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Hyoscine hydrobromide

Medication antimuscarinic antiemetic digestive
Aka: scopolamine, Kwells, Scopoderm
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Travel and motion sickness — nausea and vomiting
When to take
NHS: a dose 20–30 min before a journey; patch 5–6 h
Take with
Tablets sucked, chewed or swallowed, with or without food
Pros & cons
Pros
  • UK label: for the prevention of travel sickness
  • NHS: pharmacies sell 150 and 300 microgram tablets
  • NHS: one patch can stay on for up to 72 hours
Cons
  • Not on the HSA register — no SG-registered product
  • UK label: drowsiness, dry mouth, blurred vision
  • UK label: glaucoma or prostate enlargement rules it out
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), all 5,511 rows cached at /tmp/hsa_all.json and filtered locally, never re-fetched · read 2026-08-27
    what it says
    “Zero rows match "hyoscine hydrobromide" or "scopolamine". All 10 "HYOSCINE" rows are HYOSCINE BUTYLBROMIDE or HYOSCINE N-BUTYLBROMIDE, ATC A03BB01 — a different salt (BUSCOPAN, DHACOPAN, HYOMIDE, SPASMOLIV, FUCON, HYOSUN, COSPAN, COPAN).”
  2. NHS — Hyoscine hydrobromide (Kwells and Joy-Rides), medicine landing page · read 2026-08-27
    what it says
    “Hyoscine hydrobromide (Kwells and Joy-Rides) - Other brand names: Kwells Kids, Travel Calm, Scopoderm. Find out how hyoscine hydrobromide treats travel sickness and how to take it.”
  3. NHS — How and when to take hyoscine hydrobromide: tablets · read 2026-08-27
    what it says
    “Pharmacies sell 2 different strengths … 150 micrograms … 300 micrograms … a dose at least 20 to 30 minutes before starting your journey … Suck or chew the tablets, or swallow them whole … with or without food.”
  4. NHS — How and when to take hyoscine hydrobromide: patches for travel sickness · read 2026-08-27
    what it says
    “Stick a patch to the skin behind the ear, 5 to 6 hours before the start of your journey … keep the patch on for up to 72 hours … Do not apply more than 1 patch at a time.”
  5. NHS — Who can and cannot take hyoscine hydrobromide · read 2026-08-27
    what it says
    “tell a pharmacist or doctor before taking it if you … have primary angle closure glaucoma … myasthenia gravis … heart problems … thyroid, kidney or liver problems … epilepsy … are pregnant or trying to get pregnant”
  6. emc (UK SmPC) — Kwells 300 microgram tablets, sections 1–4.1, Dexcel-Pharma, revised 19/11/2025 · read 2026-08-27
    what it says
    “Kwells 300 microgram tablets … Hyoscine Hydrobromide 300 microgram … Therapeutic indications: For the prevention of travel sickness.”
  7. emc (UK SmPC) — Kwells 300 microgram tablets, section 4.2 Posology and method of administration · read 2026-08-27
    what it says
    “Tablets to be sucked, chewed or swallowed. Adults: 1 tablet every 6 hours if required. Do not take more than 3 tablets in 24 hours. Children over 10: ½-1 tablet every 6 hours if required.”
  8. emc (UK SmPC) — Kwells 300 microgram tablets, section 4.3 Contraindications · read 2026-08-27
    what it says
    “Prostatic enlargement, paralytic ileus, pyloric stenosis, glaucoma and myasthenia gravis. In addition, Kwells should not be given to patients with a known sensitivity to hyoscine hydrobromide or any other component of the product.”
  9. emc (UK SmPC) — Kwells 300 microgram tablets, section 4.4 Special warnings and precautions for use · read 2026-08-27
    what it says
    “those at risk of acute urinary retention, or with cardiovascular, metabolic, gastrointestinal, liver or renal disease, or suffering from CNS disorders such as seizures should consult a doctor … Hyperthermia can occur at high ambient temperatures due to decreased sweating”
  10. emc (UK SmPC) — Kwells 300 microgram tablets, section 4.8 Undesirable effects · read 2026-08-27
    what it says
    “blurred vision, mydriasis … dry mouth … drowsiness, dizziness, sedation and somnolence are commonly reported … There have been rare reports of an increase in seizure frequency in epileptic patients.”
  11. emc (UK SmPC) — Kwells 300 microgram tablets, section 4.5 Interaction with other medicinal products · read 2026-08-27
    what it says
    “effects of hyoscine may be enhanced by other drugs with anticholinergic properties (including amantadine, some antihistamines, phenothiazine antipsychotics and tricyclic antidepressants) … increased risk of side effects when given with MAOIs … antagonism of effect of domperidone and metoclopramide”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.