Morphine
Medication
opioid analgesic
pain & fever
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Severe pain · SG labels say severe or chronic severe pain
When to take
HealthHub: the effect may reduce with time
Take with
HealthHub: with or after food · alcohol is to be avoided
Pros & cons
Pros
- HealthHub: used for severe pain, in several forms
- Ndf: mst continus gives prolonged relief, 12-hourly
- Seven morphine products are registered in Singapore
Cons
- Constipation, nausea and vomiting are common
- HealthHub: has the potential to cause addiction
- Breathing can be depressed — urgent care if affected
Sources
- HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; read from the cached copy at /tmp/hsa_all.json and filtered locally, not re-fetched · read 2026-08-27
what it says
“MST CONTINUS TABLET 10 mg SIN05506P and 30 mg SIN05508P; Morphine-hameln 10 mg/ml Injection SIN13598P; ORAMORPH SYRUP 2MG/ML SIN16036P; DBL MORPHINE SULFATE INJECTION SIN00757P; MORPHINE SULFATE KALCEKS SIN16891P; MORPHUS SIN17362P — all 7 read Prescription Only”
- MOH National Drug Formulary (Singapore) — MST CONTINUS TABLET 10 MG [SIN05506P], product information · read 2026-08-27
what it says
“MORPHINE BASE 7.5 MG EQV MORPHINE SULPHATE - 10 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code N02AA01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA”
- MOH National Drug Formulary (Singapore) — MST CONTINUS [SIN05506P], Therapeutic indications · read 2026-08-27
what it says
“Prolonged relief of severe pain”
- MOH National Drug Formulary (Singapore) — MST CONTINUS [SIN05506P], Posology and method of administration · read 2026-08-27
what it says
“The dosage is dependent upon the severity of the pain, the patient's age and previous history of analgesic requirements … Higher doses should be made, where possible in 25–50% increments as required.”
- MOH National Drug Formulary (Singapore) — MST CONTINUS [SIN05506P], Contraindications · read 2026-08-27
what it says
“Severe respiratory depression with hypoxia and/or hypercapnia, severe bronchial asthma, head injury, paralytic ileus … severe chronic obstructive pulmonary disease … concurrent administration of monoamine oxidase inhibitors or within two weeks of discontinuation of their use.”
- MOH National Drug Formulary (Singapore) — ORAMORPH SYRUP 2MG/ML [SIN16036P], section 4.1 Therapeutic indications · read 2026-08-27
what it says
“Oramorph is indicated for the symptomatic relief of severe chronic pain.”
- MOH National Drug Formulary (Singapore) — ORAMORPH SYRUP 2MG/ML [SIN16036P], section 4.2 Posology and method of administration · read 2026-08-27
what it says
“Under medical control the dose can be increased depending on the severity of pain … Adults: initial dose usually 10–30 mg morphine sulfate pentahydrate (corresponding to 5–15 ml Oramorph 2 mg/ml - syrup) every 4–6 hours.”
- MOH National Drug Formulary (Singapore) — ORAMORPH SYRUP 2MG/ML [SIN16036P], section 4.3 Contraindications · read 2026-08-27
what it says
“Acute respiratory insufficiency or respiratory depression, obstructive airways disease. Concurrent administration with monoamine oxidase (MAO) inhibitors or within 2 weeks of Discontinuation of treatment with MAO”
- HealthHub (MOH Singapore) — Morphine, medication information leaflet, uses (article last reviewed 30 April 2022) · read 2026-08-27
what it says
“This medication is used to treat severe pain. It belongs to a class of drugs known as opioids. There are a number of different morphine preparations which can be taken by mouth … Morphine slow release tablets.”
- HealthHub (MOH Singapore) — Morphine, administration · read 2026-08-27
what it says
“Take this medication with or after food. The effect of this medication may reduce with time … Slow release tablets should be swallowed whole and taken at the same time each day.”
- HealthHub (MOH Singapore) — Morphine, precautions · read 2026-08-27
what it says
“You have a history of fits. This drug may increase the risk of having a fit. You have a history of constipation or obstructive bowel disease … lung disease including asthma or chronic obstructive pulmonary disease (COPD).”
- HealthHub (MOH Singapore) — Morphine, common side effects · read 2026-08-27
what it says
“Morphine may cause constipation, nausea and vomiting … may cause drowsiness or dizziness which may impair physical or mental abilities … This medication has the potential to cause addiction.”
- HealthHub (MOH Singapore) — Morphine, rare but serious side effects · read 2026-08-27
what it says
“This medication may depress your breathing. Seek immediate medical attention should you experience breathing difficulty or problems. This medication may cause a drop in blood pressure.”
- HealthHub (MOH Singapore) — Morphine, food and medication to avoid · read 2026-08-27
what it says
“Morphine can generally be taken with most other foods or medications … Avoid alcohol. Alcohol may increase the risk of side effects with this medication.”
- HealthHub (MOH Singapore) — Morphine, precautions: cross-allergy to other opioids · read 2026-08-27
what it says
“You are allergic to this medication … This includes a history of allergy to other related drugs including other opioid drugs such as oxycodone, fentanyl and codeine.”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.