{"ok":true,"entry":{"slug":"naproxen","kind":"medication","name":"naproxen","aliases":["Synflex","Naprosyn","Aleve"],"brands_sg":["Synflex","Aleve","Soproxen","Apo-Naproxen","Sunprox"],"class":"NSAID","tags":["pain-fever"],"use_for":"pain and inflammation — period, joint and muscle pain","use_after":"label: 1 tablet every 8–12 h · nhs: up to 3× a day","use_duration":null,"take_with":"with or after food · swallowed whole with water (nhs)","pros":["longer gap between doses than most nsaids (8–12 h)","one sg pack is general sale list: aleve 220 mg (otc)","eases pain and reduces inflammation (healthhub)"],"cons":["prescription-only in sg above the 220 mg otc pack","stomach irritation and heartburn are common (healthhub)","nhs: max 3 days if bought without a prescription"],"dose_note":"sg aleve 220 mg otc label (sin12440p): '1 tablet every 8 to 12 hours while symptoms persist … Do not exceed 3 tablets in 24 hours unless directed to do so by a doctor'; 65 and over: 'Maximum of 2 tablets per day'; under 12: do not use; 'ALEVE should not be taken for more than 10 consecutive days'; nhs: 'Do not take naproxen for longer than 3 days if you bought it without a prescription' — as directed on the label or by your pharmacist. these figures are the OTC 220 mg pack only and do not apply to the prescription-only 250–500 mg strengths","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["a history of stomach or bowel ulcers or bleeding, or bleeding problems — healthhub: inform your healthcare professional","asthma, or a history of kidney, liver, heart problems or stroke — healthhub: inform your healthcare professional","pregnant or trying to get pregnant — nhs: may not be suitable","excessive alcohol — healthhub: increases the risk of bleeding"],"clashes":[{"src":["healthhub_naproxen"],"note":"healthhub: avoid taking together with other nsaids","with":"other nsaids (ibuprofen, diclofenac)"},{"src":["healthhub_naproxen","nhs_naproxen_int"],"note":"healthhub flags blood-thinning medications; nhs lists 'anticoagulants, such as warfarin'","with":"blood-thinning medicines (clopidogrel, warfarin)"},{"src":["nhs_naproxen_int"],"note":"nhs lists these among medicines that do not mix well with naproxen","with":"steroid medicines and antidepressants"},{"src":["nhs_naproxen_int"],"note":"nhs lists these among medicines that do not mix well with naproxen","with":"medicines for heart problems and high blood pressure"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, Health Sciences Authority), Forensicclassification column; all 5,511 rows pulled via the datastore_search API on 27 Aug 2026","quote":"SYNFLEX 275 mg | SIN05621P | Prescription Only; APO-NAPROXEN, SOPROXEN, SUNPROX | Prescription Only; ALEVE TABLET 220 mg | SIN12440P | General Sale List — 12 of 13 naproxen rows Prescription Only, none Pharmacy Only; no NAPROSYN row.","accessed":"2026-08-27"},{"id":"ndf_aleve","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12440p/","label":"MOH National Drug Formulary (Singapore) — ALEVE TABLET 220 mg (OTC Pack) [SIN12440P], naproxen sodium, Bayer (South East Asia) Pte Ltd","quote":"GENERAL SALE LIST … 1 tablet every 8 to 12 hours … Do not exceed 3 tablets in 24 hours … Maximum of 2 tablets per day … ALEVE should not be taken for more than 10 consecutive days","accessed":"2026-08-27"},{"id":"healthhub_naproxen","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/naproxen-oral","label":"HealthHub (MOH Singapore) — Naproxen Oral, article last reviewed 07 July 2026","quote":"non-steroidal anti-inflammatory drug (NSAID) … used to treat pain and reduce inflammation … best taken with meals … Avoid taking together with other NSAIDs (e.g. Ibuprofen, Diclofenac) … excessive … alcohol … increase the risk of bleeding","accessed":"2026-08-27"},{"id":"healthhub_naproxen_pre","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/naproxen-oral","label":"HealthHub (MOH Singapore) — Naproxen Oral, precautions and side effects sections","quote":"You have a history of stomach or bowel ulcers or bleeding, or bleeding problems … You have asthma … You have a history of kidney, liver, heart problems or stroke … Stomach discomfort/irritation e.g. stomach pain, heartburn","accessed":"2026-08-27"},{"id":"nhs_naproxen","url":"https://www.nhs.uk/medicines/naproxen/","label":"NHS medicines A–Z — Naproxen (what it is for, and who it may not suit)","quote":"relieve pain and reduce swelling (inflammation) … period pain, joint and muscle pain … a stomach ulcer … a heart, liver or kidney condition … asthma or allergies … pregnant or trying to get pregnant","accessed":"2026-08-27"},{"id":"nhs_naproxen_how","url":"https://www.nhs.uk/medicines/naproxen/","label":"NHS medicines A–Z — Naproxen (how and when to take it)","quote":"It's usually taken up to 3 times a day … swallow tablets whole with water … taken with or after food … Do not take naproxen for longer than 3 days if you bought it without a prescription","accessed":"2026-08-27"},{"id":"nhs_naproxen_int","url":"https://www.nhs.uk/medicines/naproxen/","label":"NHS medicines A–Z — Naproxen (medicines that do not mix well with it)","quote":"anticoagulants, such as warfarin … steroid medicines … antidepressants … medicines to treat heart problems and high blood pressure","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:26.600885+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}