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Methylprednisolone

Medication corticosteroid other
Aka: Medrol
Brands seen in Singapore: Solu-Medrol, Lyo-Drol
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for inflammation and immune or allergic flares
When to take
SG label: the lowest dose, for the shortest period
Pros & cons
Pros
  • FDA: oral medrol runs from 4 mg to 48 mg a day
  • SG label: iv or im, dosed to the condition not the age
  • FDA: alternate-day dosing can blunt steroid harms
Cons
  • FDA: infections come easier and signs can be masked
  • FDA: mood swings, insomnia, even psychosis reported
  • FDA: bone thinning, high sugar, cushingoid changes
Sources
  1. HSA — Listing of Registered Therapeutic Products (open dataset on data.gov.sg; same register as HSA Infosearch) · read 2026-08-27
    what it says
    “All 6 methylprednisolone products are 'Prescription Only' and all are injections: SIN04683P SOLU-MEDROL 500 mg/8 ml, SIN14594P METHYLPREDNISOLONE 500mg, and SIN17531P–SIN17534P LYO-DROL 40, 125, 500 and 1000 mg/vial (IV/IM).”
  2. MOH National Drug Formulary — SOLU-MEDROL FOR INJECTION 500 MG/8 ML [SIN04683P], SG product information (last updated 28 July 2026) · read 2026-08-27
    what it says
    “PRESCRIPTION ONLY MEDICINES … The lowest possible dose of corticosteroid should be used … for the minimum period … administer 30 mg/kg IV … repeated every 4 to 6 hours for up to 48 hours … pulses … 250 – 1000 mg/day.”
  3. FDA / openFDA drug label — MEDROL (methylprednisolone) tablets, Pharmacia & Upjohn prescribing information (effective 14 Nov 2025) · read 2026-08-27
    what it says
    “The initial dosage of MEDROL Tablets may vary from 4 mg to 48 mg of methylprednisolone per day … in selected patients higher initial doses may be required … Corticosteroids … suppress the immune system and increase the risk of infection.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.