Magnesium malate
Supplement
mineral chelate
energyfitness
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
A magnesium source — one of several salt forms
Pros & cons
Pros
- An authorised magnesium source in eu supplement law
- Eu panel: availability similar to other mg sources
- Counts toward the 310–420 mg/day magnesium RDA
Cons
- Limited toxicological data submitted on the malate
- Over 350 mg/day supplemental can cause diarrhoea
- No evidence it beats cheaper magnesium salts
Sources
- NIH ODS — Magnesium (Health Professional), Table 1 Recommended Dietary Allowances · read 2026-08-27
what it says
“19–30 years | 400 mg | 310 mg … 31–50 years | 420 mg | 320 mg … 51+ years | 420 mg | 320 mg”
- NIH ODS — Magnesium (Health Professional), Sources of Magnesium: Food (Daily Value) · read 2026-08-27
what it says
“The DV for magnesium is 420 mg for adults and children age 4 years and older”
- NIH ODS — Magnesium (Health Professional), Health Risks from Excessive Magnesium · read 2026-08-27
what it says
“high doses of magnesium from dietary supplements or medications can cause diarrhea, nausea, and abdominal cramping … The Tolerable Upper Intake Level for supplemental magnesium is 350 mg for adults”
- NIH ODS — Magnesium (Health Professional), Dietary Supplements (absorption by form) · read 2026-08-27
what it says
“the aspartate, citrate, lactate, and chloride forms of magnesium tend to have higher bioavailability than magnesium oxide and magnesium sulfate”
- NIH ODS — Magnesium (Health Professional), Health Risks from Excessive Magnesium (renal function) · read 2026-08-27
what it says
“The risk of magnesium toxicity increases with impaired renal function or kidney failure because the ability to remove excess magnesium is reduced or lost”
- NIH ODS — Magnesium (Health Professional), Dietary Supplements (elemental magnesium on labels) · read 2026-08-27
what it says
“The Supplement Facts panel on a dietary supplement label declares the amount of elemental magnesium in the product, not the weight of the entire magnesium-containing compound”
- NIH ODS — Magnesium (Health Professional), Interactions with Medications (bisphosphonates) · read 2026-08-27
what it says
“Magnesium-rich supplements or medications can decrease the absorption of oral bisphosphonates, such as alendronate (Fosamax) … Taking magnesium-rich supplements or medications at least 2 hours before or after oral bisphosphonates can minimize this interaction”
- NIH ODS — Magnesium (Health Professional), Interactions with Medications (antibiotics) · read 2026-08-27
what it says
“Magnesium can form insoluble complexes with tetracyclines … and with quinolone antibiotics, such as ciprofloxacin (Cipro) and levofloxacin (Levaquin). These antibiotics should be taken at least 2 hours before or 4 to 6 hours after a magnesium-containing supplement”
- NIH ODS — Magnesium (Health Professional), Interactions with Medications (diuretics) · read 2026-08-27
what it says
“Chronic treatment with loop diuretics, such as furosemide (Lasix) and bumetanide (Bumex), and thiazide diuretics … can increase the loss of magnesium in urine and lead to magnesium depletion”
- NIH ODS — Magnesium (Health Professional), Interactions with Medications (proton pump inhibitors) · read 2026-08-27
what it says
“Prescription proton pump inhibitor (PPI) drugs, such as esomeprazole magnesium (Nexium) and lansoprazole (Prevacid), can cause hypomagnesemia”
- HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. 020 (January 2026), clause 4.8 and Table 5 Minerals Limits · read 2026-08-27
what it says
“HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5. … Magnesium 350 mg”
- HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in HS and TM (Oct 2025), Annex B row 65 (Magnesium) · read 2026-08-27
what it says
“65. Magnesium … Restricted use in HS and TM … Maximum Daily Dose. When for oral use by general adult population, the maximum recommended daily dose should not provide more than 350mg”
- EFSA ANS Panel — Evaluation of di-magnesium malate (EFSA Journal 2018;16(6):e05292), Abstract · read 2026-08-27
what it says
“there was insufficient scientific evidence of a difference between the proposed novel food ingredient named as DMM and magnesium malate already authorised as a source of magnesium included in Annex II to Directive 2002/46/EC”
- EFSA ANS Panel — di-magnesium malate (EFSA Journal 2018), Abstract (bioavailability) · read 2026-08-27
what it says
“if DMM dissociates, magnesium would be available following ingestion of DMM and the availability would appear similar to values reported for other sources of magnesium already permitted”
- EFSA ANS Panel — di-magnesium malate (EFSA Journal 2018), s3.4 Biological and toxicological data · read 2026-08-27
what it says
“besides a bioavailability study conducted in human volunteers and an acute toxicity study performed in rats, no further biological and toxicological data on DMM were submitted by the applicant”
- iHerb Singapore — 'Magnesium' category page, default order, 816 results · read 2026-08-27
what it says
“Magnesium … 1 - 48 of 816 results … California Gold Nutrition … NOW Foods … Doctor's Best … Life Extension … Thorne”
Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.