{"ok":true,"entry":{"slug":"metoclopramide","kind":"medication","name":"metoclopramide","aliases":["Maxolon"],"brands_sg":["Pulin"],"class":"prokinetic antiemetic","tags":["digestive"],"use_for":"prescribed for nausea and vomiting","use_after":"healthhub: 30 minutes before food, 6 hours apart","use_duration":null,"take_with":"water · nhs: up to 3 times a day, usually short term","pros":["nhs: offered to prevent sickness after chemotherapy","healthhub: also speeds up stomach and gut movement","nhs: suitable for most adults and children over 1"],"cons":["nhs: drowsiness, low mood, diarrhoea, weakness","nhs: tics, tremors, muscle stiffness and spasms","healthhub: rare tardive dyskinesia with long use"],"dose_note":"healthhub (pharmaceutical society of singapore) states 'Do not exceed 30mg in any 24-hour period unless recommended by a healthcare professional' and 'Take each dose at least 6 hours apart' — 30 mg in 24 hours is the sg-facing ceiling. nhs adds that it 'can be taken up to 3 times a day' and is usually prescribed for a short time 'as it can cause side effects if taken for longer than 5 days'. sg-registered oral strengths are 10 mg tablets and 5 mg/5 ml syrup. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["epilepsy or parkinson's disease (nhs)","a blockage, hole, tear or bleed in the gut, or recent gut surgery (nhs)","kidney disease, liver disease or uncontrolled blood pressure (healthhub)","breastfeeding — nhs: not usually used while breastfeeding"],"clashes":[{"src":["hh_meto_interactions","nhs_meto_mix"],"note":"healthhub: using these with metoclopramide can increase the risk of tardive dyskinesia","with":"risperidone, quetiapine, haloperidol, aripiprazole"},{"src":["hh_meto_interactions"],"note":"healthhub lists both among medicines that raise the risk of tardive dyskinesia","with":"trimetazidine or rivastigmine"},{"src":["hh_meto_interactions","nhs_meto_mix"],"note":"healthhub: metoclopramide may make these medications less effective","with":"parkinson's disease medicines"},{"src":["nhs_meto_mix"],"note":"nhs lists ssri antidepressants among medicines that may not mix well","with":"ssri antidepressants"},{"src":["nhs_meto_mix","nhs_meto_food"],"food":true,"note":"nhs: strong painkillers and anxiety medicines may not mix well; alcohol raises the risk of side effects","with":"alcohol and sedating medicines"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered locally)","quote":"All 5 registered metoclopramide products carry Forensicclassification 'Prescription Only' — SIN02804P METOCLOPRAMIDE TABLET 10 mg · SIN03349P METOCLOPRAMIDE SYRUP 5 mg/5 ml · SIN10581P PULIN FILM-COATED TABLET 10 mg · SIN06638P and SIN05202P injections. No Maxolon row exists.","accessed":"2026-08-27"},{"id":"nhs_meto_about","url":"https://www.nhs.uk/medicines/metoclopramide/","label":"NHS Medicines A-Z — Metoclopramide: what metoclopramide is for","quote":"Metoclopramide is a medicine used to stop you feeling sick (nausea) and being sick (vomiting). It's only available on prescription. … You may be offered it to prevent any sickness from happening after you've had chemotherapy or radiotherapy.","accessed":"2026-08-27"},{"id":"nhs_meto_howto","url":"https://www.nhs.uk/medicines/metoclopramide/","label":"NHS Medicines A-Z — Metoclopramide: how to take metoclopramide","quote":"Metoclopramide can be taken up to 3 times a day. You need to leave at least 6 hours between each dose … it can cause side effects if taken for longer than 5 days.","accessed":"2026-08-27"},{"id":"nhs_meto_side","url":"https://www.nhs.uk/medicines/metoclopramide/","label":"NHS Medicines A-Z — Metoclopramide: side effects","quote":"Common side effects of metoclopramide can include: feeling sleepy (drowsy); low mood or depression; diarrhoea; feeling unusually weak … The most common serious side effect is that you get uncontrollable physical movements, such as tics, tremors, muscle stiffness and spasms.","accessed":"2026-08-27"},{"id":"nhs_meto_who","url":"https://www.nhs.uk/medicines/metoclopramide/","label":"NHS Medicines A-Z — Metoclopramide: who can and cannot take it, breastfeeding","quote":"Metoclopramide is suitable for most adults and children aged 1 year or over … it may not be suitable if: you have epilepsy; you have Parkinson's disease; you have a blockage … inside your stomach, intestines or bowel","accessed":"2026-08-27"},{"id":"nhs_meto_mix","url":"https://www.nhs.uk/medicines/metoclopramide/","label":"NHS Medicines A-Z — Metoclopramide: taking it with other medicines","quote":"This includes some types of: SSRI antidepressants; medicines used for Parkinson's disease; medicines that can make you feel sleepy (drowsy), such as medicines for anxiety, or strong painkillers; medicines for psychosis","accessed":"2026-08-27"},{"id":"nhs_meto_food","url":"https://www.nhs.uk/medicines/metoclopramide/","label":"NHS Medicines A-Z — Metoclopramide: food, drink and alcohol","quote":"You can eat and drink as normal when taking metoclopramide. But it's best not to drink alcohol because this increases the risk of side effects.","accessed":"2026-08-27"},{"id":"hh_meto_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoclopramide","label":"HealthHub (Pharmaceutical Society of Singapore) — Metoclopramide: what is this medication for","quote":"Metoclopramide works by blocking a chemical in the brain that causes nausea and vomiting. It also increases the movement of the stomach and intestines.","accessed":"2026-08-27"},{"id":"hh_meto_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoclopramide","label":"HealthHub — Metoclopramide: how should I take or use this medication","quote":"Take this medication 30 minutes before food. Take each dose at least 6 hours apart. Do not exceed 30mg in any 24-hour period unless recommended by a healthcare professional.","accessed":"2026-08-27"},{"id":"hh_meto_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoclopramide","label":"HealthHub — Metoclopramide: what precautions should I take","quote":"You have a history of Gastrointestinal obstruction or bleed; Kidney disease; Liver disease; Parkinson's disease (a condition that affects your body movement); Uncontrolled blood pressure","accessed":"2026-08-27"},{"id":"hh_meto_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoclopramide","label":"HealthHub — Metoclopramide: rare but serious side effects","quote":"Very rarely, Metoclopramide can lead to tardive dyskinesia, where there are uncontrollable movements (such as in the face, tongue, jaw or other parts of the body). Do not use Metoclopramide for a long period of time","accessed":"2026-08-27"},{"id":"hh_meto_interactions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/metoclopramide","label":"HealthHub — Metoclopramide: what food or medication should I avoid","quote":"Risperidone, Quetiapine, Haloperidol or Aripiprazole … Trimetazidine … Rivastigmine … Using these medications together with Metoclopramide can increase your risk of developing tardive dyskinesia. Inform your doctor if you are on medications for Parkinson's disease","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:26.600885+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}