{"ok":true,"entry":{"slug":"magnesium-malate","kind":"supplement","name":"magnesium malate","aliases":["Mg malate"],"brands_sg":["California Gold Nutrition","NOW Foods","Doctor's Best","Life Extension","Thorne"],"class":"mineral chelate","tags":["energy","fitness"],"use_for":"a magnesium source — one of several salt forms","use_after":null,"use_duration":null,"take_with":null,"pros":["an authorised magnesium source in eu supplement law","eu panel: availability similar to other mg sources","counts toward the 310–420 mg/day magnesium rda"],"cons":["limited toxicological data submitted on the malate","over 350 mg/day supplemental can cause diarrhoea","no evidence it beats cheaper magnesium salts"],"dose_note":"the upper limit for supplemental magnesium is 350 mg a day, and singapore caps health supplements at the same figure; labels declare elemental magnesium, not the weight of the malate compound","dosage":{"ul":350,"unit":"mg (elemental)","fda_dv":420,"rda_ai":"400–420 mg men · 310–320 mg women (19+)","ul_status":"established","population":"general adult","hsa_max_daily":350},"ul_status":"established","sg_class":null,"cautions":["impaired kidney function — the ability to clear excess magnesium is reduced","over 350 mg/day from supplements exceeds the tolerable upper intake level"],"clashes":[{"src":["nih_ods_mg_bisphos"],"note":"magnesium can lower their absorption; ods notes a 2-hour gap","with":"oral bisphosphonates (e.g. alendronate)"},{"src":["nih_ods_mg_abx"],"note":"insoluble complexes form; ods notes a 2–6 hour gap","with":"tetracycline and quinolone antibiotics"},{"src":["nih_ods_mg_diuretics"],"note":"chronic use raises urinary magnesium loss","with":"loop and thiazide diuretics"},{"src":["nih_ods_mg_ppi"],"note":"prescription ppis can cause hypomagnesemia","with":"proton pump inhibitors"}],"sources":[{"id":"nih_ods_mg_rda","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Table 1 Recommended Dietary Allowances","quote":"19–30 years | 400 mg | 310 mg … 31–50 years | 420 mg | 320 mg … 51+ years | 420 mg | 320 mg","accessed":"2026-08-27"},{"id":"nih_ods_mg_dv","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Sources of Magnesium: Food (Daily Value)","quote":"The DV for magnesium is 420 mg for adults and children age 4 years and older","accessed":"2026-08-27"},{"id":"nih_ods_mg_ul","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Health Risks from Excessive Magnesium","quote":"high doses of magnesium from dietary supplements or medications can cause diarrhea, nausea, and abdominal cramping … The Tolerable Upper Intake Level for supplemental magnesium is 350 mg for adults","accessed":"2026-08-27"},{"id":"nih_ods_mg_forms","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Dietary Supplements (absorption by form)","quote":"the aspartate, citrate, lactate, and chloride forms of magnesium tend to have higher bioavailability than magnesium oxide and magnesium sulfate","accessed":"2026-08-27"},{"id":"nih_ods_mg_renal","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Health Risks from Excessive Magnesium (renal function)","quote":"The risk of magnesium toxicity increases with impaired renal function or kidney failure because the ability to remove excess magnesium is reduced or lost","accessed":"2026-08-27"},{"id":"nih_ods_mg_label","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Dietary Supplements (elemental magnesium on labels)","quote":"The Supplement Facts panel on a dietary supplement label declares the amount of elemental magnesium in the product, not the weight of the entire magnesium-containing compound","accessed":"2026-08-27"},{"id":"nih_ods_mg_bisphos","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Interactions with Medications (bisphosphonates)","quote":"Magnesium-rich supplements or medications can decrease the absorption of oral bisphosphonates, such as alendronate (Fosamax) … Taking magnesium-rich supplements or medications at least 2 hours before or after oral bisphosphonates can minimize this interaction","accessed":"2026-08-27"},{"id":"nih_ods_mg_abx","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Interactions with Medications (antibiotics)","quote":"Magnesium can form insoluble complexes with tetracyclines … and with quinolone antibiotics, such as ciprofloxacin (Cipro) and levofloxacin (Levaquin). These antibiotics should be taken at least 2 hours before or 4 to 6 hours after a magnesium-containing supplement","accessed":"2026-08-27"},{"id":"nih_ods_mg_diuretics","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Interactions with Medications (diuretics)","quote":"Chronic treatment with loop diuretics, such as furosemide (Lasix) and bumetanide (Bumex), and thiazide diuretics … can increase the loss of magnesium in urine and lead to magnesium depletion","accessed":"2026-08-27"},{"id":"nih_ods_mg_ppi","url":"https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/","label":"NIH ODS — Magnesium (Health Professional), Interactions with Medications (proton pump inhibitors)","quote":"Prescription proton pump inhibitor (PPI) drugs, such as esomeprazole magnesium (Nexium) and lansoprazole (Prevacid), can cause hypomagnesemia","accessed":"2026-08-27"},{"id":"hsa_hs_limits","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. 020 (January 2026), clause 4.8 and Table 5 Minerals Limits","quote":"HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5. … Magnesium 350 mg","accessed":"2026-08-27"},{"id":"hsa_prohibited_mg","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in HS and TM (Oct 2025), Annex B row 65 (Magnesium)","quote":"65. Magnesium … Restricted use in HS and TM … Maximum Daily Dose. When for oral use by general adult population, the maximum recommended daily dose should not provide more than 350mg","accessed":"2026-08-27"},{"id":"efsa_dmm_auth","url":"https://europepmc.org/article/PMC/PMC7009340","label":"EFSA ANS Panel — Evaluation of di-magnesium malate (EFSA Journal 2018;16(6):e05292), Abstract","quote":"there was insufficient scientific evidence of a difference between the proposed novel food ingredient named as DMM and magnesium malate already authorised as a source of magnesium included in Annex II to Directive 2002/46/EC","accessed":"2026-08-27"},{"id":"efsa_dmm_avail","url":"https://europepmc.org/article/PMC/PMC7009340","label":"EFSA ANS Panel — di-magnesium malate (EFSA Journal 2018), Abstract (bioavailability)","quote":"if DMM dissociates, magnesium would be available following ingestion of DMM and the availability would appear similar to values reported for other sources of magnesium already permitted","accessed":"2026-08-27"},{"id":"efsa_dmm_data","url":"https://europepmc.org/article/PMC/PMC7009340","label":"EFSA ANS Panel — di-magnesium malate (EFSA Journal 2018), s3.4 Biological and toxicological data","quote":"besides a bioavailability study conducted in human volunteers and an acute toxicity study performed in rats, no further biological and toxicological data on DMM were submitted by the applicant","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/magnesium","label":"iHerb Singapore — 'Magnesium' category page, default order, 816 results","quote":"Magnesium … 1 - 48 of 816 results … California Gold Nutrition … NOW Foods … Doctor's Best … Life Extension … Thorne","accessed":"2026-08-27"}],"brand_certs":[{"brand":"Thorne","example":null,"programme":"NSF Certified for Sport","matching_products":0,"brand_total_certified":66}],"updated_at":"2026-08-30T17:59:36.026222+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}