{"ok":true,"entry":{"slug":"meloxicam","kind":"medication","name":"meloxicam","aliases":["Mobic"],"brands_sg":["Mobic","Melox","Arrox"],"class":"NSAID","tags":["pain-fever"],"use_for":"prescribed for osteoarthritis and rheumatoid arthritis","use_after":"fda: once daily; timing of meals does not matter","use_duration":null,"take_with":"water · fda: may be taken without regard to meals","pros":["fda: 7.5 mg once daily is the usual starting dose","fda: taken without regard to the timing of meals","sg register: all three products are 7.5 mg tablets"],"cons":["fda: boxed warning on heart attack and stroke risk","fda: boxed warning on stomach bleeding and ulcers","nhs: indigestion, stomach ache, nausea, diarrhoea"],"dose_note":"the us fda label for meloxicam tablets states 'In adults, the maximum recommended daily oral dose of meloxicam tablets is 15 mg regardless of formulation', with 7.5 mg once daily as the starting and maintenance dose for osteoarthritis and rheumatoid arthritis, and adds 'In patients on hemodialysis, the maximum dosage of meloxicam is 7.5 mg' a day; the label also asks for 'the lowest effective dosage for the shortest duration'. every sg-registered meloxicam product is a 7.5 mg tablet. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["asthma or a past reaction to aspirin or nsaids (fda)","fda: contraindicated around bypass graft surgery","a past stomach ulcer or gi bleed, or older age (fda)","pregnancy or breastfeeding — nhs: not usually advised"],"clashes":[{"src":["fda_mel_di"],"note":"fda: a synergistic effect on bleeding, and an increased risk of serious bleeding","with":"warfarin and other anticoagulants"},{"src":["fda_mel_di"],"note":"fda: concomitant use is not generally recommended because of the increased risk of bleeding","with":"aspirin"},{"src":["fda_mel_di2"],"note":"fda: may potentiate the bleeding risk more than an nsaid alone","with":"ssri and snri antidepressants"},{"src":["fda_mel_di4"],"note":"fda: nsaids may blunt the blood-pressure effect and, with volume depletion, worsen kidney function","with":"ace inhibitors, arbs, beta blockers, diuretics"},{"src":["fda_mel_di3"],"note":"fda: nsaids raise lithium levels and may increase methotrexate toxicity","with":"lithium and methotrexate"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 3 registered meloxicam products read Forensicclassification 'Prescription Only' — SIN09554P MOBIC TABLET 7.5 mg · SIN12127P MELOX TABLET 7.5 mg · SIN14305P Arrox Tablet 7.5mg, ATC M01AC06.","accessed":"2026-08-27"},{"id":"fda_mel_ind","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 1 Indications and Usage, via openFDA drug/label.json","quote":"Meloxicam tablet USP is a non-steroidal anti-inflammatory drug indicated for: Osteoarthritis (OA); Rheumatoid Arthritis (RA); Juvenile Rheumatoid Arthritis (JRA) in patients who weigh ≥60 kg","accessed":"2026-08-27"},{"id":"fda_mel_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 2 Dosage and Administration, via openFDA drug/label.json","quote":"Use the lowest effective dosage for the shortest duration … In adults, the maximum recommended daily oral dose of meloxicam tablets is 15 mg regardless of formulation. In patients with hemodialysis, a maximum daily dosage of 7.5 mg is recommended","accessed":"2026-08-27"},{"id":"fda_mel_boxed","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, boxed warning, via openFDA drug/label.json","quote":"Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke … NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines","accessed":"2026-08-27"},{"id":"fda_mel_ci","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 4 Contraindications, via openFDA drug/label.json","quote":"Known hypersensitivity to meloxicam or any components of the drug product; History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs; In the setting of CABG surgery","accessed":"2026-08-27"},{"id":"fda_mel_di","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 7 Drug Interactions, via openFDA drug/label.json","quote":"Meloxicam and anticoagulants such as warfarin have a synergistic effect on bleeding … Concomitant use of meloxicam and low dose aspirin or analgesic doses of aspirin is not generally recommended because of the increased risk of bleeding","accessed":"2026-08-27"},{"id":"nhs_nsaids_side","url":"https://www.nhs.uk/conditions/nsaids/","label":"NHS — NSAIDs: side effects (class page; NHS has no meloxicam page)","quote":"Some common side effects of NSAIDs include: indigestion and stomach ache; feeling and being sick; diarrhoea; feeling dizzy; a rash; headaches … stomach ulcers or bleeding inside your stomach … kidney problems","accessed":"2026-08-27"},{"id":"nhs_nsaids_who","url":"https://www.nhs.uk/conditions/nsaids/","label":"NHS — NSAIDs: who can take them, and mixing with other medicines","quote":"Most adults can take non-steroidal anti-inflammatory drugs (NSAIDs). They're not usually recommended if you're pregnant or breastfeeding … It can cause problems if you take NSAIDs with medicines such as: other NSAIDs; anticoagulants (such as warfarin); steroids; antidepressants","accessed":"2026-08-27"},{"id":"fda_mel_meals","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, sections 2.1–2.2 (starting dose, meals), via openFDA drug/label.json","quote":"the recommended starting and maintenance oral dose of meloxicam tablets is 7.5 mg once daily … Meloxicam tablets may be taken without regard to timing of meals.","accessed":"2026-08-27"},{"id":"fda_mel_boxed2","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, boxed warning (who is at greater GI risk), via openFDA drug/label.json","quote":"Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events","accessed":"2026-08-27"},{"id":"fda_mel_di2","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 7 Drug Interactions (serotonergic drugs), via openFDA drug/label.json","quote":"concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than an NSAID alone","accessed":"2026-08-27"},{"id":"fda_mel_di3","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 7 Drug Interactions (lithium, methotrexate), via openFDA drug/label.json","quote":"NSAIDs have produced elevations in plasma lithium levels and reductions in renal lithium clearance … Concomitant use of NSAIDs and methotrexate may increase the risk for methotrexate toxicity","accessed":"2026-08-27"},{"id":"fda_mel_di4","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22meloxicam%22&limit=3","label":"US FDA label — meloxicam tablets USP, section 7 Drug Interactions (antihypertensives, diuretics), via openFDA drug/label.json","quote":"NSAIDs may diminish the antihypertensive effect of angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers … NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:24.715168+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}