{"ok":true,"entry":{"slug":"morphine","kind":"medication","name":"morphine","aliases":["MST Continus","Oramorph"],"brands_sg":["MST Continus","Morphine-hameln","Oramorph","DBL Morphine Sulfate","Morphine Sulfate Kalceks"],"class":"opioid analgesic","tags":["pain-fever"],"use_for":"severe pain · sg labels say severe or chronic severe pain","use_after":"healthhub: the effect may reduce with time","use_duration":null,"take_with":"healthhub: with or after food · alcohol is to be avoided","pros":["healthhub: used for severe pain, in several forms","ndf: mst continus gives prolonged relief, 12-hourly","seven morphine products are registered in singapore"],"cons":["constipation, nausea and vomiting are common","healthhub: has the potential to cause addiction","breathing can be depressed — urgent care if affected"],"dose_note":"neither sg oral label states a maximum daily dose — both titrate. mst continus says \"The dosage is dependent upon the severity of the pain, the patient's age and previous history of analgesic requirements\" and that higher doses \"should be made, where possible in 25–50% increments\"; oramorph gives an adult \"initial dose usually 10–30 mg morphine sulfate pentahydrate … every 4–6 hours\" and adds that \"under medical control the dose can be increased\" — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["a history of fits — healthhub notes morphine may raise the risk of having a fit","a history of constipation or obstructive bowel disease — healthhub precaution","lung disease including asthma or copd — healthhub precaution; ndf contraindicates severe respiratory depression","allergy to other opioids such as oxycodone, fentanyl or codeine — healthhub precaution"],"clashes":[{"src":["hh_morphine_food"],"food":true,"note":"healthhub: may increase the risk of side effects with this medication","with":"alcohol"},{"src":["ndf_mst_ci","ndf_oramorph_ci"],"note":"ndf: contraindicated concurrently or within 2 weeks of stopping them, on both the mst continus and oramorph labels","with":"monoamine oxidase (mao) inhibitors"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; read from the cached copy at /tmp/hsa_all.json and filtered locally, not re-fetched","quote":"MST CONTINUS TABLET 10 mg SIN05506P and 30 mg SIN05508P; Morphine-hameln 10 mg/ml Injection SIN13598P; ORAMORPH SYRUP 2MG/ML SIN16036P; DBL MORPHINE SULFATE INJECTION SIN00757P; MORPHINE SULFATE KALCEKS SIN16891P; MORPHUS SIN17362P — all 7 read Prescription Only","accessed":"2026-08-27"},{"id":"ndf_mst","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin05506p/","label":"MOH National Drug Formulary (Singapore) — MST CONTINUS TABLET 10 MG [SIN05506P], product information","quote":"MORPHINE BASE 7.5 MG EQV MORPHINE SULPHATE - 10 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code N02AA01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA","accessed":"2026-08-27"},{"id":"ndf_mst_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin05506p/","label":"MOH National Drug Formulary (Singapore) — MST CONTINUS [SIN05506P], Therapeutic indications","quote":"Prolonged relief of severe pain","accessed":"2026-08-27"},{"id":"ndf_mst_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin05506p/","label":"MOH National Drug Formulary (Singapore) — MST CONTINUS [SIN05506P], Posology and method of administration","quote":"The dosage is dependent upon the severity of the pain, the patient's age and previous history of analgesic requirements … Higher doses should be made, where possible in 25–50% increments as required.","accessed":"2026-08-27"},{"id":"ndf_mst_ci","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin05506p/","label":"MOH National Drug Formulary (Singapore) — MST CONTINUS [SIN05506P], Contraindications","quote":"Severe respiratory depression with hypoxia and/or hypercapnia, severe bronchial asthma, head injury, paralytic ileus … severe chronic obstructive pulmonary disease … concurrent administration of monoamine oxidase inhibitors or within two weeks of discontinuation of their use.","accessed":"2026-08-27"},{"id":"ndf_oramorph_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16036p/","label":"MOH National Drug Formulary (Singapore) — ORAMORPH SYRUP 2MG/ML [SIN16036P], section 4.1 Therapeutic indications","quote":"Oramorph is indicated for the symptomatic relief of severe chronic pain.","accessed":"2026-08-27"},{"id":"ndf_oramorph_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16036p/","label":"MOH National Drug Formulary (Singapore) — ORAMORPH SYRUP 2MG/ML [SIN16036P], section 4.2 Posology and method of administration","quote":"Under medical control the dose can be increased depending on the severity of pain … Adults: initial dose usually 10–30 mg morphine sulfate pentahydrate (corresponding to 5–15 ml Oramorph 2 mg/ml - syrup) every 4–6 hours.","accessed":"2026-08-27"},{"id":"ndf_oramorph_ci","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin16036p/","label":"MOH National Drug Formulary (Singapore) — ORAMORPH SYRUP 2MG/ML [SIN16036P], section 4.3 Contraindications","quote":"Acute respiratory insufficiency or respiratory depression, obstructive airways disease. Concurrent administration with monoamine oxidase (MAO) inhibitors or within 2 weeks of Discontinuation of treatment with MAO","accessed":"2026-08-27"},{"id":"hh_morphine","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, medication information leaflet, uses (article last reviewed 30 April 2022)","quote":"This medication is used to treat severe pain. It belongs to a class of drugs known as opioids. There are a number of different morphine preparations which can be taken by mouth … Morphine slow release tablets.","accessed":"2026-08-27"},{"id":"hh_morphine_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, administration","quote":"Take this medication with or after food. The effect of this medication may reduce with time … Slow release tablets should be swallowed whole and taken at the same time each day.","accessed":"2026-08-27"},{"id":"hh_morphine_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, precautions","quote":"You have a history of fits. This drug may increase the risk of having a fit. You have a history of constipation or obstructive bowel disease … lung disease including asthma or chronic obstructive pulmonary disease (COPD).","accessed":"2026-08-27"},{"id":"hh_morphine_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, common side effects","quote":"Morphine may cause constipation, nausea and vomiting … may cause drowsiness or dizziness which may impair physical or mental abilities … This medication has the potential to cause addiction.","accessed":"2026-08-27"},{"id":"hh_morphine_rare","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, rare but serious side effects","quote":"This medication may depress your breathing. Seek immediate medical attention should you experience breathing difficulty or problems. This medication may cause a drop in blood pressure.","accessed":"2026-08-27"},{"id":"hh_morphine_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, food and medication to avoid","quote":"Morphine can generally be taken with most other foods or medications … Avoid alcohol. Alcohol may increase the risk of side effects with this medication.","accessed":"2026-08-27"},{"id":"hh_morphine_prec2","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/morphine","label":"HealthHub (MOH Singapore) — Morphine, precautions: cross-allergy to other opioids","quote":"You are allergic to this medication … This includes a history of allergy to other related drugs including other opioid drugs such as oxycodone, fentanyl and codeine.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:26.600885+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}