{"ok":true,"entry":{"slug":"prazosin","kind":"medication","name":"prazosin","aliases":["Minipress"],"brands_sg":["Apo-Prazo","Minison","Atodel"],"class":"alpha-1 blocker","tags":["heart-bp"],"use_for":"high blood pressure · healthhub notes other uses too","use_after":"healthhub: dizziness is likeliest on starting or a rise","use_duration":null,"take_with":"with or without food · alcohol raises dizziness","pros":["healthhub: widens blood vessel walls to lower pressure","healthhub: taken with or without food","three sg brands: apo-prazo, minison and atodel"],"cons":["dizziness, light-headedness or fainting are common","healthhub: drowsiness may affect focus and driving","floppy iris can complicate cataract surgery"],"dose_note":"the sg label for minison states the hypertension ceiling as \"a total daily dosage of 20mg\": increases are continued \"until the desired effect is achieved or a total daily dosage of 20mg is reached\", and the dose is raised gradually \"to a maximum total daily dosage of 20mg given in divided doses\" — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["heart problems such as chest pain or angina — healthhub precaution","kidney problems — healthhub precaution; the minison label starts renal impairment lower","cataract surgery — healthhub asks that the eye specialist be told, as the iris may go floppy","pregnancy, planning pregnancy or breastfeeding — healthhub precaution"],"clashes":[{"src":["hh_prazosin_food"],"note":"healthhub names these as medications prazosin may interact with","with":"sildenafil, tadalafil or vardenafil"},{"src":["hh_prazosin_food"],"food":true,"note":"healthhub: may increase the risk of dizziness, light-headedness or drowsiness","with":"alcohol"},{"src":["ndf_minison_add"],"note":"minison label: some additive effect is anticipated, so other agents are reduced and prazosin restarted low","with":"diuretics and other antihypertensives"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; read from the cached copy at /tmp/hsa_all.json and filtered locally, not re-fetched","quote":"APO-PRAZO TABLET 1/2/5 mg SIN07264P, SIN07260P, SIN07263P; MINISON TABLET 1MG SIN16122P; ATODEL 1 TABLET 1 mg SIN07529P — all 5 prazosin rows read Prescription Only, ATC C02CA01. No row named Minipress.","accessed":"2026-08-27"},{"id":"ndf_apoprazo","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin07264p/","label":"MOH National Drug Formulary (Singapore) — APO-PRAZO TABLET 1 MG [SIN07264P], product information (no indication or dosing section is published for this product)","quote":"PRAZOSIN HCL EQV PRAZOSIN - 1 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code C02CA01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA","accessed":"2026-08-27"},{"id":"ndf_minison","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16122p/","label":"MOH National Drug Formulary (Singapore) — MINISON TABLET 1MG [SIN16122P], product information","quote":"PRAZOSIN HYDROCHLORIDE EQV PRAZOSIN - 1 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code C02CA01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA","accessed":"2026-08-27"},{"id":"ndf_minison_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16122p/","label":"MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Indication(s)","quote":"Prazosin is indicated for the treatment of hypertension.","accessed":"2026-08-27"},{"id":"ndf_minison_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16122p/","label":"MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Dosage and Administration","quote":"small increases should be continued until the desired effect is achieved or a total daily dosage of 20mg is reached … increased gradually to a maximum total daily dosage of 20mg given in divided doses","accessed":"2026-08-27"},{"id":"hh_prazosin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, medication information leaflet, uses (article last reviewed 2 April 2025)","quote":"Prazosin belongs to a group of medications known as alpha-1 blockers. It is used to reduce high blood pressure in people with hypertension. It works by widening (relaxing) blood vessel walls thus lowering your blood pressure.","accessed":"2026-08-27"},{"id":"hh_prazosin_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, administration","quote":"Do not stop taking your medication without checking with your healthcare professional. You may take this medication with or without food.","accessed":"2026-08-27"},{"id":"hh_prazosin_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, precautions","quote":"You are pregnant, planning to become pregnant, or breastfeeding. You have heart problems (e.g. chest pain / angina). You have kidney problems.","accessed":"2026-08-27"},{"id":"hh_prazosin_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, common side effects","quote":"Dizziness, light-headedness or fainting … especially when you are taking Prazosin for the first time, restarting treatment, or taking a higher dose … Drowsiness — May affect your level of focus or ability to drive and use machinery.","accessed":"2026-08-27"},{"id":"hh_prazosin_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, food and medication to avoid","quote":"Avoid drinking alcohol as it may increase the risk of dizziness, light-headedness or drowsiness. This medication may interact with other medications. Examples include: Sildenafil, Tadalafil or Vardenafil","accessed":"2026-08-27"},{"id":"hh_prazosin_other","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, uses: other conditions","quote":"This medication may also be used for other conditions. Check with your healthcare professional if you are unsure why you are given this medication.","accessed":"2026-08-27"},{"id":"hh_prazosin_eye","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prazosin","label":"HealthHub (MOH Singapore) — Prazosin, precautions: cataract surgery","quote":"You are undergoing eye surgery for cataracts (cloudiness of the lens) … The pupil may dilate poorly and the iris (the coloured part of the eye) may become floppy during the operation.","accessed":"2026-08-27"},{"id":"ndf_minison_add","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16122p/","label":"MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Dosage and Administration: patients on other antihypertensive therapy","quote":"Because some additive effect is anticipated, the dosage level of other agents (e.g. beta-adrenergic blocking agents, methyldopa, reserpine, clonidine, etc.) should be reduced and prazosin hydrochloride initiated at 0.5mg at bedtime","accessed":"2026-08-27"},{"id":"ndf_minison_renal","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16122p/","label":"MOH National Drug Formulary (Singapore) — MINISON [SIN16122P], Dosage and Administration: moderate to severe renal impairment","quote":"Because some patients in this category have responded to small doses of prazosin hydrochloride, it is recommended that therapy be initiated at 0.5mg daily and that dosage increases be instituted with caution.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}