{"ok":true,"entry":{"slug":"metoprolol","kind":"medication","name":"metoprolol","aliases":["metoprolol tartrate","metoprolol succinate"],"brands_sg":["Apo-Metoprolol","Denex"],"class":"beta blocker","tags":["heart-bp"],"use_for":"prescribed for blood pressure, angina, migraine and more","use_after":"healthhub: with or after food, and not stopped suddenly","use_duration":null,"take_with":"food or straight after a meal (healthhub, fda label)","pros":["healthhub: covers bp, angina and irregular heartbeat","healthhub: also used to prevent migraine","fda label: once daily with food or after a meal"],"cons":["healthhub: dizziness, cold fingers or toes, tiredness","healthhub: may mask low blood sugar signs in diabetes","healthhub: stopping suddenly may worsen the condition"],"dose_note":"the us fda label for lopressor (metoprolol tartrate) states 'The effective dosage range of Lopressor tablets is 100 mg to 450 mg per day' for hypertension and adds 'Dosages above 450 mg per day have not been studied'; for angina the same label gives '100 to 400 mg per day'. sg-registered metoprolol tartrate tablets are 50 mg and 100 mg. in singapore the prescriber sets the dose, as directed on the label or by your pharmacist or doctor.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["asthma or other breathing problems — healthhub: may worsen or cause an attack","diabetes or pre-diabetes — healthhub: low-sugar warning signs may be hidden","pregnant, planning a pregnancy or breastfeeding (healthhub)","weeks or more on it — healthhub: not stopped suddenly without advice"],"clashes":[{"src":["nhs_meto_mix2"],"note":"nhs: together they can lower your blood pressure too much","with":"other blood-pressure medicines"},{"src":["nhs_meto_mix"],"note":"nhs: they can stop metoprolol working properly","with":"nsaids such as ibuprofen"},{"src":["nhs_meto_mix","hh_meto_prec"],"note":"nhs: metoprolol may make it harder to recognise the warning signs of low blood sugar","with":"diabetes medicines"},{"src":["nhs_meto_mix2"],"note":"nhs lists these among medicines that may affect how metoprolol works","with":"allergy medicines such as ephedrine, noradrenaline or adrenaline"},{"src":["nhs_meto_herbal"],"note":"nhs: there might be a problem taking some of these together with metoprolol","with":"herbal remedies and supplements that lower blood pressure"},{"src":["nhs_meto_alcohol"],"food":true,"note":"nhs: can increase the effects of metoprolol and lower your blood pressure too much","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, filtered locally for metoprolol)","quote":"All 3 registered metoprolol products carry Forensicclassification 'Prescription Only' and all are METOPROLOL TARTRATE — SIN00440P APO-METOPROLOL TABLET 100 mg; SIN00445P APO-METOPROLOL TABLET 50 mg; SIN01331P DENEX TABLET 100 mg","accessed":"2026-08-27"},{"id":"nhs_meto_hub","url":"https://www.nhs.uk/medicines/metoprolol/","label":"NHS Medicines A-Z — Metoprolol (index page)","quote":"Metoprolol: medicine to treat high blood pressure (hypertension) ... Find out how metoprolol treats high blood pressure and heart problems, prevents migraine, and how to take it.","accessed":"2026-08-27"},{"id":"nhs_meto_mix","url":"https://www.nhs.uk/medicines/metoprolol/taking-metoprolol-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Metoprolol: cautions with other medicines","quote":"non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen - they can stop metoprolol working properly; medicines for diabetes - metoprolol may make it more difficult to recognise the warning signs of low blood sugar","accessed":"2026-08-27"},{"id":"nhs_meto_mix2","url":"https://www.nhs.uk/medicines/metoprolol/taking-metoprolol-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Metoprolol: other medicines that lower blood pressure","quote":"other medicines for high blood pressure (hypertension) - when taken together with metoprolol, this can lower your blood pressure too much ... medicines for allergies, such as ephedrine, noradrenaline or adrenaline","accessed":"2026-08-27"},{"id":"nhs_meto_herbal","url":"https://www.nhs.uk/medicines/metoprolol/taking-metoprolol-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Metoprolol: mixing it with herbal remedies and supplements","quote":"There might be a problem taking some herbal remedies and supplements together with metoprolol, especially ones that cause side effects like low blood pressure.","accessed":"2026-08-27"},{"id":"hh_meto_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoprolol","label":"HealthHub (Pharmaceutical Society of Singapore) — Metoprolol: what is this medication for","quote":"Metoprolol belongs to a group of medications known as beta-blockers ... High blood pressure; Irregular heartbeat; Reduce chest pain/ discomfort (Angina); Heart attack ... hyperthyroidism ... Migraine, a type of headache","accessed":"2026-08-27"},{"id":"hh_meto_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoprolol","label":"HealthHub — Metoprolol: how should I take or use this medication","quote":"You should take this medication with or after food ... do not stop this medication suddenly without consulting your healthcare professional. Stopping your medication suddenly may worsen your condition.","accessed":"2026-08-27"},{"id":"hh_meto_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoprolol","label":"HealthHub — Metoprolol: common side effects","quote":"Dizziness and lightheadedness ... Coldness, numbness or tingling sensation of your fingers or toes; Feeling weak and tired, and that your heart beats slower; Shortness of breath; Problems with sexual intercourse","accessed":"2026-08-27"},{"id":"hh_meto_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoprolol","label":"HealthHub — Metoprolol: what precautions should I take","quote":"You have asthma or other breathing problems - this medication may worsen or cause an asthma attack. You have pre-diabetes or diabetes - this medication may hide symptoms of low blood sugar such as fast heartbeat or tremors.","accessed":"2026-08-27"},{"id":"nhs_meto_alcohol","url":"https://www.nhs.uk/medicines/metoprolol/common-questions-about-metoprolol/","label":"NHS Medicines A-Z — Metoprolol: common questions (alcohol)","quote":"You can drink alcohol while taking metoprolol but be careful as drinking alcohol can increase the effects of metoprolol so that it lowers your blood pressure too much. This can make you feel dizzy or light-headed.","accessed":"2026-08-29"},{"id":"fda_lopressor_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22LOPRESSOR%22&limit=1","label":"US FDA label for LOPRESSOR (metoprolol tartrate), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2023-09-14)","quote":"Administer once daily with food or after a meal ... The effective dosage range of Lopressor tablets is 100 mg to 450 mg per day. Dosages above 450 mg per day have not been studied.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:26.600885+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}