{"ok":true,"entry":{"slug":"oxycodone","kind":"medication","name":"oxycodone","aliases":["OxyContin","OxyNorm"],"brands_sg":["OxyContin","OxyNorm","Oxycodone Wockhardt","Oxycodone Kalceks"],"class":"opioid analgesic","tags":["pain-fever"],"use_for":"prescribed for severe pain, e.g. after surgery or in cancer","use_after":"nhs: with or without food; long-acting types less often","use_duration":null,"take_with":"water · nhs: no grapefruit juice; alcohol adds sleepiness","pros":["nhs: for pain when paracetamol or ibuprofen fail","hh: capsules, prolonged-release tablets and solution","hsa: 9 registered products, all prescription only"],"cons":["nhs: constipation, nausea and drowsiness are common","healthhub: it has the potential to cause addiction","nhs: stopping suddenly can cause withdrawal symptoms"],"dose_note":"the us fda label for oxycontin states 'OXYCONTIN 60 mg and 80 mg tablets, a single dose greater than 40 mg, or a total daily dose greater than 80 mg are only for use in patients in whom tolerance to an opioid of comparable potency has been established' and 'Use the lowest effective dosage for the shortest duration' — 80 mg a day is the ceiling that label sets for anyone not already opioid-tolerant, on that product. sg-registered oral strengths are oxycontin neo 10 mg and 20 mg prolonged-release tablets and oxynorm 5 mg and 10 mg capsules. neither healthhub nor nhs publishes a number; in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["a liver, kidney or lung condition such as asthma (nhs)","a past addiction to alcohol, medicines or drugs (nhs)","a history of fits, constipation or bowel obstruction (healthhub)","breastfeeding — nhs: not usually used"],"clashes":[{"src":["nhs_oxy_mix"],"note":"nhs lists other opioids among medicines that may not mix well","with":"other opioid painkillers (codeine, co-codamol)"},{"src":["nhs_oxy_mix"],"note":"nhs lists mental-health medicines among those that may not mix well","with":"medicines for depression or anxiety"},{"src":["nhs_oxy_mix"],"note":"nhs lists seizure medicines among those that may not mix well","with":"gabapentin or pregabalin"},{"src":["nhs_oxy_mix"],"note":"nhs lists the herbal supplement among those that may not mix well","with":"st john's wort"},{"src":["nhs_oxy_food"],"food":true,"note":"nhs: grapefruit juice is not to be drunk; alcohol raises the risk of serious side effects","with":"alcohol and grapefruit juice"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 9 registered oxycodone products carry Forensicclassification 'Prescription Only' — SIN14885P OXYCONTIN NEO 20 MG · SIN13083P OXYNORM 5MG CAPSULE · SIN15996P OXYCODONE WOCKHARDT · SIN16635P OXYCODONE KALCEKS · SIN14032P TARGIN (with naloxone)","accessed":"2026-08-27"},{"id":"nhs_oxy_about","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: what oxycodone is for","quote":"Oxycodone is a medicine used to treat severe pain. It's only available with a prescription … It's often used for moderate to severe pain when other painkillers, such as paracetamol and ibuprofen, have not worked.","accessed":"2026-08-27"},{"id":"nhs_oxy_howto","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: how to take oxycodone","quote":"Oxycodone usually comes as tablets, capsules and a liquid you swallow. There are some long-acting (prolonged release) tablets that work in a different way and are taken less often … take it with or without food","accessed":"2026-08-27"},{"id":"nhs_oxy_side","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: side effects","quote":"Common side effects of oxycodone include: constipation; feeling sick (nausea) or being sick (vomiting); feeling sleepy or tired; feeling dizzy; confusion; headaches; itchy skin or rash","accessed":"2026-08-27"},{"id":"nhs_oxy_who","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: who can and cannot take it, breastfeeding","quote":"it may not be suitable if: you have a liver or kidney condition; you have a lung condition, such as asthma; you have ever had an addiction to alcohol, prescription medicines or recreational drugs","accessed":"2026-08-27"},{"id":"nhs_oxy_mix","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: taking it with other medicines","quote":"other opioid painkillers such as codeine and co-codamol; medicines for mental health conditions such as depression or anxiety; medicines to control seizures or fits such as gabapentin or pregabalin; the herbal supplement St John's wort","accessed":"2026-08-27"},{"id":"nhs_oxy_food","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: food, drink and alcohol","quote":"Do not drink grapefruit juice while taking oxycodone. It's also best not to drink alcohol because it can make you feel sleepy and increase the risk of serious side effects.","accessed":"2026-08-27"},{"id":"nhs_oxy_stop","url":"https://www.nhs.uk/medicines/oxycodone/","label":"NHS Medicines A-Z — Oxycodone: how to stop taking oxycodone","quote":"Do not stop taking it suddenly because this can cause withdrawal symptoms … It's possible to become addicted to oxycodone. Your doctor will make sure you're only taking the amount you need to control your pain.","accessed":"2026-08-27"},{"id":"hh_oxy_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxycodone","label":"HealthHub (National Medication Information workgroup, SG) — Oxycodone: what is this medication for","quote":"This medication is used to treat severe pain. It belongs to a class of drug known as opioids … Oxycodone capsules; Oxycodone prolonged release tablets; Oxycodone oral solution … taken with or after food.","accessed":"2026-08-27"},{"id":"hh_oxy_addiction","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxycodone","label":"HealthHub — Oxycodone: common side effects and addiction potential","quote":"This medication has the potential to cause addiction. If you experience difficulty stopping this medication when it is no longer required, or find yourself using more than the recommended dose … consult your healthcare professional.","accessed":"2026-08-27"},{"id":"hh_oxy_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxycodone","label":"HealthHub — Oxycodone: what precautions should I take","quote":"You have a history of fits. This drug may increase the risk of having a fit. You have a history of constipation or obstructive bowel disease. You have a history of lung disease including asthma","accessed":"2026-08-27"},{"id":"fda_oxycontin_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22OXYCONTIN%22&limit=1","label":"US FDA label for OXYCONTIN (oxycodone HCl extended-release tablets), section 2 Dosage and Administration, via openFDA (Knoa Pharma, effective 2026-06-24)","quote":"OXYCONTIN 60 mg and 80 mg tablets, a single dose greater than 40 mg, or a total daily dose greater than 80 mg are only for use in patients in whom tolerance … has been established.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:27.496708+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}