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Lisdexamfetamine

Medication CNS stimulant prodrug mental health
Aka: Vyvanse
Brands seen in Singapore: Vyvanse
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
SG label: adhd, in patients aged 6 and above
When to take
SG label: in the morning; afternoon doses are avoided
Take with
HealthHub: with or without food · capsule swallowed whole
Pros & cons
Pros
  • SG label: one morning dose covers the day
  • 20, 30, 40, 50, 60 and 70 mg capsules registered in SG
  • SG label: capsule may be opened and mixed into water
Cons
  • HealthHub: it may become habit-forming or be abused
  • SG label: not indicated or recommended for weight loss
  • HealthHub: appetite loss and poor sleep are common
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 27 Aug 2026 · read 2026-08-27
    what it says
    “VYVANSE CAPSULES 20/30/40/50/60/70 mg SIN15840P, SIN15841P, SIN15842P, SIN15843P, SIN15844P, SIN15845P | Lisdexamfetamine Dimesylate | Prescription Only | N06BA12 | CAPSULE — the only 6 lisdexamfetamine rows in the register”
  2. MOH National Drug Formulary (Singapore) — VYVANSE CAPSULES 20 MG [SIN15840P], product information · read 2026-08-27
    what it says
    “LISDEXAMFETAMINE DIMESYLATE - 20 MG … Registration Number SIN15840P … Licence Holder TAKEDA PHARMACEUTICALS (ASIA PACIFIC) PTE. LTD. … Forensic Classification PRESCRIPTION ONLY MEDICINES … ATC code N06BA12 … Exemptions for Supply without Prescription NA”
  3. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 1 Indications and Usage · read 2026-08-27
    what it says
    “VYVANSE is indicated for the treatment of: Attention Deficit Hyperactivity Disorder (ADHD) … Limitation of Use: VYVANSE is not indicated or recommended for weight loss”
  4. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 2.2 General Instructions for Use · read 2026-08-27
    what it says
    “Take VYVANSE by mouth in the morning with or without food; avoid afternoon doses because of the potential for insomnia … Swallow VYVANSE capsules whole, or open capsules, empty and mix the entire contents with yogurt, water, or orange juice”
  5. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 2.3 Dosage for Treatment of ADHD · read 2026-08-27
    what it says
    “The recommended starting dose is 30 mg once daily in the morning in patients aged 6 and above … Dosage may be adjusted … up to maximum dose of 70 mg/day”
  6. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 2.4 Dosage in Patients with Renal Impairment · read 2026-08-27
    what it says
    “In patients with severe renal impairment (GFR 15 to < 30 mL/min/1.73 m2), the maximum dose should not exceed 50 mg/day. In end stage renal disease … the maximum recommended dose is 30 mg/day”
  7. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 2.1 Pre-treatment Screening · read 2026-08-27
    what it says
    “Prior to treating children, adolescents, and adults with CNS stimulants, including VYVANSE, assess for the presence of cardiac disease … To reduce the abuse of CNS stimulants including VYVANSE, assess the risk of abuse, prior to prescribing”
  8. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 2.5 Dosage Modifications due to Drug Interactions · read 2026-08-27
    what it says
    “Agents that alter urinary pH can impact urinary excretion and alter blood levels of amphetamine. Acidifying agents (e.g., ascorbic acid) decrease blood levels, while alkalinizing agents (e.g., sodium bicarbonate) increase blood levels”
  9. MOH National Drug Formulary (Singapore) — VYVANSE [SIN15840P], 4 Contraindications · read 2026-08-27
    what it says
    “Known hypersensitivity to amphetamine products … Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis … Pheochromocytoma”
  10. HealthHub (MOH Singapore) — Lisdexamfetamine, medication information leaflet · read 2026-08-27
    what it says
    “Lisdexamfetamine can be used to treat the symptoms of Attention-Deficit Hyperactivity Disorder (ADHD), alongside educational, social and psychological methods … Lisdexamfetamine may be taken with or without food. The capsule should be swallowed whole”
  11. HealthHub (MOH Singapore) — Lisdexamfetamine, precautions · read 2026-08-27
    what it says
    “You are taking, or have stopped taking in the last 14 days, a class of medication called Monoamine oxidase inhibitors (MAOIs) … Some of them may … cause serious drug interactions”
  12. HealthHub (MOH Singapore) — Lisdexamfetamine, IMPORTANT box · read 2026-08-27
    what it says
    “Lisdexamfetamine may become habit-forming or abused by some people … As Lisdexamfetamine is a controlled substance, it should be kept safely and handled responsibly, do not sell or give it to other people”
  13. HealthHub (MOH Singapore) — Lisdexamfetamine, common side effects · read 2026-08-27
    what it says
    “Nausea or vomiting or stomach discomfort … Loss of appetite … Weight loss may occur during the treatment … Difficulty sleeping … Dizziness … Dry mouth … Headache or irritability … Mild nervousness”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.