← All medications

Ofloxacin

Medication fluoroquinolone antibiotic antibiotic
Aka: Tarivid, levofloxacin precursor
Brands seen in Singapore: Fugacin, Ofcin, Akilen, Oflox, Flovid
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
SG label: urinary, chest, skin and genital tract infections
When to take
Medlineplus: once or twice a day, doses about 12 hours apart
Take with
Water · medlineplus: 2 hours apart from antacids and iron
Pros & cons
Pros
  • Medlineplus: kills the bacteria that cause infections
  • SG label: gonorrhoea treated as a single 400 mg dose
  • SG label: oral tablets, no drip needed
Cons
  • US boxed warning: tendinitis and tendon rupture risk
  • US boxed warning: nerve damage and CNS effects
  • Medlineplus: skin can turn sensitive to sunlight
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 6 rows whose active ingredient is exactly 'OFLOXACIN' read 'Prescription Only' — FUGACIN TABLET 200 mg · OFCIN 200 mg and 400 mg · AKILEN TABLET 200 mg · OFLOX TABLET 200 mg · FLOVID 200 (all ATC J01MA01)”
  2. National Drug Formulary (SG, MOH) — OFCIN FILM COATED TABLET 400 MG [SIN10118P], approved indication and dosing · read 2026-08-27
    what it says
    “Urinary tract infections: 200 to 400mg daily … increased if necessary in upper urinary tract infections to 400mg twice daily … Uncomplicated gonorrhoea: 400mg as a single dose … contraindicated in patients with a history of epilepsy”
  3. MedlinePlus (NIH/AHFS) — Ofloxacin, including the IMPORTANT WARNING section · read 2026-08-27
    what it says
    “Ofloxacin increases the risk of tendinitis … or tendon rupture … the risk is highest in people over 60 years of age … take them 2 hours before or 2 hours after ofloxacin”
  4. US FDA label — ofloxacin tablets USP, DOSAGE AND ADMINISTRATION, via openFDA · read 2026-08-27
    what it says
    “The usual dose of ofloxacin tablets is 200 mg to 400 mg orally every 12 h … A maximum dose of 400 mg of ofloxacin per day should therefore not be exceeded [cirrhosis]”
  5. US FDA label — ofloxacin tablets USP, boxed warning, via openFDA · read 2026-08-27
    what it says
    “Fluoroquinolones, including ofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions … Tendinitis and tendon rupture Peripheral neuropathy Central nervous system effects … may exacerbate muscle weakness in … myasthenia gravis”
Report a correction View as JSON

Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.