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Ketoconazole

Medication azole antifungal skin
Aka: Nizoral
Brands seen in Singapore: Nitozol, Ninazol, Phytoral, Pristinex, Pristine
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
SG label (shampoo): dandruff, seborrhoeic dermatitis
When to take
SG label: left on 3 to 5 minutes, then rinsed off
Take with
NHS: 30 minutes before other creams on the SAMe skin
Pros & cons
Pros
  • SG label: a palmful or one sachet is enough per wash
  • SG register: SG shampoos are all general sale list
  • NHS: only tiny amounts absorbed from cream or shampoo
Cons
  • US label: oral tablets carry a boxed liver warning
  • SG label: shampoo not for children under 12 years
  • NHS: too much may leave skin irritated or red
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 27 Aug 2026 · read 2026-08-27
    what it says
    “21 ketoconazole rows split by form: all 7 SHAMPOOS General Sale List (NIZORAL SIN04926P, NINAZOL, NITOZOL, PRISTINE, SEBIZOLE, YUCOMY, DEZOR); CREAMS split — NIZORAL SIN01117P and YUCOMY GSL, NITOZOL/PRISTINEX/ANTANAZOL/DEZOR/FORMYCO and PHYTORAL OINTMENT Pharmacy Only; all 6 oral TABLETS Prescription Only”
  2. MOH National Drug Formulary (Singapore) — NIZORAL SHAMPOO 20 MG/G [SIN04926P], product information · read 2026-08-27
    what it says
    “KETOCONAZOLE - 20 MG/G … Dosage Form SHAMPOO … Registration Number SIN04926P … Licence Holder APEX PHARMA MARKETING PTE. LTD. … Forensic Classification GENERAL SALE LIST … ATC code D01AC08”
  3. MOH National Drug Formulary (Singapore) — NIZORAL SHAMPOO [SIN04926P], what it is for · read 2026-08-27
    what it says
    “a medicine to treat and prevent the relapse of skin infections caused by fungi or yeasts … scales on the scalp (dandruff) … (seborrheic dermatitis) … not recommended for use in infants and children below the age of 12 years”
  4. MOH National Drug Formulary (Singapore) — NIZORAL SHAMPOO [SIN04926P], how to use and how much · read 2026-08-27
    what it says
    “allow the product to soak in for 3 to 5 minutes before rinsing … a palmful or 1 sachet of shampoo suffices for one wash … For treatment, twice a week for 2 to 4 weeks”
  5. MOH National Drug Formulary (Singapore) — NIZORAL SHAMPOO [SIN04926P], when not to use it · read 2026-08-27
    what it says
    “Do not use Nizoral Shampoo if you know you are hypersensitive (allergic) to it. Symptoms of hypersensitivity include itching and red skin, occurring after application”
  6. NHS medicines A–Z — Ketoconazole: an antifungal medicine used to treat skin infections (reviewed 16 August 2024) · read 2026-08-27
    what it says
    “Ketoconazole - Brand names: Daktarin Gold, Daktarin Intensiv, Dandrazol, Nizoral … Find out how ketoconazole cream and shampoo treats fungal skin infections and how to use it”
  7. NHS medicines A–Z — How and when to use ketoconazole · read 2026-08-27
    what it says
    “Use the cream once or twice a day on the infected skin … Use the shampoo twice a week for 2 to 4 weeks … If you use too much … it may make your skin irritated or red”
  8. NHS medicines A–Z — How and when to use ketoconazole, using other products on the same skin · read 2026-08-27
    what it says
    “After putting on the ketoconazole cream, wait 30 minutes before you use different products on the same area. This gives the ketoconazole time to be absorbed into your skin”
  9. NHS medicines A–Z — Using ketoconazole with other medicines and herbal supplements · read 2026-08-27
    what it says
    “Only tiny amounts of ketoconazole are absorbed into your body when you use it as a cream or shampoo … put the steroid cream on in the morning and the put the ketoconazole cream on in the evening”
  10. Ketoconazole tablets (oral) — US prescribing information, openFDA drug label record, Boxed Warning · read 2026-08-27
    what it says
    “Serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation has occurred with the use of oral ketoconazole … Co-administration of the following drugs with ketoconazole is contraindicated: dofetilide, quinidine, pimozide, lurasidone, cisapride, methadone, disopyramide, dronedarone, ranolazine”
  11. Ketoconazole tablets (oral) — US prescribing information, Dosage and Administration · read 2026-08-27
    what it says
    “The recommended starting dose of ketoconazole tablets is a single daily administration of 200 mg (one tablet). If clinical responsiveness is insufficient within the expected time, the dose … may be increased to 400 mg (two tablets) once daily”
  12. Ketoconazole tablets (oral) — US prescribing information, Contraindications · read 2026-08-27
    what it says
    “the following other drugs are contraindicated with ketoconazole tablets: methadone, disopyramide, dronedarone, ergot alkaloids … irinotecan, lurasidone, oral midazolam, alprazolam, triazolam, felodipine, nisoldipine, ranolazine, tolvaptan, eplerenone, lovastatin, simvastatin and colchicine”
  13. Ketoconazole tablets (oral) — US prescribing information, Indications and Usage · read 2026-08-27
    what it says
    “Ketoconazole tablets are not indicated for treatment of onychomycosis, cutaneous dermatophyte infections, or Candida infections … should be used only when other effective antifungal therapy is not available or tolerated”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.