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Prazosin

Medication alpha-1 blocker heart & blood pressure
Aka: Minipress
Brands seen in Singapore: Apo-Prazo, Minison, Atodel
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
High blood pressure · HealthHub notes other uses too
When to take
HealthHub: dizziness is likeliest on starting or a rise
Take with
With or without food · alcohol raises dizziness
Pros & cons
Pros
  • HealthHub: widens blood vessel walls to lower pressure
  • HealthHub: taken with or without food
  • Three SG brands: apo-prazo, minison and atodel
Cons
  • Dizziness, light-headedness or fainting are common
  • HealthHub: drowsiness may affect focus and driving
  • Floppy iris can complicate cataract surgery
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; read from the cached copy at /tmp/hsa_all.json and filtered locally, not re-fetched · read 2026-08-27
    what it says
    “APO-PRAZO TABLET 1/2/5 mg SIN07264P, SIN07260P, SIN07263P; MINISON TABLET 1MG SIN16122P; ATODEL 1 TABLET 1 mg SIN07529P — all 5 prazosin rows read Prescription Only, ATC C02CA01. No row named Minipress.”
  2. MOH National Drug Formulary (Singapore) — APO-PRAZO TABLET 1 MG [SIN07264P], product information (no indication or dosing section is published for this product) · read 2026-08-27
    what it says
    “PRAZOSIN HCL EQV PRAZOSIN - 1 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code C02CA01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA”
  3. MOH National Drug Formulary (Singapore) — MINISON TABLET 1MG [SIN16122P], product information · read 2026-08-27
    what it says
    “PRAZOSIN HYDROCHLORIDE EQV PRAZOSIN - 1 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code C02CA01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA”
  4. MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Indication(s) · read 2026-08-27
    what it says
    “Prazosin is indicated for the treatment of hypertension.”
  5. MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Dosage and Administration · read 2026-08-27
    what it says
    “small increases should be continued until the desired effect is achieved or a total daily dosage of 20mg is reached … increased gradually to a maximum total daily dosage of 20mg given in divided doses”
  6. HealthHub (MOH Singapore) — Prazosin, medication information leaflet, uses (article last reviewed 2 April 2025) · read 2026-08-27
    what it says
    “Prazosin belongs to a group of medications known as alpha-1 blockers. It is used to reduce high blood pressure in people with hypertension. It works by widening (relaxing) blood vessel walls thus lowering your blood pressure.”
  7. HealthHub (MOH Singapore) — Prazosin, administration · read 2026-08-27
    what it says
    “Do not stop taking your medication without checking with your healthcare professional. You may take this medication with or without food.”
  8. HealthHub (MOH Singapore) — Prazosin, precautions · read 2026-08-27
    what it says
    “You are pregnant, planning to become pregnant, or breastfeeding. You have heart problems (e.g. chest pain / angina). You have kidney problems.”
  9. HealthHub (MOH Singapore) — Prazosin, common side effects · read 2026-08-27
    what it says
    “Dizziness, light-headedness or fainting … especially when you are taking Prazosin for the first time, restarting treatment, or taking a higher dose … Drowsiness — May affect your level of focus or ability to drive and use machinery.”
  10. HealthHub (MOH Singapore) — Prazosin, food and medication to avoid · read 2026-08-27
    what it says
    “Avoid drinking alcohol as it may increase the risk of dizziness, light-headedness or drowsiness. This medication may interact with other medications. Examples include: Sildenafil, Tadalafil or Vardenafil”
  11. HealthHub (MOH Singapore) — Prazosin, uses: other conditions · read 2026-08-27
    what it says
    “This medication may also be used for other conditions. Check with your healthcare professional if you are unsure why you are given this medication.”
  12. HealthHub (MOH Singapore) — Prazosin, precautions: cataract surgery · read 2026-08-27
    what it says
    “You are undergoing eye surgery for cataracts (cloudiness of the lens) … The pupil may dilate poorly and the iris (the coloured part of the eye) may become floppy during the operation.”
  13. MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Dosage and Administration: patients on other antihypertensive therapy · read 2026-08-27
    what it says
    “Because some additive effect is anticipated, the dosage level of other agents (e.g. beta-adrenergic blocking agents, methyldopa, reserpine, clonidine, etc.) should be reduced and prazosin hydrochloride initiated at 0.5mg at bedtime”
  14. MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Dosage and Administration: moderate to severe renal impairment · read 2026-08-27
    what it says
    “Because some patients in this category have responded to small doses of prazosin hydrochloride, it is recommended that therapy be initiated at 0.5mg daily and that dosage increases be instituted with caution.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.