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Metoprolol

Medication beta blocker heart & blood pressure
Aka: metoprolol tartrate, metoprolol succinate
Brands seen in Singapore: Apo-Metoprolol, Denex
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for blood pressure, angina, migraine and more
When to take
HealthHub: with or after food, and not stopped suddenly
Take with
Food or straight after a meal (HealthHub, FDA label)
Pros & cons
Pros
  • HealthHub: covers bp, angina and irregular heartbeat
  • HealthHub: also used to prevent migraine
  • FDA label: once daily with food or after a meal
Cons
  • HealthHub: dizziness, cold fingers or toes, tiredness
  • HealthHub: may mask low blood sugar signs in diabetes
  • HealthHub: stopping suddenly may worsen the condition
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, filtered locally for metoprolol) · read 2026-08-27
    what it says
    “All 3 registered metoprolol products carry Forensicclassification 'Prescription Only' and all are METOPROLOL TARTRATE — SIN00440P APO-METOPROLOL TABLET 100 mg; SIN00445P APO-METOPROLOL TABLET 50 mg; SIN01331P DENEX TABLET 100 mg”
  2. NHS Medicines A-Z — Metoprolol (index page) · read 2026-08-27
    what it says
    “Metoprolol: medicine to treat high blood pressure (hypertension) ... Find out how metoprolol treats high blood pressure and heart problems, prevents migraine, and how to take it.”
  3. NHS Medicines A-Z — Metoprolol: cautions with other medicines · read 2026-08-27
    what it says
    “non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen - they can stop metoprolol working properly; medicines for diabetes - metoprolol may make it more difficult to recognise the warning signs of low blood sugar”
  4. NHS Medicines A-Z — Metoprolol: other medicines that lower blood pressure · read 2026-08-27
    what it says
    “other medicines for high blood pressure (hypertension) - when taken together with metoprolol, this can lower your blood pressure too much ... medicines for allergies, such as ephedrine, noradrenaline or adrenaline”
  5. NHS Medicines A-Z — Metoprolol: mixing it with herbal remedies and supplements · read 2026-08-27
    what it says
    “There might be a problem taking some herbal remedies and supplements together with metoprolol, especially ones that cause side effects like low blood pressure.”
  6. HealthHub (Pharmaceutical Society of Singapore) — Metoprolol: what is this medication for · read 2026-08-27
    what it says
    “Metoprolol belongs to a group of medications known as beta-blockers ... High blood pressure; Irregular heartbeat; Reduce chest pain/ discomfort (Angina); Heart attack ... hyperthyroidism ... Migraine, a type of headache”
  7. HealthHub — Metoprolol: how should I take or use this medication · read 2026-08-27
    what it says
    “You should take this medication with or after food ... do not stop this medication suddenly without consulting your healthcare professional. Stopping your medication suddenly may worsen your condition.”
  8. HealthHub — Metoprolol: common side effects · read 2026-08-27
    what it says
    “Dizziness and lightheadedness ... Coldness, numbness or tingling sensation of your fingers or toes; Feeling weak and tired, and that your heart beats slower; Shortness of breath; Problems with sexual intercourse”
  9. HealthHub — Metoprolol: what precautions should I take · read 2026-08-27
    what it says
    “You have asthma or other breathing problems - this medication may worsen or cause an asthma attack. You have pre-diabetes or diabetes - this medication may hide symptoms of low blood sugar such as fast heartbeat or tremors.”
  10. NHS Medicines A-Z — Metoprolol: common questions (alcohol) · read 2026-08-29
    what it says
    “You can drink alcohol while taking metoprolol but be careful as drinking alcohol can increase the effects of metoprolol so that it lowers your blood pressure too much. This can make you feel dizzy or light-headed.”
  11. US FDA label for LOPRESSOR (metoprolol tartrate), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2023-09-14) · read 2026-08-27
    what it says
    “Administer once daily with food or after a meal ... The effective dosage range of Lopressor tablets is 100 mg to 450 mg per day. Dosages above 450 mg per day have not been studied.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.