Magnesium L-threonate

“Table 1: Recommended Dietary Allowances (RDAs) for Magnesium in Milligrams (mg) … 19–30 years | 400 mg | 310 mg … 31–50 years | 420 mg | 320 mg … 51+ years | 420 mg | 320 mg”

“The Tolerable Upper Intake Level for supplemental magnesium is 350 mg for adults … The ULs only include magnesium from dietary supplements and medications; they do not include magnesium found naturally in food and beverages”

“Small studies have found that magnesium in the aspartate, citrate, lactate, and chloride forms is absorbed more completely and is more bioavailable than magnesium oxide and magnesium sulfate”

“The risk of magnesium toxicity increases with impaired renal function or kidney failure because the ability to remove excess magnesium is reduced or lost”

“Taking magnesium-rich supplements or medications at least 2 hours before or after oral bisphosphonates can minimize this interaction … These antibiotics should be taken at least 2 hours before or 4 to 6 hours after a magnesium-containing supplement”

“Prescription proton pump inhibitor (PPI) drugs … can cause hypomagnesemia when taken for prolonged periods (typically more than a year)”

“Chronic treatment with loop diuretics … and thiazide diuretics … can increase the loss of magnesium in urine and lead to magnesium depletion … potassium-sparing diuretics … reduce magnesium excretion”

“The Supplement Facts panel on a dietary supplement label declares the amount of elemental magnesium in the product, not the weight of the entire magnesium-containing compound”

“The DV for magnesium is 420 mg for adults and children age 4 years and older”

“Compared to the placebo, Magtein® was associated with greater improvements in overall cognitive performance as measured by the NIH Total Cognition Composite (p = 0.043), with larger treatment effects on working and episodic memory”

“One hundred adults aged 18 to 45 with self-reported dissatisfied sleep were supplemented with 2 g daily of Magtein® or a placebo … two-arm, 6-week, parallel-group, randomised, double-blind, placebo-controlled trial”

“there was a greater improvement in sleep-related impairment (p = 0.043), but no group differences in changes in sleep disturbances … Based on data from the sleep tracking ring, there were no group differences in sleep outcomes”

“Magtein® was well-tolerated, and there were no reports of significant adverse reactions”

“Subjects were treated with MMFS-01 (n = 23) or placebo (n = 21) for 12 weeks … overall cognitive ability improved significantly relative to placebo (p = 0.003; Cohen's d = 0.91) … age 50-70”

“Due to the strong placebo effects on sleep and anxiety, the effects of MMFS-01 on sleep and anxiety could not be determined”

“HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5 … Table 5: Minerals Limits … Magnesium 350 mg”

“The objective of this guideline is to highlight the substances of concern … 65. Magnesium — Restricted use in HS and TM … the maximum recommended daily dose should not provide more than 350mg”

“California Gold Nutrition, Magnesium Bisglycinate Chelate, Albion TRAACS® … NOW Foods, Magnesium Glycinate … Doctor's Best, High Absorption Magnesium Lysinate Glycinate … Life Extension, Neuro-Mag®, Magnesium L-Threonate … Thorne, Magnesium Glycinate”