Pomegranate
Supplement
botanical
heart & metabolicskin & hair
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Blood-pressure and glucose signals; one 4-week skin trial
Studied for
The skin trial ran four weeks
Pros & cons
Pros
- NCCIH: juice or extract may reduce blood pressure
- NCCIH: a small reduction in blood glucose is reported
- A 4-week RCT cut wrinkle severity against placebo
Cons
- NCCIH: more research is needed to confirm the bp effect
- No clear effect on cholesterol or other lipids
- HSA prohibits stem bark and root bark in supplements
Sources
- NCCIH — Pomegranate: What You Need To Know (last updated April 2025) · read 2026-08-27
what it says
“Pomegranate juice or extract may be helpful in reducing blood pressure, but additional research is needed … may reduce blood glucose levels to a small extent … no clear effects have been demonstrated [on lipids]”
- Prospective Randomized Double-Blind Placebo-Controlled Study of Oral Pomegranate Extract on Skin Wrinkles, Biophysical Features, and the Gut-Skin Axis (Chakkalakal et al., J Clin Med 2022) · read 2026-08-27
what it says
“Subjects were supplemented with a standardized punicalagin enriched oral pomegranate extract … or a placebo … daily for four weeks … The PE group had significant reductions in wrinkle severity (p < 0.01)”
- HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025), Annex A and Annex B — read from the cached PDF text on disk · read 2026-08-27
what it says
“87. Punica granatum (stem bark and root bark) — Prohibited in HS — Absence of pomegranate alkaloids … Restricted use in TM: "Not suitable for long term use. Seek medical advice if needed."”
- HSA — Health Supplements Guidelines, GL-CHPB-3-001 Rev. No. 020 (January 2026), Tables 4 and 5 (vitamins and minerals limits) — read from the cached PDF text on disk · read 2026-08-27
what it says
“HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
- HSA — Health Supplements Guidelines (January 2026), Table 6: examples of diseases/conditions/disorders not allowed for health supplements · read 2026-08-27
what it says
“Blood and circulatory system: Hypertension, stroke, cholesterol disorders, reduces cholesterol … Endocrine system: Diabetes … Skin, hair and nails: … pigmentation disorders, alopecia”
- iHerb Singapore — Pomegranate Extract category (default order, 1 - 28 of 28 results) · read 2026-08-27
what it says
“Source Naturals, Pomegranate Extract, 500 mg, 240 Tablets … Life Extension, Pomegranate Complete … Thorne, Hormone Advantage … Life Extension, Pomegranate Fruit Extract … Navitas Organics, Organic Pomegranate Powder … Swanson Vitamins, Full Spectrum Pomegranate”
Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.