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Itraconazole

Medication azole antifungal other
Aka: Sporanox
Brands seen in Singapore: Sporanox, Canditral, Unitrac
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Fungal infections of skin, nails, mouth and organs (SG)
When to take
HealthHub: immediately after a full meal, swallowed whole
Take with
A full meal · HealthHub: no alcoholic drinks while on it
Pros & cons
Pros
  • SG label: nail, skin and systemic fungal infections
  • HealthHub: taken right after a full meal for absorption
  • US label: 200 mg once daily is the usual starting dose
Cons
  • SG label: pregnancy only in life-threatening cases
  • SG label: not with heart failure, now or in the past
  • HealthHub: clashes with statins, digoxin and midazolam
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 4 registered itraconazole products read 'Prescription Only' — SIN08206P SPORANOX CAPSULE 100 mg · SIN11355P CANDITRAL CAPSULE 100 mg · SIN12459P UNITRAC CAPSULE 100 mg · SIN16379P JAMP ITRACONAZOLE ORAL SOLUTION 10MG/ML”
  2. HealthHub (MOH Singapore) — Itraconazole: what it is for and how to take it (reviewed 21 Jan 2026) · read 2026-08-27
    what it says
    “Itraconazole is used to treat fungal infections … Itraconazole should be taken immediately after a full meal. Capsules should be swallowed whole. Complete the course as prescribed by the doctor.”
  3. HealthHub (MOH Singapore) — Itraconazole: precautions and drug interactions · read 2026-08-27
    what it says
    “The amount or levels of digoxin, midazolam and cyclosporine in the blood may be increased … risk of muscle weakness if combined with cholesterol lowering drugs such as simvastatin or atorvastatin … phenytoin and rifampicin can decrease the blood level”
  4. HealthHub (MOH Singapore) — Itraconazole: precautions on pregnancy and contraception · read 2026-08-27
    what it says
    “Effective contraception is recommended for any woman who is taking itraconazole, and who could potentially become pregnant during treatment and for 2 months following the end of treatment.”
  5. HealthHub (MOH Singapore) — Itraconazole: common side effects, food and drink · read 2026-08-27
    what it says
    “Some side effects of these medications include: Nausea, vomiting, stomach upset … Diarrhoea … Headache … Avoid alcoholic drinks while you are taking this medication.”
  6. National Drug Formulary (SG, MOH) — SPORANOX CAPSULE 100 MG [SIN08206P]: approved indications · read 2026-08-27
    what it says
    “Treatment of dermatomycosis, including highly keratinized regions as in plantar tinea pedis and palmar tinea manus; Treatment of pityriasis versicolor; Treatment of oral candidosis … Treatment of onychomycosis … systemic aspergillosis and candidosis”
  7. National Drug Formulary (SG, MOH) — SPORANOX CAPSULE 100 MG [SIN08206P]: dosage and administration · read 2026-08-27
    what it says
    “For optimal absorption, administer SPORANOX capsules immediately after a full meal. The capsules must be swallowed whole … Optimal clinical and mycological response is thus reached 2 to 4 weeks after the cessation of treatment for skin infections”
  8. National Drug Formulary (SG, MOH) — SPORANOX CAPSULE 100 MG [SIN08206P]: contraindications · read 2026-08-27
    what it says
    “SPORANOX capsules must not be used during pregnancy (except for life-threatening cases) … should not be administered to patients with evidence of ventricular dysfunction such as congestive heart failure (CHF) or a history of CHF”
  9. US FDA label — SPORANOX (itraconazole) Capsules, DOSAGE AND ADMINISTRATION, via openFDA · read 2026-08-27
    what it says
    “The recommended dose is 200 mg once daily (2 capsules) … the dose should be increased in 100-mg increments to a maximum of 400 mg daily. Doses above 200 mg/day should be given in two divided doses.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.