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Pantoprazole

Medication proton pump inhibitor digestive
Aka: Controloc, Pantotab
Brands seen in Singapore: Controloc, Pantotab, Peptazol, Pantin, Pantonex
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for reflux, heartburn or stomach ulcers
When to take
NHS: usually once a day, first thing in the morning
Take with
Water · HealthHub: half to one hour before food
Pros & cons
Pros
  • NHS: usually one tablet a day
  • NHS: no common side effects listed
  • HealthHub: generally well-tolerated
Cons
  • NHS: uncommon headache, diarrhoea, nausea, constipation
  • HealthHub: rare low magnesium; long use, low B12
  • NHS: not usually recommended in pregnancy
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered offline) · read 2026-08-27
    what it says
    “All 20 registered pantoprazole products carry Forensicclassification 'Prescription Only' — SIN08843P CONTROLOC TABLET 40 mg · SIN15863P PANTOTAB · SIN12452P PEPTAZOL 40 · SIN15041P PANTIN 40 · SIN14467P PANTONEX DR-40”
  2. NHS Medicines A-Z — Pantoprazole: about pantoprazole · read 2026-08-27
    what it says
    “Pantoprazole is a proton pump inhibitor (PPI) you can get on prescription or from a pharmacy. It's used for heartburn, acid reflux and stomach ulcers.”
  3. NHS Medicines A-Z — Pantoprazole: dosage and how to take it · read 2026-08-27
    what it says
    “The usual dose to treat: heartburn and acid reflux is 20mg a day … stomach ulcers is 40mg a day … Zollinger-Ellison syndrome is 80mg a day at first – this can increase to 160mg a day”
  4. NHS Medicines A-Z — Pantoprazole: side effects · read 2026-08-27
    what it says
    “There are no common side effects with this medicine. Uncommon side effects that happen in less than 1 in 100 people include headaches, diarrhoea, feeling or being sick, constipation, a dry mouth or feeling tired.”
  5. NHS Medicines A-Z — Pantoprazole: who can and cannot take it · read 2026-08-27
    what it says
    “tell your doctor if you: have ever had an allergic reaction to pantoprazole … have liver problems … are pregnant, trying to get pregnant or breastfeeding … are due to have an endoscopy … have low levels of vitamin B12”
  6. NHS Medicines A-Z — Pantoprazole: pregnancy, breastfeeding and fertility · read 2026-08-27
    what it says
    “Pantoprazole is not usually recommended because there is very little information about its use during pregnancy. Your doctor may recommend a similar medicine called omeprazole instead as there is more safety information available.”
  7. NHS Medicines A-Z — Pantoprazole: taking it with other medicines and herbal supplements · read 2026-08-27
    what it says
    “antifungal medicines such as itraconazole, posaconazole or voriconazole; methotrexate … HIV medicines; rifampicin, an antibiotic; medicines that help to prevent blood clots, such as warfarin”
  8. HealthHub (National Medication Information workgroup, SG) — Pantoprazole: what is this medication for · read 2026-08-27
    what it says
    “Pantoprazole is used to treat and prevent acid regurgitation … / gastroesophageal reflux disease or heartburn. It is also used to treat ulcers in the digestive tract or prevent ulcers caused by Non-Steroidal Anti-inflammatory (NSAID) drugs.”
  9. HealthHub — Pantoprazole: how should I take or use this medication · read 2026-08-27
    what it says
    “Tablets should not be crushed or chewed and should be swallowed whole with water. Takes this medication half to one hour before food.”
  10. HealthHub — Pantoprazole: common and rare side effects · read 2026-08-27
    what it says
    “Pantoprazole is generally well-tolerated … Rarely pantoprazole may cause low magnesium levels in the blood … Long term use of pantoprazole may lead to vitamin B12 deficiency which may result in fatigue and numbness.”
  11. HealthHub — Pantoprazole: what food or medication should I avoid · read 2026-08-27
    what it says
    “Pantoprazole may interact with some medicines used to treat Human Immunodeficiency Virus (HIV) e.g. atazanavir and rilpivirine … methotrexate … itraconazole, ketoconazole, posaconazole (antifungal medication)”
  12. US FDA label for PROTONIX (pantoprazole sodium) delayed-release, section 2 Dosage and Administration, via openFDA drug/label.json (effective 2026-05-18) · read 2026-08-27
    what it says
    “Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome Adults 40 mg Twice daily … Doses up to 240 mg daily have been administered.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.