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Stinging nettle

Supplement botanical men's health
Aka: Urtica dioica, nettle root, nettle leaf
Brands seen in Singapore: California Gold Nutrition, Frontier Co-op, Swanson Vitamins, NOW Foods, Nature's Way
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prostate symptoms in men — one small 12-week RCT
Studied for
The bph trial ran 12 weeks; the rhinitis trial one month
Pros & cons
Pros
  • 12-week RCT in 60 men: intermediate effect on ipss
  • No side effects were seen in that bph trial
  • Root is among the better-studied luts botanicals
Cons
  • The bph trial was small — 30 men per arm
  • Rhinitis trial: placebo did about as well
  • Extracts differ; one product's data may not carry over
Sources
  1. Urtica dioica root extract on clinical and biochemical parameters in patients with BPH, randomized controlled trial (Karami et al., Pak J Biol Sci 2020) · read 2026-08-27
    what it says
    “Participants were 60 men with BPH … received 450 mg day-1 UDE and placebo as tablets for 12 weeks … UDE had an intermediate effect on IPSS … No side effects were seen in these patients”
  2. Natural Products in the Treatment of Lower Urinary Tract Dysfunction and Infection (Lederer & Michel, Handb Exp Pharmacol 2025) · read 2026-08-27
    what it says
    “Most evidence for male LUTS is based on extracts from saw palmetto berries, stinging nettle roots, and pumpkin seeds … only limited information is available for most individual extracts”
  3. Natural Products in the Treatment of Lower Urinary Tract Dysfunction and Infection (Lederer & Michel, Handb Exp Pharmacol 2025) · read 2026-08-27
    what it says
    “extracts from the same plants are likely to exhibit at least quantitative differences in potential active ingredients, which makes extrapolation of findings with one extract to those of others potentially difficult”
  4. Efficacy of supportive therapy of allergic rhinitis by stinging nettle root extract: a randomized, double-blind, placebo-controlled trial (Bakhshaee et al., Iran J Pharm Res 2017) · read 2026-08-27
    what it says
    “74 patients … randomly divided into 2 groups who were taken Urtica dioica 150-mg … or placebo for one month … similar effects were demonstrated by placebo as well”
  5. A placebo-controlled, pseudo-randomized, crossover trial of botanical agents for Gulf War Illness (Younger et al., Int J Environ Res Public Health 2021) · read 2026-08-27
    what it says
    “Symptom severity was not decreased from placebo with lower-dose stinging nettle (p = 0.604), but was significantly decreased with higher-dose stinging nettle (p = 0.048) … These results are in a small sample and are preliminary”
  6. HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev 001 (Oct 2025) · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list [Urtica dioica / stinging nettle not listed in Annex A or B]”
  7. iHerb Singapore — Nettle category (default order) · read 2026-08-27
    what it says
    “California Gold Nutrition, EuroHerbs®, Nettle Root Extract … Frontier Co-op, Organic Cut & Sifted Stinging Nettle Leaf … Swanson Vitamins, Stinging Nettle Root, 500 mg … NOW Foods, Stinging Nettle Root Extract … Nature's Way, Nettle Leaf”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.