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Lactobacillus reuteri

Supplement probiotic gutimmune
Aka: L. reuteri, Limosilactobacillus reuteri
Brands seen in Singapore: California Gold Nutrition, 21st Century, Garden of Life, NOW Foods, Lemme
Third-party tested: Garden of Life, Lemme certify other products with NSF Certified for Sport, but nothing for lactobacillus reuteri.Certification is granted per product, so check the tub you actually own. Not being listed is not the same as failing.
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Infant colic in breastfed babies; childhood diarrhoea
Take with
Given orally to infants in the colic trials
Studied for
Colic trials read out at day 21
Pros & cons
Pros
  • Less crying and fussing time than placebo
  • Diarrhoea duration fell ~25 h in treatment trials
  • No safety concerns in non-immunocompromised people
Cons
  • Colic effect insignificant in formula-fed babies
  • No drop in hospital-acquired diarrhoea risk
  • Trial doses varied 4-fold between studies
Sources
  1. NIH NCCIH — Probiotics: Usefulness and Safety · read 2026-08-27
    what it says
    “A 2018 review of 7 studies (471 participants) of probiotics for colic, 5 of which involved the probiotic Lactobacillus reuteri DSM 17938, found that this probiotic was associated with successful treatment”
  2. NIH NCCIH — Probiotics: Usefulness and Safety, "Can probiotics be harmful?" · read 2026-08-27
    what it says
    “The risk of harmful effects from probiotics is greater in people with severe illnesses or compromised immune systems … Cases of severe or fatal infections have been reported in premature infants who were given probiotics”
  3. Lactobacillus reuteri to treat infant colic: a meta-analysis (Sung et al., Pediatrics 2018) · read 2026-08-27
    what it says
    “double-blind randomized controlled trials … of L reuteri DSM17398 versus a placebo, delivered orally to infants with colic … The probiotic group averaged less crying and/or fussing time … Intervention effects … were insignificant in formula-fed infants”
  4. Systematic review with meta-analysis: Lactobacillus reuteri DSM 17938 for diarrhoeal diseases in children (Szajewska et al., Aliment Pharmacol Ther 2016) · read 2026-08-27
    what it says
    “In treatment trials, L. reuteri administration reduced the duration of diarrhoea (three RCTs, n = 256, mean difference, MD -24.82 h) … there was no significant reduction in the risk of nosocomial diarrhoea”
  5. The efficacy of Lactobacillus reuteri DSM 17938 in infants and children: a review of the current evidence (Urbańska & Szajewska, Eur J Pediatr 2014) · read 2026-08-27
    what it says
    “The daily dose of L. reuteri DSM 17938 ranged from 1 × 10 8 to 4 × 10 8 colony-forming units (CFU) … There are no safety concerns with regard to the use of L. reuteri in nonimmunocompromised subjects”
  6. iHerb Singapore — Probiotics category page (default best-selling order) · read 2026-08-27
    what it says
    “California Gold Nutrition, LactoBif® 30 Probiotics, 60 Veggie Capsules”
  7. HSA — Guidelines on prohibited and restricted ingredients in HS and TM (Oct 2025), Annex A/B · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  8. HSA — Health Supplements Guidelines (Jan 2026), working definition and Tables 4–5 · read 2026-08-27
    what it says
    “Vitamins, minerals, amino acids, fatty acids, enzymes, probiotics and other bioactive substances … Table 4: Vitamins Limits … Table 5: Minerals Limits”
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Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.