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Metoclopramide

Medication prokinetic antiemetic digestive
Aka: Maxolon
Brands seen in Singapore: Pulin
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for nausea and vomiting
When to take
HealthHub: 30 minutes before food, 6 hours apart
Take with
Water · NHS: up to 3 times a day, usually short term
Pros & cons
Pros
  • NHS: offered to prevent sickness after chemotherapy
  • HealthHub: also speeds up stomach and gut movement
  • NHS: suitable for most adults and children over 1
Cons
  • NHS: drowsiness, low mood, diarrhoea, weakness
  • NHS: tics, tremors, muscle stiffness and spasms
  • HealthHub: rare tardive dyskinesia with long use
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered locally) · read 2026-08-27
    what it says
    “All 5 registered metoclopramide products carry Forensicclassification 'Prescription Only' — SIN02804P METOCLOPRAMIDE TABLET 10 mg · SIN03349P METOCLOPRAMIDE SYRUP 5 mg/5 ml · SIN10581P PULIN FILM-COATED TABLET 10 mg · SIN06638P and SIN05202P injections. No Maxolon row exists.”
  2. NHS Medicines A-Z — Metoclopramide: what metoclopramide is for · read 2026-08-27
    what it says
    “Metoclopramide is a medicine used to stop you feeling sick (nausea) and being sick (vomiting). It's only available on prescription. … You may be offered it to prevent any sickness from happening after you've had chemotherapy or radiotherapy.”
  3. NHS Medicines A-Z — Metoclopramide: how to take metoclopramide · read 2026-08-27
    what it says
    “Metoclopramide can be taken up to 3 times a day. You need to leave at least 6 hours between each dose … it can cause side effects if taken for longer than 5 days.”
  4. NHS Medicines A-Z — Metoclopramide: side effects · read 2026-08-27
    what it says
    “Common side effects of metoclopramide can include: feeling sleepy (drowsy); low mood or depression; diarrhoea; feeling unusually weak … The most common serious side effect is that you get uncontrollable physical movements, such as tics, tremors, muscle stiffness and spasms.”
  5. NHS Medicines A-Z — Metoclopramide: who can and cannot take it, breastfeeding · read 2026-08-27
    what it says
    “Metoclopramide is suitable for most adults and children aged 1 year or over … it may not be suitable if: you have epilepsy; you have Parkinson's disease; you have a blockage … inside your stomach, intestines or bowel”
  6. NHS Medicines A-Z — Metoclopramide: taking it with other medicines · read 2026-08-27
    what it says
    “This includes some types of: SSRI antidepressants; medicines used for Parkinson's disease; medicines that can make you feel sleepy (drowsy), such as medicines for anxiety, or strong painkillers; medicines for psychosis”
  7. NHS Medicines A-Z — Metoclopramide: food, drink and alcohol · read 2026-08-27
    what it says
    “You can eat and drink as normal when taking metoclopramide. But it's best not to drink alcohol because this increases the risk of side effects.”
  8. HealthHub (Pharmaceutical Society of Singapore) — Metoclopramide: what is this medication for · read 2026-08-27
    what it says
    “Metoclopramide works by blocking a chemical in the brain that causes nausea and vomiting. It also increases the movement of the stomach and intestines.”
  9. HealthHub — Metoclopramide: how should I take or use this medication · read 2026-08-27
    what it says
    “Take this medication 30 minutes before food. Take each dose at least 6 hours apart. Do not exceed 30mg in any 24-hour period unless recommended by a healthcare professional.”
  10. HealthHub — Metoclopramide: what precautions should I take · read 2026-08-27
    what it says
    “You have a history of Gastrointestinal obstruction or bleed; Kidney disease; Liver disease; Parkinson's disease (a condition that affects your body movement); Uncontrolled blood pressure”
  11. HealthHub — Metoclopramide: rare but serious side effects · read 2026-08-27
    what it says
    “Very rarely, Metoclopramide can lead to tardive dyskinesia, where there are uncontrollable movements (such as in the face, tongue, jaw or other parts of the body). Do not use Metoclopramide for a long period of time”
  12. HealthHub — Metoclopramide: what food or medication should I avoid · read 2026-08-27
    what it says
    “Risperidone, Quetiapine, Haloperidol or Aripiprazole … Trimetazidine … Rivastigmine … Using these medications together with Metoclopramide can increase your risk of developing tardive dyskinesia. Inform your doctor if you are on medications for Parkinson's disease”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.