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Oxycodone

Medication opioid analgesic pain & fever
Aka: OxyContin, OxyNorm
Brands seen in Singapore: OxyContin, OxyNorm, Oxycodone Wockhardt, Oxycodone Kalceks
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for severe pain, e.g. after surgery or in cancer
When to take
NHS: with or without food; long-acting types less often
Take with
Water · NHS: no grapefruit juice; alcohol adds sleepiness
Pros & cons
Pros
  • NHS: for pain when paracetamol or ibuprofen fail
  • Hh: capsules, prolonged-release tablets and solution
  • HSA: 9 registered products, all prescription only
Cons
  • NHS: constipation, nausea and drowsiness are common
  • HealthHub: it has the potential to cause addiction
  • NHS: stopping suddenly can cause withdrawal symptoms
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 9 registered oxycodone products carry Forensicclassification 'Prescription Only' — SIN14885P OXYCONTIN NEO 20 MG · SIN13083P OXYNORM 5MG CAPSULE · SIN15996P OXYCODONE WOCKHARDT · SIN16635P OXYCODONE KALCEKS · SIN14032P TARGIN (with naloxone)”
  2. NHS Medicines A-Z — Oxycodone: what oxycodone is for · read 2026-08-27
    what it says
    “Oxycodone is a medicine used to treat severe pain. It's only available with a prescription … It's often used for moderate to severe pain when other painkillers, such as paracetamol and ibuprofen, have not worked.”
  3. NHS Medicines A-Z — Oxycodone: how to take oxycodone · read 2026-08-27
    what it says
    “Oxycodone usually comes as tablets, capsules and a liquid you swallow. There are some long-acting (prolonged release) tablets that work in a different way and are taken less often … take it with or without food”
  4. NHS Medicines A-Z — Oxycodone: side effects · read 2026-08-27
    what it says
    “Common side effects of oxycodone include: constipation; feeling sick (nausea) or being sick (vomiting); feeling sleepy or tired; feeling dizzy; confusion; headaches; itchy skin or rash”
  5. NHS Medicines A-Z — Oxycodone: who can and cannot take it, breastfeeding · read 2026-08-27
    what it says
    “it may not be suitable if: you have a liver or kidney condition; you have a lung condition, such as asthma; you have ever had an addiction to alcohol, prescription medicines or recreational drugs”
  6. NHS Medicines A-Z — Oxycodone: taking it with other medicines · read 2026-08-27
    what it says
    “other opioid painkillers such as codeine and co-codamol; medicines for mental health conditions such as depression or anxiety; medicines to control seizures or fits such as gabapentin or pregabalin; the herbal supplement St John's wort”
  7. NHS Medicines A-Z — Oxycodone: food, drink and alcohol · read 2026-08-27
    what it says
    “Do not drink grapefruit juice while taking oxycodone. It's also best not to drink alcohol because it can make you feel sleepy and increase the risk of serious side effects.”
  8. NHS Medicines A-Z — Oxycodone: how to stop taking oxycodone · read 2026-08-27
    what it says
    “Do not stop taking it suddenly because this can cause withdrawal symptoms … It's possible to become addicted to oxycodone. Your doctor will make sure you're only taking the amount you need to control your pain.”
  9. HealthHub (National Medication Information workgroup, SG) — Oxycodone: what is this medication for · read 2026-08-27
    what it says
    “This medication is used to treat severe pain. It belongs to a class of drug known as opioids … Oxycodone capsules; Oxycodone prolonged release tablets; Oxycodone oral solution … taken with or after food.”
  10. HealthHub — Oxycodone: common side effects and addiction potential · read 2026-08-27
    what it says
    “This medication has the potential to cause addiction. If you experience difficulty stopping this medication when it is no longer required, or find yourself using more than the recommended dose … consult your healthcare professional.”
  11. HealthHub — Oxycodone: what precautions should I take · read 2026-08-27
    what it says
    “You have a history of fits. This drug may increase the risk of having a fit. You have a history of constipation or obstructive bowel disease. You have a history of lung disease including asthma”
  12. US FDA label for OXYCONTIN (oxycodone HCl extended-release tablets), section 2 Dosage and Administration, via openFDA (Knoa Pharma, effective 2026-06-24) · read 2026-08-27
    what it says
    “OXYCONTIN 60 mg and 80 mg tablets, a single dose greater than 40 mg, or a total daily dose greater than 80 mg are only for use in patients in whom tolerance … has been established.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.