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Insulin glargine

Medication long-acting insulin diabetes
Aka: Lantus, Toujeo, Basaglar
Brands seen in Singapore: Lantus, Toujeo, Semglee
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed to lower high blood sugar in diabetes
When to take
HealthHub: usually once a day, SAMe time every day
Take with
Injected under the skin · with or without food
Pros & cons
Pros
  • HealthHub: once a day, with or without food
  • FDA: given at any time of day, SAMe time daily
  • HealthHub: abdomen gives the most consistent uptake
Cons
  • HealthHub: low blood sugar is the main side effect
  • FDA: hypokalaemia may be life-threatening
  • HealthHub: lumps or dents if sites are not rotated
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 6 registered insulin glargine products read Forensicclassification 'Prescription Only' — SIN11934P LANTUS 100 Units/ml vial · SIN13426P Lantus SoloStar · SIN15138P Toujeo SoloStar 300 units/ml · SIN16009P SEMGLEE 100U/ml; the two SOLIQUA rows are lixisenatide combinations.”
  2. HealthHub (Pharmaceutical Society of Singapore) — Insulin Glargine: what is this medication for · read 2026-08-27
    what it says
    “Glargine is a long-acting insulin. It is used to reduce high blood sugar levels in patients with diabetes mellitus.”
  3. HealthHub — Insulin Glargine: how should I use this medication · read 2026-08-27
    what it says
    “Insulin Glargine is usually given once a day with or without food as an injection into the fatty tissue that is between the skin and muscle layer.”
  4. HealthHub — Insulin Glargine: what precautions should I take · read 2026-08-27
    what it says
    “Inform your healthcare professional if you: … Drink alcohol often; Are eating less than usual due to sickness/a changed diet as your dosage may need to be changed; Are travelling across different time zones …; Are pregnant or breastfeeding”
  5. HealthHub — Insulin Glargine: common side effects · read 2026-08-27
    what it says
    “This medication may cause low blood sugar (hypoglycemia). Symptoms of low blood sugar include: Weakness; Dizziness; Hunger; Sweating; Trembling; Blurred vision … Some patients may also experience … a small lump or dent of the skin at the injection site.”
  6. HealthHub — Insulin Glargine: what food or medication should I avoid · read 2026-08-27
    what it says
    “Avoid taking alcohol with this medication as this may increase your risk of having low blood sugar.”
  7. US FDA label — BASAGLAR KwikPen (insulin glargine), section 2 Dosage and Administration, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Individualize dosage based on metabolic needs, blood glucose monitoring, glycemic control, type of diabetes, prior insulin use … Administer subcutaneously once daily at any time of day, but at the same time every day.”
  8. US FDA label — BASAGLAR KwikPen (insulin glargine), section 5 Warnings and Precautions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Never share a BASAGLAR prefilled pen between patients, even if the needle is changed … Hypoglycemia: May be life-threatening … Hypersensitivity reactions: Severe, life-threatening, generalized allergy, including anaphylaxis, can occur … Hypokalemia: May be life-threatening.”
  9. US FDA label — BASAGLAR KwikPen (insulin glargine), section 7 Drug Interactions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Drugs That May Increase the Risk of Hypoglycemia … Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors … Drugs That May Decrease the Blood Glucose Lowering Effect … corticosteroids, danazol, diuretics, estrogens”
  10. HealthHub — Insulin Glargine: how to select an injection site · read 2026-08-27
    what it says
    “Your abdomen or stomach area is the best site for injection as it provides the fastest and most consistent absorption of insulin.”
  11. US FDA label — BASAGLAR KwikPen (insulin glargine), section 2.2 device dose limit, via openFDA drug/label.json · read 2026-08-27
    what it says
    “The BASAGLAR prefilled pens each dials in 1 unit increments and delivers a maximum dose of 80 units per injection.”
  12. US FDA label — BASAGLAR KwikPen (insulin glargine), section 2.3 Initiation of therapy, via openFDA drug/label.json · read 2026-08-27
    what it says
    “The recommended starting dose of BASAGLAR in patients with type 2 diabetes is 0.2 units/kg or up to 10 units once daily.”
  13. US FDA label — BASAGLAR KwikPen (insulin glargine), section 2.1 Important Administration Instructions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Do not dilute or mix BASAGLAR with any other insulin or solution. Do not administer intravenously or via an insulin pump.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.