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Nicotine

Medication nicotine replacement therapy other
Aka: Nicorette, NRT patch, nicotine gum, Nicotinell
Brands seen in Singapore: Nicorette, Nicotinell, Skiip
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Withdrawal symptoms and cravings when stopping smoking
When to take
Patch on waking, off at bedtime · gum when a craving comes
Take with
Advice and support — the SG label says they improve success
Pros & cons
Pros
  • Cochrane 2018: rr 1.55 for quitting vs control
  • Cochrane judged the evidence high quality
  • Pharmacy only in SG — no prescription needed
Cons
  • Pharmacy only — not on the open shelf in SG
  • SG label: patch off at night, sleep can be disturbed
  • SG label: regular use past 12 months not advised
Sources
  1. MOH National Drug Formulary — NICORETTE ICY MINT MEDICATED CHEWING GUM 2MG [SIN14326P], indication and dosing (page last updated 28 Jul 2026) · read 2026-08-27
    what it says
    “used to relieve withdrawal symptoms and reduce the cravings for nicotine that you get when you try to stop smoking. Advice and support normally improve the success rate … Do not exceed the following quantity in any 24-hour period: 2mg: 30 gums 4mg: 24 gums … Regular use beyond 12 months is generally not recommended”
  2. MOH National Drug Formulary — NICORETTE INVISI TRANSDERMAL PATCH 25MG/16 HOURS [SIN14296P], dosing and 'things you must not do' · read 2026-08-27
    what it says
    “Use one new patch per day. Apply when you wake up … and remove 16 hours later … Do not use more than one patch at a time … The patch should not be kept on at night while sleeping as it may cause nicotine-induced sleep disturbance … Avoid placing the patch onto any area of skin that is red, cut or irritated”
  3. MOH National Drug Formulary — NICORETTE ICY MINT MEDICATED CHEWING GUM 2MG [SIN14326P], product information fields · read 2026-08-27
    what it says
    “Active Ingredient and Strength NICOTINE RESINATE 10 MG EQUIV NICOTINE - 2 MG … Forensic Classification PHARMACY ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code N07BA01”
  4. HSA register of therapeutic products (data.gov.sg d_767279312753558cbf19d48344577084) — 18 nicotine rows, filtered locally from the cached copy on 27 Aug 26 · read 2026-08-27
    what it says
    “Nicorette Icy Mint Medicated Chewing Gum 2mg … Pharmacy Only … Nicorette Invisi Transdermal Patch 10mg/15mg/25mg/16 hours … Pharmacy Only … NICORETTE QUICKMIST MOUTHSPRAY 1MG/SPRAY … NICOTINELL TTS 10/20/30 … NICOTINELL MINT LOZENGE 1 mg … SKIIP NICOTINE MINI LOZENGE 2 MG … N07BA01”
  5. Cochrane Database of Systematic Reviews — Nicotine replacement therapy versus control for smoking cessation (Hartmann-Boyce, Chepkin, Ye, Bullen, Lancaster 2018; PMC6353172) · read 2026-08-27
    what it says
    “We identified 136 studies; 133 with 64,640 participants … We judged the evidence to be of high quality … The RR of abstinence for any form of NRT relative to control was 1.55 (95% confidence interval (CI) 1.49 to 1.61) … 1.49 … for nicotine gum; 1.64 … for nicotine patch”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.