — Pregabalin: what is this medication for · read 2026-08-27
    what it says
    “Pregabalin is used to control seizures (fits) and other conditions related to the nervous system. It can also be used for neuropathic (nerve) pain.”
  3. HealthHub — Pregabalin: how should I take this medication · read 2026-08-27
    what it says
    “You can take this medication with or without food. Swallow the capsule whole with water … Stopping your medication without informing your healthcare professional may cause your condition to worsen quickly.”
  4. HealthHub — Pregabalin: common side effects · read 2026-08-27
    what it says
    “The common side effects of Pregabalin include: Dizziness, drowsiness, fatigue, unsteadiness in walking … Blurred vision … Constipation … Dry mouth … Nausea, vomiting … Headache … Increased appetite … Swelling of the body”
  5. HealthHub — Pregabalin: rare but serious side effects · read 2026-08-27
    what it says
    “In rare cases, this medication may cause the following changes to a person's mental condition, especially in the first few weeks of treatment or during dose changes: Worsening agitation, restlessness, violent behaviour”
  6. HealthHub — Pregabalin: what precautions should I take · read 2026-08-27
    what it says
    “Liver, kidney, heart problems; Diabetes; History of alcoholism; History of drug dependence or abuse; Drug allergies … Be careful when driving or operating machinery as this medication may cause drowsiness or dizziness.”
  7. HealthHub — Pregabalin: what food or medication should I avoid · read 2026-08-27
    what it says
    “Avoid drinking alcohol while taking this medication as it can cause excessive drowsiness.”
  8. NHS Medicines A-Z — Pregabalin (index page) · read 2026-08-27
    what it says
    “Pregabalin - Brand names: Alzain, Axalid, Lyrica, Misabri. Find out how pregabalin treats epilepsy, anxiety and nerve pain and how to take it.”
  9. NHS Medicines A-Z — Taking pregabalin with other medicines and herbal supplements · read 2026-08-27
    what it says
    “It's usually safe to take pregabalin with other medicines … strong opioid painkillers such as morphine, codeine or oxycodone; medicines that make you feel sleepy or dizzy – pregabalin can make these side effects worse”
  10. US FDA label for LYRICA (pregabalin), section 2 Dosage and Administration, via openFDA (Parke-Davis/Pfizer, effective 2020-06-15) · read 2026-08-27
    what it says
    “Recommended Dosage for Adults and Pediatric Patients 1 Month and Older … Recommended Initial Dosage Recommended Maximum Dosage … Adults (17 years and older) 150 mg/day 600 mg/day 2 or 3 divided doses”
  11. US FDA label for LYRICA, section 2.2 Neuropathic Pain Associated with Diabetic Peripheral Neuropathy in Adults, via openFDA · read 2026-08-27
    what it says
    “The maximum recommended dose of LYRICA is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min.”
  12. US FDA label for LYRICA, Highlights dosing-recommendations table, via openFDA · read 2026-08-27
    what it says
    “Dosing recommendations: INDICATION Dosing Regimen Maximum Dose … PHN 2 or 3 divided doses per day 300 mg/day within 1 week. Maximum dose of 600 mg/day … Fibromyalgia … Maximum dose of 450 mg/day.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.