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Panax notoginseng

Supplement botanical heart & metabolic
Aka: tienchi, san qi, Panax notoginseng, pseudoginseng
Brands seen in Singapore: California Gold Nutrition, Swanson Vitamins, NOW Foods, Imperial Elixir, Nutricost
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Traditional use for bleeding, bruising and blood stasis
When to take
Trial schedule was twice daily
Studied for
The trial ran 3 months, in patients
Pros & cons
Pros
  • A 2,966-patient trial tested oral saponins vs placebo
  • Serious adverse events matched placebo in that trial
  • Long recorded use for bleeding and swelling
Cons
  • That trial was in stroke patients, not healthy adults
  • With warfarin: raised INR and bruising reported
  • SG labels cannot claim stroke or clotting benefits
Sources
  1. A narrative review of Panax notoginseng: Unique saponins and their pharmacological activities (Li, Shi & Wu, J Ginseng Res 2025) · read 2026-08-27
    what it says
    “Panax notoginseng (PN) is a precious traditional Chinese medicine (TCM) whose medicinal parts are roots and rhizomes for the treatment of haemorrhage, blood-stasis, swelling and pain.”
  2. Efficacy and Safety of Panax notoginseng Saponins in the Treatment of Adults With Ischemic Stroke in China: A Randomized Clinical Trial (JAMA Network Open 2023) · read 2026-08-27
    what it says
    “Eligible patients were randomly assigned … to receive either Xuesaitong soft capsules (120 mg orally twice daily) or placebo … for 3 months … serious adverse events occurred in 15 of 1488 patients (1.0%) … and 16 of 1482 (1.1%)”
  3. Interaction Between Chinese Medicine and Warfarin: Clinical and Research Update (Front Pharmacol 2021) — notoginseng section · read 2026-08-27
    what it says
    “Therefore, Panax notoginseng combined with warfarin may cause increased INR and multiple subcutaneous hemorrhage and ecchymosis.”
  4. Front Pharmacol 2021 warfarin review — recorded pharmacology of Panax notoginseng (Sanqi) · read 2026-08-27
    what it says
    “has the effects of removing blood stasis, stopping bleeding, promoting blood circulation and relieving pain. Modern pharmacological effects include hemostasis (promoting blood clotting), anti-thrombosis, promoting hematopoiesis, inhibiting the heart, expanding blood vessels, and lowering blood pressure.”
  5. HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025), Annex A (118 rows) and Annex B (4 rows) — panax notoginseng / tienchi / san qi / pseudoginseng NOT LISTED in either annex · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  6. HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. No. 020 (January 2026), clause 6.6 and Table 6 (prohibited claims) — Blood and circulatory system row: Hypertension, stroke, cholesterol disorders, reduces cholesterol, regulates platelet aggregation, coagulation defects, arteriosclerosis · read 2026-08-27
    what it says
    “HS must not be labelled, advertised or promoted for any specific medicinal purpose, i.e. treatment or prevention, implied or otherwise, of any disease or disorder … Blood and circulatory system: Hypertension, stroke … regulates platelet aggregation, coagulation defects, arteriosclerosis”
  7. HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. No. 020 (January 2026), clause 4.8 with Tables 4-5 (vitamins and minerals only — no botanical rows) · read 2026-08-27
    what it says
    “4.8 HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
  8. iHerb Singapore — Ginseng category page, default listing order · read 2026-08-27
    what it says
    “1 - 48 of 101 results … California Gold Nutrition, Panax Ginseng Extract … Swanson Vitamins, Korean Red Ginseng … NOW Foods, Panax Ginseng … Imperial Elixir, Royal Jelly … Nutricost, Korean Red Ginseng … Imperial Elixir, Tienchi Ginseng”

Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.