{"ok":true,"entry":{"slug":"insulin-glargine","kind":"medication","name":"insulin glargine","aliases":["Lantus","Toujeo","Basaglar"],"brands_sg":["Lantus","Toujeo","Semglee"],"class":"long-acting insulin","tags":["diabetes"],"use_for":"prescribed to lower high blood sugar in diabetes","use_after":"healthhub: usually once a day, same time every day","use_duration":null,"take_with":"injected under the skin · with or without food","pros":["healthhub: once a day, with or without food","fda: given at any time of day, same time daily","healthhub: abdomen gives the most consistent uptake"],"cons":["healthhub: low blood sugar is the main side effect","fda: hypokalaemia may be life-threatening","healthhub: lumps or dents if sites are not rotated"],"dose_note":"the us fda label for basaglar (insulin glargine) carries no maximum daily dose — it says to 'individualize dosage based on metabolic needs, blood glucose monitoring, glycemic control, type of diabetes, prior insulin use' and gives a type 2 starting dose of '0.2 units/kg or up to 10 units once daily'; the only ceiling on the page is the device one, 'the BASAGLAR prefilled pens each dials in 1 unit increments and delivers a maximum dose of 80 units per injection'. sg-registered strengths are 100 units/ml (lantus, semglee) and 300 units/ml (toujeo). in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["drinking alcohol often (healthhub)","eating less than usual, or unwell (healthhub)","travel across time zones (healthhub)","pregnancy or breastfeeding (healthhub)"],"clashes":[{"src":["hh_gla_food"],"food":true,"note":"healthhub: may increase the risk of low blood sugar","with":"alcohol"},{"src":["fda_gla_di"],"note":"fda lists these among drugs that may increase the risk of hypoglycaemia","with":"ace inhibitors, fibrates, fluoxetine, maois, salicylates"},{"src":["fda_gla_di"],"note":"fda lists these among drugs that may decrease the blood-glucose-lowering effect","with":"corticosteroids, diuretics, oral contraceptives, thyroid hormones"},{"src":["fda_gla_mix"],"note":"fda: do not dilute or mix basaglar with any other insulin or solution","with":"other insulins and solutions"},{"src":["fda_gla_di"],"note":"fda: monitor glucose more often when co-administered antidiabetic agents change","with":"other glucose-lowering medicines"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 6 registered insulin glargine products read Forensicclassification 'Prescription Only' — SIN11934P LANTUS 100 Units/ml vial · SIN13426P Lantus SoloStar · SIN15138P Toujeo SoloStar 300 units/ml · SIN16009P SEMGLEE 100U/ml; the two SOLIQUA rows are lixisenatide combinations.","accessed":"2026-08-27"},{"id":"hh_gla_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-glargine","label":"HealthHub (Pharmaceutical Society of Singapore) — Insulin Glargine: what is this medication for","quote":"Glargine is a long-acting insulin. It is used to reduce high blood sugar levels in patients with diabetes mellitus.","accessed":"2026-08-27"},{"id":"hh_gla_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-glargine","label":"HealthHub — Insulin Glargine: how should I use this medication","quote":"Insulin Glargine is usually given once a day with or without food as an injection into the fatty tissue that is between the skin and muscle layer.","accessed":"2026-08-27"},{"id":"hh_gla_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-glargine","label":"HealthHub — Insulin Glargine: what precautions should I take","quote":"Inform your healthcare professional if you: … Drink alcohol often; Are eating less than usual due to sickness/a changed diet as your dosage may need to be changed; Are travelling across different time zones …; Are pregnant or breastfeeding","accessed":"2026-08-27"},{"id":"hh_gla_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-glargine","label":"HealthHub — Insulin Glargine: common side effects","quote":"This medication may cause low blood sugar (hypoglycemia). Symptoms of low blood sugar include: Weakness; Dizziness; Hunger; Sweating; Trembling; Blurred vision … Some patients may also experience … a small lump or dent of the skin at the injection site.","accessed":"2026-08-27"},{"id":"hh_gla_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-glargine","label":"HealthHub — Insulin Glargine: what food or medication should I avoid","quote":"Avoid taking alcohol with this medication as this may increase your risk of having low blood sugar.","accessed":"2026-08-27"},{"id":"fda_gla_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22insulin+glargine%22&limit=3","label":"US FDA label — BASAGLAR KwikPen (insulin glargine), section 2 Dosage and Administration, via openFDA drug/label.json","quote":"Individualize dosage based on metabolic needs, blood glucose monitoring, glycemic control, type of diabetes, prior insulin use … Administer subcutaneously once daily at any time of day, but at the same time every day.","accessed":"2026-08-27"},{"id":"fda_gla_warn","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22insulin+glargine%22&limit=3","label":"US FDA label — BASAGLAR KwikPen (insulin glargine), section 5 Warnings and Precautions, via openFDA drug/label.json","quote":"Never share a BASAGLAR prefilled pen between patients, even if the needle is changed … Hypoglycemia: May be life-threatening … Hypersensitivity reactions: Severe, life-threatening, generalized allergy, including anaphylaxis, can occur … Hypokalemia: May be life-threatening.","accessed":"2026-08-27"},{"id":"fda_gla_di","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22insulin+glargine%22&limit=3","label":"US FDA label — BASAGLAR KwikPen (insulin glargine), section 7 Drug Interactions, via openFDA drug/label.json","quote":"Drugs That May Increase the Risk of Hypoglycemia … Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors … Drugs That May Decrease the Blood Glucose Lowering Effect … corticosteroids, danazol, diuretics, estrogens","accessed":"2026-08-27"},{"id":"hh_gla_site","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-glargine","label":"HealthHub — Insulin Glargine: how to select an injection site","quote":"Your abdomen or stomach area is the best site for injection as it provides the fastest and most consistent absorption of insulin.","accessed":"2026-08-27"},{"id":"fda_gla_pen","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22insulin+glargine%22&limit=3","label":"US FDA label — BASAGLAR KwikPen (insulin glargine), section 2.2 device dose limit, via openFDA drug/label.json","quote":"The BASAGLAR prefilled pens each dials in 1 unit increments and delivers a maximum dose of 80 units per injection.","accessed":"2026-08-27"},{"id":"fda_gla_start","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22insulin+glargine%22&limit=3","label":"US FDA label — BASAGLAR KwikPen (insulin glargine), section 2.3 Initiation of therapy, via openFDA drug/label.json","quote":"The recommended starting dose of BASAGLAR in patients with type 2 diabetes is 0.2 units/kg or up to 10 units once daily.","accessed":"2026-08-27"},{"id":"fda_gla_mix","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22insulin+glargine%22&limit=3","label":"US FDA label — BASAGLAR KwikPen (insulin glargine), section 2.1 Important Administration Instructions, via openFDA drug/label.json","quote":"Do not dilute or mix BASAGLAR with any other insulin or solution. Do not administer intravenously or via an insulin pump.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:23.779398+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}