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Naproxen

Medication NSAID pain & fever
Aka: Synflex, Naprosyn, Aleve
Brands seen in Singapore: Synflex, Aleve, Soproxen, Apo-Naproxen, Sunprox
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Pain and inflammation — period, joint and muscle pain
When to take
Label: 1 tablet every 8–12 h · NHS: up to 3× a day
Take with
With or after food · swallowed whole with water (NHS)
Pros & cons
Pros
  • Longer gap between doses than most NSAIDs (8–12 h)
  • One SG pack is general sale list: aleve 220 mg (otc)
  • Eases pain and reduces inflammation (HealthHub)
Cons
  • Prescription-only in SG above the 220 mg otc pack
  • Stomach irritation and heartburn are common (HealthHub)
  • NHS: max 3 days if bought without a prescription
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, Health Sciences Authority), Forensicclassification column; all 5,511 rows pulled via the datastore_search API on 27 Aug 2026 · read 2026-08-27
    what it says
    “SYNFLEX 275 mg | SIN05621P | Prescription Only; APO-NAPROXEN, SOPROXEN, SUNPROX | Prescription Only; ALEVE TABLET 220 mg | SIN12440P | General Sale List — 12 of 13 naproxen rows Prescription Only, none Pharmacy Only; no NAPROSYN row.”
  2. MOH National Drug Formulary (Singapore) — ALEVE TABLET 220 mg (OTC Pack) [SIN12440P], naproxen sodium, Bayer (South East Asia) Pte Ltd · read 2026-08-27
    what it says
    “GENERAL SALE LIST … 1 tablet every 8 to 12 hours … Do not exceed 3 tablets in 24 hours … Maximum of 2 tablets per day … ALEVE should not be taken for more than 10 consecutive days”
  3. HealthHub (MOH Singapore) — Naproxen Oral, article last reviewed 07 July 2026 · read 2026-08-27
    what it says
    “non-steroidal anti-inflammatory drug (NSAID) … used to treat pain and reduce inflammation … best taken with meals … Avoid taking together with other NSAIDs (e.g. Ibuprofen, Diclofenac) … excessive … alcohol … increase the risk of bleeding”
  4. HealthHub (MOH Singapore) — Naproxen Oral, precautions and side effects sections · read 2026-08-27
    what it says
    “You have a history of stomach or bowel ulcers or bleeding, or bleeding problems … You have asthma … You have a history of kidney, liver, heart problems or stroke … Stomach discomfort/irritation e.g. stomach pain, heartburn”
  5. NHS medicines A–Z — Naproxen (what it is for, and who it may not suit) · read 2026-08-27
    what it says
    “relieve pain and reduce swelling (inflammation) … period pain, joint and muscle pain … a stomach ulcer … a heart, liver or kidney condition … asthma or allergies … pregnant or trying to get pregnant”
  6. NHS medicines A–Z — Naproxen (how and when to take it) · read 2026-08-27
    what it says
    “It's usually taken up to 3 times a day … swallow tablets whole with water … taken with or after food … Do not take naproxen for longer than 3 days if you bought it without a prescription”
  7. NHS medicines A–Z — Naproxen (medicines that do not mix well with it) · read 2026-08-27
    what it says
    “anticoagulants, such as warfarin … steroid medicines … antidepressants … medicines to treat heart problems and high blood pressure”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.