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Meloxicam

Medication NSAID pain & fever
Aka: Mobic
Brands seen in Singapore: Mobic, Melox, Arrox
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for osteoarthritis and rheumatoid arthritis
When to take
FDA: once daily; timing of meals does not matter
Take with
Water · FDA: may be taken without regard to meals
Pros & cons
Pros
  • FDA: 7.5 mg once daily is the usual starting dose
  • FDA: taken without regard to the timing of meals
  • SG register: all three products are 7.5 mg tablets
Cons
  • FDA: boxed warning on heart attack and stroke risk
  • FDA: boxed warning on stomach bleeding and ulcers
  • NHS: indigestion, stomach ache, nausea, diarrhoea
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 3 registered meloxicam products read Forensicclassification 'Prescription Only' — SIN09554P MOBIC TABLET 7.5 mg · SIN12127P MELOX TABLET 7.5 mg · SIN14305P Arrox Tablet 7.5mg, ATC M01AC06.”
  2. US FDA label — meloxicam tablets USP, section 1 Indications and Usage, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Meloxicam tablet USP is a non-steroidal anti-inflammatory drug indicated for: Osteoarthritis (OA); Rheumatoid Arthritis (RA); Juvenile Rheumatoid Arthritis (JRA) in patients who weigh ≥60 kg”
  3. US FDA label — meloxicam tablets USP, section 2 Dosage and Administration, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Use the lowest effective dosage for the shortest duration … In adults, the maximum recommended daily oral dose of meloxicam tablets is 15 mg regardless of formulation. In patients with hemodialysis, a maximum daily dosage of 7.5 mg is recommended”
  4. US FDA label — meloxicam tablets USP, boxed warning, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke … NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines”
  5. US FDA label — meloxicam tablets USP, section 4 Contraindications, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Known hypersensitivity to meloxicam or any components of the drug product; History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs; In the setting of CABG surgery”
  6. US FDA label — meloxicam tablets USP, section 7 Drug Interactions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Meloxicam and anticoagulants such as warfarin have a synergistic effect on bleeding … Concomitant use of meloxicam and low dose aspirin or analgesic doses of aspirin is not generally recommended because of the increased risk of bleeding”
  7. NHS — NSAIDs: side effects (class page; NHS has no meloxicam page) · read 2026-08-27
    what it says
    “Some common side effects of NSAIDs include: indigestion and stomach ache; feeling and being sick; diarrhoea; feeling dizzy; a rash; headaches … stomach ulcers or bleeding inside your stomach … kidney problems”
  8. NHS — NSAIDs: who can take them, and mixing with other medicines · read 2026-08-27
    what it says
    “Most adults can take non-steroidal anti-inflammatory drugs (NSAIDs). They're not usually recommended if you're pregnant or breastfeeding … It can cause problems if you take NSAIDs with medicines such as: other NSAIDs; anticoagulants (such as warfarin); steroids; antidepressants”
  9. US FDA label — meloxicam tablets USP, sections 2.1–2.2 (starting dose, meals), via openFDA drug/label.json · read 2026-08-27
    what it says
    “the recommended starting and maintenance oral dose of meloxicam tablets is 7.5 mg once daily … Meloxicam tablets may be taken without regard to timing of meals.”
  10. US FDA label — meloxicam tablets USP, boxed warning (who is at greater GI risk), via openFDA drug/label.json · read 2026-08-27
    what it says
    “Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events”
  11. US FDA label — meloxicam tablets USP, section 7 Drug Interactions (serotonergic drugs), via openFDA drug/label.json · read 2026-08-27
    what it says
    “concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than an NSAID alone”
  12. US FDA label — meloxicam tablets USP, section 7 Drug Interactions (lithium, methotrexate), via openFDA drug/label.json · read 2026-08-27
    what it says
    “NSAIDs have produced elevations in plasma lithium levels and reductions in renal lithium clearance … Concomitant use of NSAIDs and methotrexate may increase the risk for methotrexate toxicity”
  13. US FDA label — meloxicam tablets USP, section 7 Drug Interactions (antihypertensives, diuretics), via openFDA drug/label.json · read 2026-08-27
    what it says
    “NSAIDs may diminish the antihypertensive effect of angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers … NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.