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Lactobacillus rhamnosus

Supplement probiotic gutimmune
Aka: LGG, L. rhamnosus GG, Lacticaseibacillus rhamnosus
Brands seen in Singapore: California Gold Nutrition, 21st Century, Garden of Life, NOW Foods, Lemme
Third-party tested: Garden of Life, Lemme certify other products with NSF Certified for Sport, but nothing for lactobacillus rhamnosus.Certification is granted per product, so check the tub you actually own. Not being listed is not the same as failing.
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Antibiotic-associated diarrhoea, mainly in children
When to take
Aad trials ran during the antibiotic course
Take with
Milk — a fermented milk drink was the trial vehicle
Pros & cons
Pros
  • Aad risk fell from 22.4% to 12.3% across 11 RCTS
  • Fewer upper respiratory infections in day-care kids
  • IBS pain in children improved (3 RCTS, n=167)
Cons
  • In adults alone the aad difference was not significant
  • Quality of evidence rated moderate to low
  • No gut-infection benefit in the day-care trial
Sources
  1. NIH NCCIH — Probiotics: Usefulness and Safety · read 2026-08-27
    what it says
    “Different types of probiotics may have different effects. For example, if a specific kind of Lactobacillus helps prevent an illness, that doesn't necessarily mean that another kind of Lactobacillus … would do the same thing.”
  2. NIH NCCIH — Probiotics: Usefulness and Safety, "Can probiotics be harmful?" · read 2026-08-27
    what it says
    “The risk of harmful effects from probiotics is greater in people with severe illnesses or compromised immune systems … Cases of severe or fatal infections have been reported in premature infants who were given probiotics”
  3. Systematic review with meta-analysis: Lactobacillus rhamnosus GG in the prevention of antibiotic-associated diarrhoea in children and adults (Szajewska & Kołodziej, Aliment Pharmacol Ther 2015) · read 2026-08-27
    what it says
    “reduced the risk of AAD in patients treated with antibiotics from 22.4% to 12.3% … In adults, the difference was not significant … the quality of evidence is moderate to low”
  4. Lactobacillus GG in the prevention of gastrointestinal and respiratory tract infections in children who attend day care centers (Hojsak et al., Clin Nutr 2010) · read 2026-08-27
    what it says
    “children in the LGG group had a significantly reduced risk of upper respiratory tract infections … no significant reduction in the risk of gastrointestinal infections … at a dose of 10(9) colony-forming units in 100ml of a fermented milk product”
  5. Meta-analysis: Lactobacillus rhamnosus GG for abdominal pain-related functional gastrointestinal disorders in childhood (Horvath et al., Aliment Pharmacol Ther 2011) · read 2026-08-27
    what it says
    “LGG supplementation was associated with a significantly higher rate of treatment responders … in the irritable bowel syndrome (IBS) subgroup (three RCTs, n = 167; RR 1.70, 95% CI 1.27-2.27, NNT 4)”
  6. iHerb Singapore — Probiotics category page (default best-selling order) · read 2026-08-27
    what it says
    “California Gold Nutrition, LactoBif® 30 Probiotics, 60 Veggie Capsules”
  7. HSA — Guidelines on prohibited and restricted ingredients in HS and TM (Oct 2025), Annex A/B · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  8. HSA — Health Supplements Guidelines (Jan 2026), working definition and Tables 4–5 · read 2026-08-27
    what it says
    “Vitamins, minerals, amino acids, fatty acids, enzymes, probiotics and other bioactive substances … Table 4: Vitamins Limits … Table 5: Minerals Limits”
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Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.